Navigation Links
Is acetazolamide effective and safe for preventing acute mountain sickness?
Date:7/12/2012

New Rochelle, NY, July 12, 2012 Although acetazolamide is widely prescribed to prevent and treat acute mountain sickness (AMS), the appropriate dose at which it is effective and safe has not been clearly defined. A comprehensive review and meta-analysis of 24 studies comparing the efficacy and risks associated with increasing doses of acetazolamide is published in High Altitude Medicine & Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com). The article is available free online at the High Altitude Medicine & Biology (http://www.liebertpub.com/ham) website.

Bengt Kayser and colleagues, University of Geneva, Switzerland, reviewed the data compiled on more than 1,000 subjects and describe the relationship between efficacy in preventing and treating AMS, risk of side effects, and increasing drug dosages. They discuss their findings in the article "Reappraisal of Acetazolamide for the Prevention of Acute Mountain Sickness: A Systematic Review and Meta-Analysis (http://online.liebertpub.com/doi/full/10.1089/ham.2011.1084)."

Unless the baseline risk of AMS is high, as with rapid transport to high altitude (as opposed to a slow ascent), acetazolamide has limited effectiveness. Some side effects occur with even the lowest doses of the drug, whereas others appear to be dose-dependent. The authors suggest that treatment be tailored for the individual depending on AMS risk and acceptability of the most common side effects such as increased urination, numbness and tingling, and taste disturbance.

"This is a valuable contribution on the pros and cons of using the most important medication for preventing and treating acute mountain sickness," says John B. West, MD, PhD, Editor-in-Chief of High Altitude Medicine & Biology and Professor of Medicine at the University of California, San Diego School of Medicine.


'/>"/>
Contact: Cathia Falvey
cfalvey@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Related medicine news :

1. HIV Prevention Pill Cost-Effective for High-Risk Men: Study
2. Pig stomach mucins are effective as anti-viral agents for consumer products
3. Lower-Dose Radioiodine Effective Against Thyroid Cancer
4. Aspirin as Effective as Warfarin for Heart Failure: Study
5. Mayo Clinic: Exhaustion renders immune cells less effective in cancer treatment
6. Breast cancer effectively treated with chemical found in celery, parsley by MU researchers
7. Researchers make promising discovery in pursuit of effective lymphoma treatments
8. Breast MRI helps predict chemotherapys effectiveness
9. Kitchen exhaust fans vary in effectiveness in reducing indoor air pollution
10. New drug found effective against rare form of basal cell skin cancer
11. New Drug Effective for Rare Genetic Skin Cancer: Studies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Is acetazolamide effective and safe for preventing acute mountain sickness?
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Dr. Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile ... orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can ...
(Date:6/24/2016)... ... , ... People across the U.S. are sharpening their pencils and honing their ... in which patients and their families pay tribute to a genetic counselor by nominating ... of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Grove Investment Group (TGIG), has initiated cultivation and processing operations at its production ... and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system of ...
(Date:6/24/2016)... Washington, D.C. (PRWEB) , ... June 24, 2016 , ... ... Pro-Am Heroes Golf Classic Tournament held on June 20th at the Woodmont Country ... local charity, Luke’s Wings, an organization dedicated to helping service members that have been ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Bracket , ... launch its next generation clinical outcomes platform, Bracket eCOA (SM) ... held on June 26 – 30, 2016 in ... first electronic Clinical Outcome Assessment product of its kind to ... #715. Bracket eCOA 6.0 is a flexible platform ...
(Date:6/23/2016)... BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), ... company,s second affiliate in Latin America . ... ... Colombia ... ...
(Date:6/23/2016)... 23, 2016 The vast majority of dialysis ... facility.  Treatments are usually 3 times a week, with ... including travel time, equipment preparation and wait time.  This ... grueling for patients who are elderly and frail.  Many ... and rehabilitation centers for some duration of time. ...
Breaking Medicine Technology: