Navigation Links
Is acetazolamide effective and safe for preventing acute mountain sickness?
Date:7/12/2012

New Rochelle, NY, July 12, 2012 Although acetazolamide is widely prescribed to prevent and treat acute mountain sickness (AMS), the appropriate dose at which it is effective and safe has not been clearly defined. A comprehensive review and meta-analysis of 24 studies comparing the efficacy and risks associated with increasing doses of acetazolamide is published in High Altitude Medicine & Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com). The article is available free online at the High Altitude Medicine & Biology (http://www.liebertpub.com/ham) website.

Bengt Kayser and colleagues, University of Geneva, Switzerland, reviewed the data compiled on more than 1,000 subjects and describe the relationship between efficacy in preventing and treating AMS, risk of side effects, and increasing drug dosages. They discuss their findings in the article "Reappraisal of Acetazolamide for the Prevention of Acute Mountain Sickness: A Systematic Review and Meta-Analysis (http://online.liebertpub.com/doi/full/10.1089/ham.2011.1084)."

Unless the baseline risk of AMS is high, as with rapid transport to high altitude (as opposed to a slow ascent), acetazolamide has limited effectiveness. Some side effects occur with even the lowest doses of the drug, whereas others appear to be dose-dependent. The authors suggest that treatment be tailored for the individual depending on AMS risk and acceptability of the most common side effects such as increased urination, numbness and tingling, and taste disturbance.

"This is a valuable contribution on the pros and cons of using the most important medication for preventing and treating acute mountain sickness," says John B. West, MD, PhD, Editor-in-Chief of High Altitude Medicine & Biology and Professor of Medicine at the University of California, San Diego School of Medicine.


'/>"/>
Contact: Cathia Falvey
cfalvey@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Related medicine news :

1. HIV Prevention Pill Cost-Effective for High-Risk Men: Study
2. Pig stomach mucins are effective as anti-viral agents for consumer products
3. Lower-Dose Radioiodine Effective Against Thyroid Cancer
4. Aspirin as Effective as Warfarin for Heart Failure: Study
5. Mayo Clinic: Exhaustion renders immune cells less effective in cancer treatment
6. Breast cancer effectively treated with chemical found in celery, parsley by MU researchers
7. Researchers make promising discovery in pursuit of effective lymphoma treatments
8. Breast MRI helps predict chemotherapys effectiveness
9. Kitchen exhaust fans vary in effectiveness in reducing indoor air pollution
10. New drug found effective against rare form of basal cell skin cancer
11. New Drug Effective for Rare Genetic Skin Cancer: Studies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Is acetazolamide effective and safe for preventing acute mountain sickness?
(Date:1/16/2017)... ... 2017 , ... Permobil has just completed the acquisition of ... systems has a well-earned reputation for premium quality, with a focus on fit ... in the custom seating business, which enjoys strong demand, and it complements Permobil’s ...
(Date:1/16/2017)... ... January 16, 2017 , ... ... teacher, http://www.ageofautism.com/legal , Sharon Kleyne, America’s leading water educator, researcher and ... nationally syndicated radio program, The Sharon Kleyne Hour Power of Water, Global Climate ...
(Date:1/16/2017)... ... January 16, 2017 , ... San Francisco dentist, Dr. Ben ... in 3-D scanning device which is capable of taking digital impressions of teeth and ... such as CAD CAM restorations , in terms of speed, efficiency and patient ...
(Date:1/15/2017)... ... 15, 2017 , ... Going above and beyond the practical ... better communities around the world by offering the Gensuite team and their services ... team members to become involved in a cause that is bigger than themselves ...
(Date:1/15/2017)... ... January 15, 2017 , ... ... physicians in eight Bay Area counties for 2017. Almost 1,000 nominations were submitted ... managing the award process. Results were announced the magazine’s January 2017 issue ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... Jan. 16, 2017  An aneurysm develops due to the ... Aneurysms can occur in any artery, it happens ... that supplies blood to legs. Most aortic aneurysms occur in ... and are referred as abdominal aortic aneurysms, sometimes in the ... the aorta in the abdomen is about 2 cm but ...
(Date:1/16/2017)... ® Inc., a leading manufacturer and marketer of imaging and ... Spectrum TM Single-Use video laryngoscopes. The new Spectrum ... Reduction TM technology, which actively optimizes image quality. ... ... Introducing another bright idea from GlideScope(R) Video Laryngoscopes: ...
(Date:1/16/2017)... 16, 2017  According to Kalorama Information, the ... valued at $4.9 billion for 2016.  The growing ... an aging population with significant diagnostic needs, along ... propelling the market for the modality.  The healthcare ... , focuses on the worldwide market, providing market ...
Breaking Medicine Technology: