Navigation Links
Investigational eye treatment: Corneal collagen crosslinking research study
Date:9/20/2010

Teaneck, NJ The Cornea and Laser Eye Institute, with Principal Investigator, Peter S. Hersh M.D., is conducting a research study to study the safety and effectiveness of corneal collagen crosslinking (CXL) using Riboflavin/Dextran and Hypotonic Riboflavin in patients with progressive keratoconus and corneal ectasia.

Keratoconus is a disease of the cornea, the clear front lens of the eye (like the crystal on a watch), that occurs in the overall population at a rate of about one in 2000. It usually begins in the teens and 20's and can worsen over time. It is often discovered when vision cannot be properly corrected with glasses. Keratoconus results in thinning of the corneal tissues. Consequently, the cornea bulges out of its smooth, clear, dome-like structure, and assumes a more conical and irregular configuration. Because of this change in shape, the cornea loses its ability to form a clear image in the eye and the patient's vision can decrease drastically. Treatments include specialty keratoconus contact lenses and corneal inlays. However, the keratoconus cornea can continue to bulge over time and some keratoconus patients ultimately may require corneal transplantation to regain vision.

Corneal collagen crosslinking (CXL) using ultraviolet light combined with riboflavin (Vitamin B2) is an investigational procedure designed to strengthen the cornea and decrease the progression of keratoconus. CXL is an investigational procedure and is not approved for use in the United States. However, here at the CLEI Center for Keratoconus, we are participating in a research study of CXL. The goal of the study is to assess the safety and efficacy of crosslinking for the treatment of keratoconus as well as corneal ectasia after LASIK. If successful, CXL may decrease progression of keratoconus and maintain the patient's vision over time.

During the crosslinking procedure, anesthesia drops are administered. The surface epithelial cells of the cornea are then removed and riboflavin drops are administered for 30 minutes. The riboflavin acts both to enhance the crosslinking effect and to protect the rest of the eye from the UV exposure.

The patient then looks at a UV emitting light for 30 minutes. At the conclusion of the procedure, a soft contact lens bandage is applied. The contact lens is left in place to improve healing for approximately 5 days and is then removed. Antibiotic and anti-inflammatory drops are used for two weeks afterwards.


'/>"/>

Contact: Stacey Lazar
slazar@vision-institute.com
201-883-0505
The Cornea and Laser Eye Institute, P.A.
Source:Eurekalert

Related medicine news :

1. New investigational compound targets pancreatic cancer cells
2. Pivotal data for the investigational treatment PSD502 for primary premature ejaculation
3. Scott & White Healthcare researchers studying investigational agent that targets breast cancer
4. Study finds new key to corneal transplant success
5. Khanna Institute to Provide Intacs Corneal Implants in Beverly Hills
6. Corneal Transplant Not Hurt by Long Preservation Time
7. Collagen manufactured from transgenic tobacco plants at Hebrew University
8. Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update
9. Drug to treat alcoholism goal of UH professors research
10. Mayo-led researchers discover genetic variants modifying breast cancer risk
11. Rutgers researchers discover how HIV resists AZT
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... ... 2016 , ... Washington Wellness Center today announced its tenth anniversary of providing ... started out as an idea to provide a holistic approach to wellness has now ... by Dr. David Swanekamp, Chiropractic Physician , the wellness center offers a complete ...
(Date:5/4/2016)... ... 2016 , ... Dr. Elyson and Dr. Assili, dentist in Northridge , ... tooth removal, a common dental procedure, is performed for many adolescents and young adults ... in risks of complications. By providing wisdom tooth removal surgery at their office, Dr. ...
(Date:5/4/2016)... ... May 04, 2016 , ... Recognizing that lifestyle medicine is essential to health ... have tapped David Katz, MD, MPH, president of the American College of Lifestyle Medicine, ... medicine is especially gratifying,” said Katz. “There is so much opportunity to add years ...
(Date:5/4/2016)... , ... May 04, 2016 , ... ... the pharmacy industry, today announced that it was chosen as the Pharmaceutical News ... Industry Awards . The awards acknowledge the hard work and dedication of community ...
(Date:5/4/2016)... ... May 04, 2016 , ... Advanced Spine & Sport Medical ... its patients’ health, is hosting a free seminar on stem cell injections. The seminar ... Advanced Spine & Sport, 4601 Telephone Road, Suite 110, Ventura, CA. There are only ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... COUNTY, Calif. , May 3, 2016  While you may be familiar with watching a ... resolution , also known as ultra-high-definition or 8MP in the Medical Industry.  Ampronix  is a ... manufacturer of innovative technology. Photo - http://photos.prnewswire.com/prnh/20160502/362730 ... ... ...
(Date:5/3/2016)... Calif. , May 3, 2016  Specialty ... teaching tool that shows how a cleanroom works. ... classroom discussions about science and technology. ... said, "As a technology company, SSF enthusiastically supports ... to help educators foster the next generation of ...
(Date:5/2/2016)... , May 2, 2016 Kalorama Information ... (Electronic Medical Records) market in a recent white paper.  ... switches, Increased physician usage, a growing market are among ... noted in Kalorama,s report EMR 2016: The ... marks Kalorama,s seventh complete study of the EMR industry, ...
Breaking Medicine Technology: