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Is telmisartan effective in treating non-alcoholic steatohepatitis?
Date:3/3/2009

pact on liver fibrosis. The potentially advantage for using ARBs in NASH/NAFLD resides in a more tailored action on the tissular targets, by interfering solely the AT1 receptors of angiotensin and thus providing a more clear-cut effect. However, not all ARBs have similar potencies in NASH/NAFLD, perhaps given to some different "second-level"pharmacologic effects such as the specific PPAR-gamma ligand effect of telmisartan and maybe some other some "concealed" mechanisms that further studies will undoubtedly unveil.


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Contact: Lai-Fu Li
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

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