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Interventions to promote repeat breast cancer screening with mammography
Date:6/29/2010

ion, many of the studies were conducted over ten years ago.

The authors concluded that integration of individual behavioral interventions with structural-level changes may create sustainable improvements in adherence to breast cancer screening. But more studies are needed.

"If we are to reap the benefits of mortality reduction from mammography screening, we need a better understanding of the determinants of repeat screening behavior so that we can develop more effective interventions," the authors write.

In an accompanying editorial, Dr. Jeanne Mandelblatt of Georgetown University Medical Center and Diana Buist, PhD, of the Group Health Research Institute at the University of Washington, write that one of the obstacles to defining the most effective interventions for promoting regular mammography adherence is that women may be choosing not to use mammography because of publicity about mis-diagnoses.

"It could be reasonably argued that we should better spend our efforts in discovering better early detection tests rather than continuing to invest in getting a few more women to regularly use a flawed technology," the authors write, adding that proteomics and gene expression profiling methods are two of the tools used to identify potential biomarkers for screening tests.

"It is no longer enough to simply conduct more interventions to understand which work best in motivating individuals to undergo repeat cancer screening," the authors write. "New paradigms, guided by evidence from modeling, novel trials, and new scientific discovery, will be needed to realize the promise of eliminating the burden of cancer."


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Contact: Kristine Crane
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

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