Navigation Links
Is acetazolamide effective and safe for preventing acute mountain sickness?
Date:7/12/2012

New Rochelle, NY, July 12, 2012 Although acetazolamide is widely prescribed to prevent and treat acute mountain sickness (AMS), the appropriate dose at which it is effective and safe has not been clearly defined. A comprehensive review and meta-analysis of 24 studies comparing the efficacy and risks associated with increasing doses of acetazolamide is published in High Altitude Medicine & Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com). The article is available free online at the High Altitude Medicine & Biology (http://www.liebertpub.com/ham) website.

Bengt Kayser and colleagues, University of Geneva, Switzerland, reviewed the data compiled on more than 1,000 subjects and describe the relationship between efficacy in preventing and treating AMS, risk of side effects, and increasing drug dosages. They discuss their findings in the article "Reappraisal of Acetazolamide for the Prevention of Acute Mountain Sickness: A Systematic Review and Meta-Analysis (http://online.liebertpub.com/doi/full/10.1089/ham.2011.1084)."

Unless the baseline risk of AMS is high, as with rapid transport to high altitude (as opposed to a slow ascent), acetazolamide has limited effectiveness. Some side effects occur with even the lowest doses of the drug, whereas others appear to be dose-dependent. The authors suggest that treatment be tailored for the individual depending on AMS risk and acceptability of the most common side effects such as increased urination, numbness and tingling, and taste disturbance.

"This is a valuable contribution on the pros and cons of using the most important medication for preventing and treating acute mountain sickness," says John B. West, MD, PhD, Editor-in-Chief of High Altitude Medicine & Biology and Professor of Medicine at the University of California, San Diego School of Medicine.


'/>"/>
Contact: Cathia Falvey
cfalvey@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Related medicine news :

1. HIV Prevention Pill Cost-Effective for High-Risk Men: Study
2. Pig stomach mucins are effective as anti-viral agents for consumer products
3. Lower-Dose Radioiodine Effective Against Thyroid Cancer
4. Aspirin as Effective as Warfarin for Heart Failure: Study
5. Mayo Clinic: Exhaustion renders immune cells less effective in cancer treatment
6. Breast cancer effectively treated with chemical found in celery, parsley by MU researchers
7. Researchers make promising discovery in pursuit of effective lymphoma treatments
8. Breast MRI helps predict chemotherapys effectiveness
9. Kitchen exhaust fans vary in effectiveness in reducing indoor air pollution
10. New drug found effective against rare form of basal cell skin cancer
11. New Drug Effective for Rare Genetic Skin Cancer: Studies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Is acetazolamide effective and safe for preventing acute mountain sickness?
(Date:5/4/2016)... ... ... May kicked off with Melanoma Monday , a multi-agency effort to raise ... encouraging her patients, as well as residents all around Dallas, Cleburne, Irving, and Plano, ... in the future. , The dermatology-specific awareness month ends with “Don’t Fry Day,” established ...
(Date:5/4/2016)... ... May 04, 2016 , ... Momsense, Inc. ... The company’s patented technology, The Smart Breastfeeding Meter, is designed to monitor and ... technology is now available for purchase at Target.com . , Breastfeeding ...
(Date:5/4/2016)... ... May 04, 2016 , ... Francesca Loparco, Co-Founder of ... life forever with a same-day LASIK procedure at Christenbury Eye Center. The ... Jonathan Christenbury performed her surgery the same day as her in-office consultation and eye ...
(Date:5/4/2016)... ... May 04, 2016 , ... The preeminent surgical aftercare facility Pearl Recovery ... breast cancer surgery. In March 2016, the 61-year-old model and reality TV star was ... occurs in the milk ducts, according to an interview with the Daily Mail ...
(Date:5/4/2016)... ... May 04, 2016 , ... AudioEducator is the ... In upcoming months, AudioEducator has lined up some informative training session for the ... give complete compliance know-how and practical, easy-to-apply advice. , On Thursday, May 19, ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... , May 4, 2016 ... addition of the  "Global Acute Myeloid Leukemia ...  report to their offering.       ... Acute Myeloid Leukemia Market and Competitive Landscape ... Myeloid Leukemia pipeline products, Acute Myeloid Leukemia ...
(Date:5/3/2016)... 4, 2016 Research and Markets ... Stem Cell Therapy Market Outlook 2020" report to ... ) , ,Recombinant technology has improved significantly in past ... be developed in coming years. Many cancer drugs have ... cell therapies are also expected to be developed with ...
(Date:5/3/2016)... , May 3, 2016  While you may be familiar with watching a film or ... also known as ultra-high-definition or 8MP in the Medical Industry.  Ampronix  is a renowned authorized ... innovative technology. Photo - http://photos.prnewswire.com/prnh/20160502/362730 ... ... ...
Breaking Medicine Technology: