Navigation Links
Investigational urine test can predict high-risk prostate cancer in men who chose 'watchful waiting'
Date:2/2/2012

SEATTLE Initial results of a multicenter study coordinated by researchers at Fred Hutchinson Cancer Research Center indicates that two investigational urine-based biomarkers are associated with prostate cancers that are likely to be aggressive and potentially life-threatening among men who take a "watchful waiting," or active-surveillance approach to manage their disease. Ultimately, these markers may lead to the development of a urine test that could complement prostate biopsy for predicting disease aggressiveness and progression.

Study principal investigator Daniel Lin, M.D., an associate member of the Hutchinson Center's Public Health Sciences Division, will present these findings today at the 2012 Genitourinary Cancers Symposium of the American Society of Clinical Oncology in San Francisco.

"Prostate biopsies are invasive and don't always pick up all of the cancer. Post-digital-rectal exam urine collection is much less invasive. If a urine-based diagnostic test could be developed that could help predict aggressive disease or disease progression, that would be ideal," said Lin, who is also an associate professor and chief of urologic oncology at the University of Washington Department of Urology.

Lin leads a nationwide consortium of eight institutions called the Canary Prostate Active Surveillance Study, an endeavor dedicated to identifying and validating biomarkers of high-risk prostate cancer.

Because many prostate cancers are slow growing and never become life threatening, many men with early stage prostate cancer choose active surveillance delaying treatment while closely monitoring to see whether the cancer progresses.

Two urine-based biomarkers were found to correlate with indicators of aggressive disease: tumor volume (the number of biopsy samples that contain cancer) and Gleason score (predicting the aggressiveness of cancer by how it looks under a microscope). The markers that mirrored these correlates of disease aggressivenes
'/>"/>

Contact: Kristen Lidke Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Scott & White Healthcare researchers studying investigational agent that targets breast cancer
2. Pivotal data for the investigational treatment PSD502 for primary premature ejaculation
3. New investigational compound targets pancreatic cancer cells
4. Investigational eye treatment: Corneal collagen crosslinking research study
5. Cancer-targeting investigational nanoparticle receives FDA IND approval for first-in-human trial
6. Incisionless surgery now available as an investigational treatment for esophageal disorder
7. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
8. Urine test for kidney cancer a step closer to development
9. Moving Closer to a Urine Test for Colon Cancer
10. Autism finding could lead to simple urine test for the condition
11. Color, Odor Changes in Urine Usually -- But Not Always -- Harmless, Reports Harvard Women's Health Watch
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/21/2014)... The number of Mirena lawsuits ( ... underway in New Jersey, Bernstein Liebhard LLP reports. , ... involving the birth control IUD have now been filed ... by women who allege spontaneous migration of the device, ... and other complications they were inadequately warned about by ...
(Date:12/21/2014)... OR (PRWEB) December 21, 2014 ... some of the issues and systemic barriers for disabled ... World Paratriathlon Champion. Scheidies has a condition called juvenile ... time. He describes how he adapted his athletic ambitions ... use his success in triathlon to pioneer the way ...
(Date:12/21/2014)... Concept Plus, LLC. a SDB and 8(a) certified IT ... today announced it has been recognized by Washington Technology as ... fastest growing government contracting small businesses by calculating their compound ... the first year that Concept Plus, LLC., participated in the ... compound annual growth rate. “For Concept Plus to be recognized ...
(Date:12/20/2014)... York, NY (PRWEB) December 20, 2014 ... the healthcare sector have benefited the Massage Services ... the discretionary characteristics of industry products, the anticipated 1.0% ... five-year period has provided consumers with the means to ... that have received a massage in a given year ...
(Date:12/20/2014)... Recently, VogueQueen.com, a leading wedding dress wholesaler and ... for 2015. Great discounts are now offered on ... can get a discount, up to 80% off, when ... January 30, 2015. , VogueQueen.com has recently released its ... dress promotion. Many customers worldwide like VogueQueen’s special designs ...
Breaking Medicine News(10 mins):Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 3Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 2Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 3Health News:Concept Plus, LLC. Named One of Washington Technology’s Fast 50 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:VogueQueen Big Sale Online For The Coming 2015 2
... DC & PARIS, FRANCE The International Union ... for Public Health Education (SOPHE) are pleased to release ... strengthening standards and quality assurance systems of global capacity ... Health Education & Behavior (Vol. 36, No. ...
... MDThe American Institute of Ultrasound in Medicine is pleased ... Second Edition . All operators of ultrasound systems with ... publication. The book consists of 3 parts: Bioeffects and ... reasonably achievable). With the information from this 64 page ...
... Inc. (Nasdaq: NYER ) reported results for the ... third quarter of fiscal 2009 increased $1.3 million or 7.5% ... comparable quarter in the prior year. The increase in ... pharmacies over the past 12 months. Revenues slightly decreased ...
... spot anti-inflammatory components in the traditional remedy , , ... been used in medicine for centuries, and now ... new study has found that the herb, which ... medicine, fights inflammation. , Researchers from the University ...
... study techniques identify anti-inflammatory components in ginseng , , ... been used in medicine for centuries, and now ... new study has found that the herb, which ... medicine, fights inflammation. , Researchers from the University ...
... - Researchers at Boston University School of Medicine ... Gram-negative rods (GNRs) in two of the largest ... of Manila, Philippines. Improved infection control methods could ... infections. The BUSM study appears online in the ...
Cached Medicine News:Health News:Special journal issues released on global health promotion and health education 2Health News:AIUM releases second edition of 'Medical Ultrasound Safety' 2Health News:Nyer Medical Group, Inc. Reports Revenues of $18.6 Million for the Quarter Ended March 31, 2009 2Health News:Nyer Medical Group, Inc. Reports Revenues of $18.6 Million for the Quarter Ended March 31, 2009 3Health News:Nyer Medical Group, Inc. Reports Revenues of $18.6 Million for the Quarter Ended March 31, 2009 4Health News:Nyer Medical Group, Inc. Reports Revenues of $18.6 Million for the Quarter Ended March 31, 2009 5Health News:New Insights Show Ginseng Fights Inflammation 2Health News:New Discovery Shows Ancient Herb Fights Inflammation 2Health News:BUSM researchers find gram-negative rods in two Philippine neonatal intensive care units 2
(Date:12/17/2014)... and SAN DIEGO , Dec. ... PHG ; AEX: PHIA) and Volcano Corporation (NASDAQ: ... measurement solutions for cardiovascular applications, today announced that they have ... Philips will commence a tender offer to acquire all of ... per share, or a total equity purchase price of USD ...
(Date:12/17/2014)... NASHVILLE, Tenn. , Dec. 17, 2014  Strategic ... health management software solutions, today announced a strategic agreement ... the New Jersey regional marketplace.  ... and enhance the health and wellness solutions QualCare brings ... and the surrounding region. QualCare ...
(Date:12/17/2014)... SCOTTSDALE, Ariz. , Dec. 17, 2014 /PRNewswire/ ... of state-of-the-art interactive music products, today announced that ... Ltd, a leading manufacturer and supplier of innovative ... As part of the agreement, RSL ... Facility bundled solution specifically configured for use within ...
Breaking Medicine Technology:Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 2Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 3Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 2Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 3
... LITTLE FALLS, N.J., Nov. 5 CANTEL MEDICAL CORP. ... Krakauer, President & CEO, will be presenting at the Sidoti ... formal presentation is scheduled for 9:05 AM ET on Friday, ... a Q & A session immediately following the presentation. In ...
... Sunesis Pharmaceuticals, Inc. (Nasdaq: SNSS ) today announced ... voreloxin orphan drug designation for the treatment of acute ... 2 clinical trials of voreloxin in AML: a single-agent ... elderly AML patients unlikely to benefit from standard induction ...
Cached Medicine Technology:Sunesis' Voreloxin Receives FDA Orphan Drug Designation for Acute Myeloid Leukemia 2Sunesis' Voreloxin Receives FDA Orphan Drug Designation for Acute Myeloid Leukemia 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: