Navigation Links
Ireland Cancer Center researcher finds standard treatment for breast cancer not followed
Date:12/21/2007

Research out of the Ireland Cancer Center of University Hospitals Case Medical Center, in collaboration with six integrated health plans that are part of the Cancer Research Network, found that the majority of older women with early stage breast cancer fail to adhere to the standard of treatment five years of daily oral use of the chemo-prevention drug Tamoxifen. To be published in the February issue of Journal of Clinical Oncology and released earlier this month, Cynthia Owusu, MD, of the Ireland Cancer Center (ICC) and colleagues determined that premature tamoxifen discontinuation is quite common and deserves closer attention.

We in the medical community have long believed we were caring for these women appropriately and this study determines that these patients over age 65 are being woefully undertreated, said Dr. Owusu, who runs the ICCs geriatric oncology program and was lead author of the study. Going forward we need to develop strategies to improve breast cancer outcomes for these women.

The study looked at 961 women over the age of 65 who had early stage hormone positive breast cancer. Previous research has shown that five years of Tamoxifen is more effective than two years of use. However, information on tamoxifen discontinuation has been scanty. Dr. Owusu and her group sought to identify factors that predict premature tamoxifen continuation.

They found that nearly 50% of the women in the study discontinued tamoxifen before the completion of five years. The women most likely to stop taking the treatment were women over age 75, women who developed other medical illnesses during the first three years of follow-up and those who had their breast lumps removed but failed to receive radiation after their surgery. The discontinuation of Tamoxifen may result in earlier recurrences, and ultimately, increased breast cancer mortality.

This study is the first to show that closer attention to non-adherence among older women
'/>"/>

Contact: Alicia Reale
Alicia.Reale@UHhospitals.org
216-844-5158
University Hospitals of Cleveland
Source:Eurekalert

Page: 1 2

Related medicine news :

1. University Hospitals Ireland Cancer Center and Funky Winkerbean Cartoonist Tom Batiuk Establish Lisas Legacy Fund for Cancer Research and Education
2. Carrington Subsidiary DelSite to Present at International Vaccine Conference in Ireland
3. PulseLearning (Founded in Childs Bedroom in an Irish Suburban Semi Eight Years Ago and Initially Run on a Second-Hand Computer) Today Named Fastest Growing IT Company in Ireland
4. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
5. Survival differences by race most apparent in advanced stages of breast cancer
6. MRI finds breast cancer before it becomes dangerous
7. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
8. Pathway links inflammation, angiogenesis and breast cancer
9. Radiologists encouraged to look beyond cancer for clinically unseen diseases
10. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
11. Immune deficiency linked to a type of eye cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... Hills, CA (PRWEB) July 12, 2014 For ... why are bodies can readily absorb the nutrients in food. ... tiny particles that are small enough to be absorbed by ... DZ10 team, a lack of enzymes in regular food is ... is a product that was started by Michelle DelPresto, a ...
(Date:7/12/2014)... July 12, 2014 “Critical Care ... New and Late-Stage Four-Factor PCCs and Recombinant Products ... the critical care market in the US, UK, ... report provides an estimation of market size for ... covers critical care indications that are being treated ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 As reported in ... Institute of Standards and Technology), the June 25th, 2014 Supreme ... electronic discovery world. It was also met with ... depending on whether it was seen from an individual privacy ... much is fact, there is now precedent which will require ...
(Date:7/12/2014)... Dubai is buzzing with the announcement ... to the UAE. The National Basketball Association’s (NBA) ... the UAE from 28-31 October to lead the Kareem ... awareness. The event is being organized by Maven Marketing ... company based in Dubai. The announcement was made today ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 Praeclarus ... Made Simple as a valuable new resource for women ... two-thirds of American women work away from their children. ... touting the benefits of breastfeeding, but often feel unsupported ... nurse their babies. With its evidence-based insights, and written ...
Breaking Medicine News(10 mins):Health News:New Super Digestive Enzyme, DZ10, Supercharges The Digestion Process 2Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 2Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 3Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 4Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 5Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 6Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 2Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 3Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 4Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 5Health News:Los Angeles Basketball Legend Headed to Dubai 2Health News:Los Angeles Basketball Legend Headed to Dubai 3Health News:Praeclarus Press Announces the Release of Working and Breastfeeding Made Simple by Nancy Mohrbacher, A Much Needed Resource For Today's Working Mothers 2
... fertility law so that couples in UK can choose the ... UK government highlighted more than 70 fertility issues on Tuesday ... update of the 1990 Human Fertilization and Embryology Act. The ... law which allows scientists to alter the genes of future ...
... or those who have long working hours face increased risk ... is. Infact employees who work overtime were 61 percent ... those who didn't. ,Previous studies had established a ... certain occupations, industries or companies. It has been for the ...
... disorders like rheumatoid arthritis may be reduced by ... carrots and sweetcorn. //, ,Vitamin C and ... in brightly-coloured fruit and veg, may act as ... damage and inflammation. ,The levels of intake ...
... of the hospitals may face an increased risk of medical ... August issue // of Critical Care Medicine., ,Researchers found ... intensive care units at an academic hospital, a medical intensive ... experienced an adverse event. Because these patients are among the ...
... produced from Human embryonic stem cells by Researchers from University ... to produce the required cell type. The nerve stem cells ... // The new nerve stem cells can be used ... ,The university's Dr Steven Pollard said: "This is incredibly exciting ...
... wearing high protection sunscreen lotions may be better protected ... published the research report in the topic // . ... involved in the development of skin cancer, says the ... has been shown to prevent squamous cell skin carcinoma, ...
Cached Medicine News:Health News:All Work And No Play Makes Jack A Dull Boy 2Health News:Sunscreen Lotions Offering High Protection May Be Better Than Usual Sunscreens 2
(Date:7/10/2014)... July 10, 2014  The U.S. Department of Health ... to University Hospitals (UH) Case Medical Center Seidman Cancer ... model aimed at improving care for patients with complex ... project will test a unique model developed at UH ... disease, significant comorbidities, or demonstrated need for high health ...
(Date:7/10/2014)... JORDAN, Utah , July 10, 2014  BC ... solutions, and MiE America , Inc., a leading ... have entered into a long-term agreement naming BC Technical ... the US. MiE and BC Technical ... strategic agreement to establish BC Technical as the service ...
(Date:7/10/2014)... July 10, 2014 CVS Caremark Corporation (NYSE: ... has approved a quarterly dividend of $0.275 (27.5 cents) per ... on August 1, 2014, to holders of record on July ... CVS Caremark is dedicated to helping people on their path ... the United States . Through the company,s ...
Breaking Medicine Technology:University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4BC Technical Partners With MiE America To Be Authorized Provider Of Systems & Service 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: