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Investigators from Children's Hospital LA honored
Date:12/7/2010

LOS ANGELES (December 7, 2010) Three investigators from The Saban Research Institute of Children's Hospital Los Angeles have been elected into the prestigious Society for Pediatric Research. Their election to this Society represents peer recognition of their research achievements in pediatrics.

The Society for Pediatric Research exists to foster the research and career development of investigators engaged in creating new knowledge that advances the health and well‐being of young people. Membership is by election only.

Steven Mittelman, MD, PhD, conducts his research at the Center for Endocrinology, Diabetes and Metabolism at Children's Hospital Los Angeles, and is an assistant professor of Pediatrics, Physiology, and Biophysics at the Keck School of Medicine of the University of Southern California.

"Being overweight impairs our ability to treat a patient's leukemia, the most common cancer occurring in children," explains Dr. Mittelman. "We've found that fat cells secrete chemical messengers that cause leukemia cells to migrate into the fat. Fat cells also secrete factors that protect leukemia cells from chemotherapy, making the disease more difficult to treat."

Leo Mascarenhas, MD, MS, is director of the Clinical Trials Office in the Children's Center for Cancer and Blood Diseases and Principal Investigator for the National Cancer Institute funded Children's Oncology Group grant at Children's Hospital Los Angeles. He is an associate professor of Clinical Pediatrics at the Keck School of Medicine of the University of Southern California.

"Childhood cancer is the leading cause of disease-related death in pediatrics in the United States," says Dr. Mascarenhas whose research focuses on developmental therapeutics for patients with bone and soft tissue sarcomas. "Despite the remarkable progress made in the treatment of childhood cancer in the last four decades, improved therapies are still needed for our patient
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Contact: Ellin Kavanagh
ekavanagh@chla.usc.edu
323-361-8505
Children's Hospital Los Angeles
Source:Eurekalert

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