Navigation Links
Investigational Drug May Help Avert Blood Clots
Date:3/13/2009

Researchers say it works even when common blood thinners also are taken

FRIDAY, March 13 (HealthDay News) -- A drug derived from the magnolia tree appears to be safe and tolerable in preventing blood clots, according to a phase 2 study conducted by researchers at the Duke Clinical Research Institute.

The trial included 1,030 people, 45 years and older, who were scheduled to undergo either percutaneous coronary intervention (PCI) -- a procedure to clear clogged arteries and keep them open with stents -- or angiography and then PCI. People having PCI are usually prescribed drugs, such as aspirin or clopidogrel, to prevent potentially dangerous blood clots.

The study participants were randomly assigned to receive one of three doses (10, 20 or 40 milligrams) of the new drug, called SCH 530348, or a placebo. Aspirin and clopidogrel were not prescribed as part of the study but were allowed, and 95 percent of people in the study took both drugs, the researchers said.

They found that the new drug was generally tolerable at all dosing levels and did not increase bleeding, even when taken with aspirin and clopidogrel. Bleeding occurred in 2 percent of the 129 people who took 10 mg, in 3 percent of those who took 20 mg, in 4 percent of those who took 40 mg and in 3 percent of the placebo group.

Participants were also given different maintenance doses of the drug. Bleeding occurred in 2 percent of those who took 0.5 mg, in 4 percent who took 1 mg, in 3 percent who took 2.5 mg and in 2 percent of those who took the placebo.

The findings were released online and published in the March 14 print issue of The Lancet. The study was funded by Schering-Plough, and a number of the study's authors received consulting fees from the drug maker or own stock in the company.

The researchers said that SCH 530348 appears able to uncouple two important functions of thrombin in the formation of blood clots
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Medarex to Receive Milestone Payment from MedImmune for Allowance of an Investigational New Drug Application for MEDI-546
2. PARI Pharma Completes Successful Clinical Trials for Tobramycin 100 & Investigational eFlow for CF
3. Tibotec presents interim findings for TMC435, an investigational genotype 1 hepatitis C treatment
4. Phase 3 Data Indicate Investigational 13-valent Vaccine May Broaden Protection Against Pneumoccocal Disease in Children Younger than Two
5. AUDIO from Medialink and Genzyme: Study in New England Journal of Medicine Shows Investigational Compound Reduced Relapses and Disability in Patients With MS
6. Takedas investigational PPI TAK-390MR demonstrated higher healing rates compared to lansoprazole
7. Arthrosurface HemiCAP(R) Focal Knee Resurfacing Implant Receives FDA Approval to Move into Final Investigational Stage
8. NEW DATA FOR PAZOPANIB - GSKS LATEST INVESTIGATIONAL ANTI-CANCER AGENT - SHOWS PROMISE ACROSS MULTIPLE CANCERS
9. Shire investigational nonstimulant INTUNIV showed significant efficacy in reducing ADHD symptoms
10. UAB study shows investigational drug may treat biliary cancers
11. Investigational anti-restenosis drug pimecrolimus disappoints
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Investigational Drug May Help Avert Blood Clots
(Date:7/3/2015)... ... July 03, 2015 , ... ... on June 25, 2015 at 1:00pm. The Association welcomed speaker C. Daniel McGillicuddy ... injured bicyclists and practical points of investigating these types of cases. , Each ...
(Date:7/3/2015)... ... July 03, 2015 , ... First Choice Emergency Room , ... N. Manzanares, MD as the new Medical Director of its Frisco facility. , “We ... our Frisco facility,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:7/3/2015)... ... 03, 2015 , ... The Celebrity Dresses is currently running a promotion through ... celebrities will have the opportunity to get 10% discount on orders that are over ... not have to use coupon codes or remember redemption codes. , There is ...
(Date:7/2/2015)... ... ... Following the recent report by JAMA Internal Medicine published on ... Samir Becic emphatically declared a war on obesity in the United States. , "Obesity ... must understand the magnitude of this discovery. For that reason, I am declaring, along ...
(Date:7/2/2015)... Vancouver, BC (PRWEB) , ... July 02, 2015 , ... With summer in full swing, ... , Canada is one of the top spots for fishing in the world, and it’s ... and rivers of Ontario, Canada has great fish. , Recreational fishing is a huge ...
Breaking Medicine News(10 mins):Health News:Attorney from William Mattar Leads Discussion on Bicycle Accidents 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 3Health News:Celebrity Fashion Summer Party Dresses on sale at TheCelebrityDresses.com 2Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 2Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 3Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 4
... 3 (HealthDay News) -- The impending extinction of various ... important buffer against the transmission of infectious disease, new ... U.S. National Science Foundation and National Institutes of Health,s ... Environmental Protection Agency, focused on how the loss of ...
... findings will be highly useful to the manufacturing industry ... toothpaste, cosmetics, pharmaceuticals and foodstuffs depends on an understanding ... The research just published in Nature ... of Physics and Astronomy, with collaborators at the University ...
... Nearly a quarter of Americans live in rural areas, which ... and suburban areas. Among the complex causes for this disparity ... areas and almost 4 out of 10 rural residents ... Finding the time, transportation, and financial resources for travel ...
... By Steven Reinberg HealthDay Reporter , THURSDAY, ... can cut your risk for first-time stroke by 80 ... Association and the American Stroke Association. Also, as ... care, ER doctors are in a position to identify ...
... By Steven Reinberg HealthDay Reporter , THURSDAY, Dec. ... Department of Health and Human Services (HHS) has announced its ... including making dents in rates of obesity, smoking and deaths ... People is to try to move the nation to better ...
... From hotel-style room service to massage therapy to magnificent ... a bid to gain market share, especially those in ... in the New England Journal of Medicine , ... hospital care, explaining that how we decide to value ...
Cached Medicine News:Health News:Species Extinctions May Spell Trouble for Human Health 2Health News:Smashing fluids: The physics of flow 2Health News:ALBERT EINSTEIN COLLEGE OF MEDICINE HELPS ADDRESS NEED FOR IMPROVED CANCER CARE IN RURAL AMERICA 2Health News:Lifestyle Key to Preventing Stroke, Guidelines Say 2Health News:U.S. Government Sets New Health Goals for 2020 2Health News:U.S. Government Sets New Health Goals for 2020 3Health News:Hospital perks: How much should hospitals be rewarded for the patient experience? 2
(Date:7/2/2015)... , July 2, 2015 Releases ... ,Friendly Aedes aegypti , , reduced the ... Brazil by 95%, well below the ... (Logo: http://photos.prnewswire.com/prnh/20150630/227348LOGO) , The journal PLOS Neglected ... of Oxitec,s genetically engineered mosquitoes. The results showed that ...
(Date:7/2/2015)... 26, 2015 Research and Markets( ... D Market by Analog, Application, End-User & by Region - ... offering. This market is projected to reach about ... in different applications and rising opportunities in countries such as ... Italy , and Brazil ...
(Date:7/2/2015)... SAN FRANCISCO , July 2, 2015  The ... www.tryloud.com ), the world,s first HIPAA compliant mobile app ... delivery of farm-to-table fresh medical marijuana, announced today that ... Unlike Eaze, Meadow and more than half ... in the last year, Loud Cannabis is unique in ...
Breaking Medicine Technology:Oxitec Mosquito Works to Control Aedes aegypti in Dengue Hotspot 2Oxitec Mosquito Works to Control Aedes aegypti in Dengue Hotspot 3Vitamin D Market by Analog, Application, End-User & by Region - Global Trends & Forecast to 2020: Increasing Recommendation By Doctors & Associations 2Vitamin D Market by Analog, Application, End-User & by Region - Global Trends & Forecast to 2020: Increasing Recommendation By Doctors & Associations 3New Cannabis Delivery App Gets Product to Patient in Under 7 Minutes 2
... Care Affiliates ("SCA") today announced that it will host ... on Monday, November 16, 2009, to discuss its 2009 ... be available approximately an hour following the conclusion of ... ) , Please go to SCA,s ...
... Cardiac Science Corporation (Nasdaq: CSCX ... AED ) and diagnostic cardiac monitoring devices, today announced ... 30, 2009, in line with its previous guidance. The Company ... field product update and a non-cash charge of $44.0 million ...
Cached Medicine Technology:Cardiac Science Announces Third Quarter Results 2Cardiac Science Announces Third Quarter Results 3Cardiac Science Announces Third Quarter Results 4Cardiac Science Announces Third Quarter Results 5Cardiac Science Announces Third Quarter Results 6Cardiac Science Announces Third Quarter Results 7Cardiac Science Announces Third Quarter Results 8Cardiac Science Announces Third Quarter Results 9Cardiac Science Announces Third Quarter Results 10Cardiac Science Announces Third Quarter Results 11Cardiac Science Announces Third Quarter Results 12Cardiac Science Announces Third Quarter Results 13Cardiac Science Announces Third Quarter Results 14Cardiac Science Announces Third Quarter Results 15Cardiac Science Announces Third Quarter Results 16Cardiac Science Announces Third Quarter Results 17Cardiac Science Announces Third Quarter Results 18Cardiac Science Announces Third Quarter Results 19Cardiac Science Announces Third Quarter Results 20
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: