Navigation Links
Is somatic hypersensitivity a predictor of irritable bowel syndrome?
Date:7/22/2009

Although visceral hypersensitivity is considered a hallmark feature of IBS, conflicting evidence exists regarding somatic hypersensitivity in this patient population. Several investigators have found no evidence for heightened somatic pain sensitivity in IBS patients. Also, others have reported similar cold presser pain tolerance in IBS patients and controls. These conflicting findings may result from differing somatic pain testing procedures. Previous studies have explored the correlates of visceral hypersensitivity among patients with IBS. To further evaluate somatic hyperalgesia among patients with IBS, the authors evaluated thermal pain sensitivity among patients with diarrhea-predominant IBS (D-IBS) vs constipation-predominant IBS (C-IBS) compared with healthy subjects.

A research led by G Nicholas Verne from United States addressed this issue. The article is to be published on July 14, 2009 in the World Journal of Gastroenterology. A total of 42 cases with D-IBS and 24 with C-IBS, and 52 control subjects were collected in the study. Their thermal pain hypersensitivity were examined Thermal stimuli were delivered using a Medoc Thermal Sensory Analyzer with a 3 cm 3 cm surface area. Heat pain threshold (HPTh) and heat pain tolerance (HPTo) were assessed on the left ventral forearm and left calf using an ascending method of limits. The Functional Bowel Disease Severity Index (FBDSI) was also obtained for all subjects.

The research revealed controls were less sensitive than C-IBS and D-IBS with no differences between C-IBS and D-IBS for HPTh and HPTo. Thermal hyperalgesia was present in both groups of IBS patients relative to controls, with IBS patients reporting significantly lower pain threshold and pain tolerance at both test sites.

A unique finding of this study is that the authors detected a strong relationship between heat pain measures and Functional Bowel Disease Severity Index (FBDSI) scores. IBS patients with high FBDSI scores had the highest thermal pain sensitivity compared to those IBS patients with low to moderate FBDSI scores.


'/>"/>

Contact: Lai-Fu Li
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. Converting adult somatic cells to pluripotent stem cells using a single virus
2. Quality of life: most important predictor of survival for advanced NSCLC patients
3. Biomarker may be an early predictor of advanced breast cancer
4. Possible genetic predictor for response to lithium augmentation in depressed patients
5. Predictors of inaccurate online breast cancer information
6. Disability Stronger Predictor of Longevity Than Disease Is
7. Body image is stronger predictor of health than obesity, says Mailman School of PH study
8. OHSU cancer institute researcher discovers new predictor of prostate cancer recurrence
9. UT Southwestern researchers investigate predictors for sickle-cell-anemia complications
10. Leicester medical team announces predictor for pregnant women who may have miscarriages
11. MRI Can Be Predictor of Post-Treatment Prostate Cancer Spread
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... Washington, D.C. (PRWEB) , ... February 08, 2016 ... ... has officially launched its newly redesigned website, federallabs.org . The site houses ... technologies or license available federal technologies through the process called technology transfer (T2). ...
(Date:2/8/2016)... Houma, LA (PRWEB) , ... February 08, 2016 ... ... Louisiana from offices in Houma, LA, celebrates the beginning of a new charity ... raised to assist Court Appointed Special Advocates (CASA). In the belief that children ...
(Date:2/8/2016)... ... February 08, 2016 , ... Brenton Engineering , ... bags, and flow wrapped products at WestPack 2015, February 9-11, in Anaheim, California. ... up to semi-automatic or fully-automatic case packing with a small footprint, rugged, highly ...
(Date:2/8/2016)... ... February 08, 2016 , ... Steve Helwig & Associates Insurance ... new community enrichment program, has teamed up with Citizens Opposed to Domestic Abuse in ... intimate abuse. To support all those victimized by the fear of violence in their ...
(Date:2/8/2016)... ... February 08, 2016 , ... Delta Dental of California and its affiliated ... , Gary D. Radine, who recently retired as president and CEO of Delta Dental ... 2015 CEO of the Year , helped lead the effort to raise funds for ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)...  Patients in Alabama seeking prostate ... no longer have to travel out of state. Vituro ... Urology Centers of Alabama to provide a total prostate ... patients. Alabama is known ... prostate cancer using many different modalities. They are the largest ...
(Date:2/5/2016)...  Venice,s newest laser clinic, Physicians Advanced ... kind in the area and specializes in the ... The physician-owned and operated laser clinic is taking ... with its revitalizing skin care approach, unprecedented eVisit ... technology. http://photos.prnewswire.com/prnh/20160204/329957 --> ...
(Date:2/5/2016)... --> --> ... (Labor & Delivery) and Neonatal Care Equipment Market Ultrasound, ... Phototherapy/Jaundice Management Devices, CPAP, Capnograph, & Resuscitator) - Global ... the global market over the forecast period of 2015 ... Billion in 2015 and is poised to grow at ...
Breaking Medicine Technology: