Navigation Links
Invade and conquer: Nicotine's role in promoting heart and blood vessel disease
Date:2/23/2012

ered by chemical insults from high blood sugar, modified low-density lipoproteins (LDL, the "bad cholesterol"), physical stress from high blood pressure, or chemical insult from tobacco smoke. Now nicotine itself appears to remodel key structures in a way that primes and enhances the invasion of smooth muscle lining the vessel wall.

Identifying a possible nicotine-posodome link in the invasion step of plaque formation process suggests a new means of intervening in the process: targeting the cell structures that are changed by nicotine and that promote invasion of the smooth muscle lining the vessel wall. If a therapy could prevent, slow, or reverse that step, it would likely interrupt the plaque-production cycle.

Fatty deposits accumulate in blood vessels beginning as young as age 10 and progress over a person's lifetime. Heart disease results if the deposits continue to build and harden into vessel-clogging plaque. When plaque ruptures, it can block blood flow, starving the heart or brain of oxygen and leading to a heart attack or stroke.

The presentation, "Cigarette smoke and nicotine-induced remodeling of actin cytoskeleton and extracellular matrix by vascular smooth muscle cells," is at 1:45 p.m. on Sunday, Feb. 26, 2012, in the San Diego Convention Center, Hall FGH. ABSTRACT: http://tinyurl.com/73e836j


'/>"/>

Contact: Ellen R. Weiss
eweiss@biophysics.org
240-290-5606
American Institute of Physics
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Border patrol: Immune cells protect body from invaders, according to Penn study
2. How cavity-causing microbes invade heart
3. Chitosan as alternative to growth-promoting antibiotics for ruminants
4. National Nutrition Month Kicks Off with Hottest Celebrity Diet Trend: Fiber -- F-Factor Diet Book Promoting Fiber Soars Up Best-Sellers List
5. Promoting healing by keeping skeletal stem cells young
6. Better Hearing Institute Joins HHS' Office on Women's Health in Promoting National Women's Health Week and Hearing Health
7. FDA Warns Cosmetic Doctor about Promoting Anti-Wrinkle Drug before FDA Approval; Unbiased Information on Skin Care a Precious Resource Says SkinTour.com
8. Hearing Health Key Factor in Men's Overall Health; BHI Joins Men's Health Network in Promoting National Men's Health Month
9. New function of gene in promoting cancer found by VCU researchers
10. Benz wins Kripke Award for promoting women in science, medical careers
11. Polluted air leads to disease by promoting widespread inflammation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... ... August 28, 2015 , ... United Benefit Advisors (UBA), the ... Group as its newest Partner Firm. Founded in 1924 and headquartered in Pittsburgh, ... on their goals. Within the past 10 years, TJS Insurance Group has emerged ...
(Date:8/28/2015)... ... August 28, 2015 , ... The Plaintiffs ... as MDL 2545, Testosterone Replacement Therapy Products Liability Litigation, are in the midst ... custodial files the PSC may receive for corporate employees involved in the production ...
(Date:8/28/2015)... Livermore, CA (PRWEB) , ... August 28, 2015 , ... ... annual Inc. 5000 list, an exclusive ranking of the nation’s fastest-growing private companies. The ... list’s history. With sales growth of 85% over the last three years, PREVENT ranks ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... dating, companionship, and marriage? , MillionaireMatchmakerOnline.net is set up to help quality singles ... active members on the site are rich, gorgeous, well educated, or attractive. , ...
(Date:8/28/2015)... ... August 28, 2015 , ... On October 3, 2015, BethAnn Telford of TeamBT ... of the Grand Canyon with a shared mission: to beat brain cancer. In one ... across the canyon, then up to the South Rim over 21.1 miles and more than ...
Breaking Medicine News(10 mins):Health News:TJS Insurance Group Is Latest Partner Firm To Join United Benefit Advisors 2Health News:TJS Insurance Group Is Latest Partner Firm To Join United Benefit Advisors 3Health News:National Testosterone Lawyers Provide Testosterone Lawsuit MDL Update 2Health News:National Testosterone Lawyers Provide Testosterone Lawsuit MDL Update 3Health News:National Testosterone Lawyers Provide Testosterone Lawsuit MDL Update 4Health News:PREVENT Life Safety Ranks No. 3660 on the 2015 Inc. 5000 With Three-Year Sales Growth of 85% 2Health News:MillionaireMatchmakerOnline.net Collects and Updates Newest Millionaire and Quality Single Profiles on the Page of Millionaire Matchmaker Online Canada. 2Health News:MillionaireMatchmakerOnline.net Collects and Updates Newest Millionaire and Quality Single Profiles on the Page of Millionaire Matchmaker Online Canada. 3Health News:Women Athletes Cross the Grand Canyon to Raise Funds for Brain Cancer Research – October 3rd 2
... , FRIDAY, Nov. 12 (HealthDay News) -- Black Americans ... as flat feet and corns, new research shows. In the ... examined the feet of 1,536 volunteers and found that blacks aged ... the same age to have corns or flat feet. Among ...
... the place all the time--on the sun, on the Earth ... these reactions occur. One family of enzymes, called cytochrome P450s ... We know P450s are important to life of all kinds ... bacteria, but they are of special interest to humans because ...
... FRIDAY, Nov. 12 (HealthDay News) -- Obstructive sleep apnea ... resulting in problems with cognitive functions such as attention ... changes are likely caused by the intermittent oxygen deprivation ... who temporarily stop breathing many times each night. ...
... A Pneumonia Report Card released today by the ... Global Coalition against Child Pneumonia reveals where urgent efforts ... the life-saving interventions that can prevent, protect against and ... world,s leading infectious killer of young children, taking the ...
... , THURSDAY, Nov. 11 (HealthDay News) -- U.S. female veterans ... smoke cigarettes or use illicit drugs, a new study finds. ... abuse prescription drugs, according to the Center for Behavioral ... analysis of 2002 to 2009 data from the annual National ...
... November 11, 2010Yoga has a greater positive effect on a ... of exercise, which may be due to higher levels of ... Journal of Alternative and Complementary Medicine , a peer-reviewed ... available free online. Yoga has been shown ...
Cached Medicine News:Health News:Some Foot Troubles Hit Blacks, Whites More Often 2Health News:Key player in detoxification pathway isolated after decades of searching 2Health News:Sleep Apnea May Shrink Brain's Gray Matter: Study 2Health News:Efforts to combat pneumonia among 15 high-burdened countries fall short of recommended targets 2Health News:Efforts to combat pneumonia among 15 high-burdened countries fall short of recommended targets 3
(Date:8/28/2015)... SEOUL, South Korea , Aug. 28, 2015 /PRNewswire/ ... Chungbuk National University and Dr. Ra from Biostar ... , Confirmed 30% increase of lifespan through multiple ... cognitive function, physical vitality, and life expectancy found ... Researchers in Korea have determined the possibility that adult ...
(Date:8/27/2015)... , Aug. 27, 2015  The Academy of ... and Drug Administration,s (FDA,s) draft guidance and proposed ... and biosimilars, to bear a nonproprietary name with ... been seeking a decision from the FDA on ... health care stakeholders urging the agency to use ...
(Date:8/27/2015)... -- According to a new market research report "Medical ... Bariatric ), Material (Nylon, Padded, Canvas), Usage Type (Disposable, Reusable), End ... the Medical Lifting Sling Market is poised to reach USD 706.0 ... CAGR of 11.4 % from 2015 to 2020. ... T ables and 65 F ...
Breaking Medicine Technology:Korean Researchers Find the Possibility that Adult Mesenchymal Stem Cells (MSCs) May Extend Lifespan 2AMCP Is Disappointed in FDA's Draft Guidance and Proposed Rule Calling for Suffix on Nonproprietary Names of Biological Products 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 3Medical Lifting Sling Market Worth USD 706.0 Million by 2020 4
... 2011 Hurricane Irene came rushing up the East Coast as ... the United States, many states in the Northeast began to worry. ... to hurricanes. Coastal towns from New Jersey all the way up ... York City was one that took steps that had not been ...
... DIEGO, Aug. 30, 2011 ADVENTRX Pharmaceuticals, Inc. (NYSE ... on its planned meetings with the U.S. Food and ... Exelbine (vinorelbine injectable emulsion) Type ... is to discuss the complete response letter regarding the ...
Cached Medicine Technology:Hospitals Evacuated in Preparation for Hurricane Irene with Aid of Pulse Oximeter 2ADVENTRX Provides Update on All Three Pipeline Products 2ADVENTRX Provides Update on All Three Pipeline Products 3ADVENTRX Provides Update on All Three Pipeline Products 4
... A fixed pipette is ... a single volume. Fixed volume ... and advantages as other Finnpipette ... design, Super blow-out (1-40ul), Soft-touch ...
Pipetman F is a fixed-volume, air-displacement pipette. Thirteen robust models cover a large volume range from 2 L to 1000 L, with Gilsons legendary accuracy and precision....
... Finnpipette Focus from Thermo Labsystems ... ergonomics with uncompromising performance. ... offers a custom fit for ... shorter tip cones allow easier ...
... A fixed pipette is ... a single volume. Fixed volume ... and advantages as other Finnpipette ... design, Super blow-out (1-40ul), Soft-touch ...
Medicine Products: