Navigation Links
Interruption of Menstrual Cycle by Chemotherapy Associated with Improved Survival in Early Breast Cancer
Date:6/3/2010

epartment of Human Oncology at Allegheny General Hospital.

Following primary surgery with total mastectomy or lumpectomy plus axillary nodal dissection, a total of 5,351 premenopausal and postmenopausal women with operable, lymph node-positive, early stage breast cancer were enrolled in the clinical trial and randomly assigned to receive either four cycles of doxorubicin and cyclophosphamide followed by four cycles of docetaxel (sequential ACT); four cycles of doxorubicin and docetaxel (doxorubicin-docetaxel); or four cycles of doxorubicin, cyclophosphamide and docetaxel (concurrent ACT).

At a median follow-up of 73 months, eight year overall patient survival was improved in the sequential ACT group (83%) as compared to both the doxorubicin-docetaxel group (79%) and the concurrent ACT group (79%). Eight-year disease free survival (factoring local, regional or distant breast cancer recurrence, second primary cancer or death from any cause before recurrence) was improved in the sequential ACT group (74%) compared to the doxorubicin-docetaxel group (69%) and the concurrent ACT group (69%).

“This trial showed that the sequential administration of ACT in the adjuvant treatment of operable node positive breast cancer provided a significant 17% reduction in mortality over doxorubicin-docetaxel and a clear advantage over both concurrent treatment approaches in terms of disease free survival,” Dr. Wolmark said.

In addition to Drs. Geyer and Wolmark, other AGH oncologists contributing to the study included D. Lawrence Wickerham, MD, AGH surgical oncologist and Associate Chair of the NSABP and Thomas Julian, MD, Associate Director of the AGH Breast Center and a Principal Investigator for the NSABP at AGH.

###

Read the full story at http://www.prweb.com/releases/Chemotherapy/Breast_Cancer/prweb4083994.htm.'/>"/>

Source: PRWeb
Copyright©2010 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Interruptions Make Doctors Lose Track of Tasks
2. Menstrual Cramps May Be Helped by New Drug
3. How to Say Goodbye to Premenstrual Syndrome (PMS) With the Click of a Button - A New Way to Avoid PMS
4. North Carolina Film Student Scores Big in Bicycle Safety Video Contest
5. Former Microsoft Employee Combines Passion For Technology With American Made Chris King Bicycle Parts
6. Motorcycle Cancer Risk and ELF EMF Radiation Invasion of Gastrointestinal Melatonin
7. Kramer Healthcare Technologies' RQi enterprise™ Revenue Cycle Solution Selected by Piedmont Healthcare
8. Motorcycle Fatalities Drop Sharply in U.S.
9. Tuba City Regional Health Care Corporation Selects Stockell Healthcare to Deploy Patient Access and Revenue Cycle Management Solution
10. Brain Cancer Survivor Will Cycle 4,170 Miles Across USA to Outsmart Disease
11. Greenway Medical Technologies Donates Electronic Health Record, Clinical Research and Revenue Cycle Solutions to Northern Kentucky University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... Diego, Calif. (PRWEB) October 30, 2014 ... longer mutually exclusive concepts in the medical-grade skin ... on the development of uniquely potent topical dermatological ... Health System ( http://www.RefinitySkinScience.com ) with patented COSMEDERM®-7 ... available glycolic acid concentrations (50% and 70%) and ...
(Date:10/30/2014)... 30, 2014 Paramount Rx, a full-service ... increasing efforts to help people save money through its ... increase for prescription drugs in the new health care ... resources to bridge the relationship between consumers, businesses and ... biggest challenges people face today with medical costs is ...
(Date:10/30/2014)... HealthDay Reporter , WEDNESDAY, Oct. ... have been identified that appear linked to autism spectrum ... they are on their way to discovering up to ... Autism spectrum disorders include a range of developmental ... behaviors. An estimated one in 68 U.S. children has ...
(Date:10/30/2014)... 30, 2014 Dr. Joseph Furlin MD, a ... for his practices; OB GYN in Melrose Park, IL ... This website contains important information about each of the care ... downloadable patient forms in English and Spanish. The navigation ... pages on the website provide Dr. Furlin’s patients with important ...
(Date:10/30/2014)... FL (PRWEB) October 30, 2014 ... Joint Commission Accredited teleradiology and specialty telemedicine solutions ... in addition to its existing teleradiology services at ... second opinion and expert telemedicine services, to the ... , As a result of this innovative partnership, ...
Breaking Medicine News(10 mins):Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 2Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 3Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 4Health News:Paramount Rx Discount Card Program Provides Valuable Resources in Midst of Current Health Care Reform 2Health News:Paramount Rx Discount Card Program Provides Valuable Resources in Midst of Current Health Care Reform 3Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 2Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 3Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 2Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 3
... Unrealistic, of,Entire White House Tenure, WASHINGTON, Feb. ... Bush Administration,s FY 2009 budget plan, the American,Health ... from the,standpoint of seniors, Medicare-financed nursing facility care, ... in states across,the nation -- which will surely ...
... Pairs of Shoes Symbolizing Deaths Caused by Tobacco,Use in ... the,statewide youth advocacy group H.O.T. (Helping Overcome Tobacco) will,gather ... Capitol Rotunda to,highlight the problem of tobacco use in ... on the steps of the Capitol, representing the,number of ...
... Sheela Sathyanarayana Fails to Disclose Political Activism, ... of a report from the American Academy of ... for Individual Freedom,(CFIF) today criticized the report as ... In addition to the report "conveniently" omitting,well-known scientific ...
... CINCINNATI A multi-institutional study led by researchers at ... insights and a model to help unravel the cause ... lead to disfigurement and in rare cases death by ... researchers said their findings also provide a means for ...
... have blood pressure under control, study finds , , MONDAY, Feb. ... and high blood pressure, black men are least likely to ... risk of life-threatening complications, a new study says. , Among ... men and women were less likely than white men and ...
... Off National Children,s Dental Health,Month With Outreach Events and ... is National,Children,s Dental Health Month. It,s sponsored each year ... families and policymakers,about the critical importance to children of ... in a row, the ADA opened the month with ...
Cached Medicine News:Health News:Bush Budget Represents 'Double Whammy' Hit on U.S. Seniors' Medicare-Financed Nursing Facility Care 2Health News:Conflict of Interest in American Academy of Pediatrics Report 2Health News:Conflict of Interest in American Academy of Pediatrics Report 3Health News:Model found to determine cause, possible treatment of nerve tumors 2Health News:Black Men Most at Risk for Kidney Disease Complications 2Health News:A Reminder to Parents: Early Dental Visits Essential to Children's Health 2Health News:A Reminder to Parents: Early Dental Visits Essential to Children's Health 3
(Date:10/27/2014)... , 27 de octubre de 2014 /PRNewswire/ ... menudo conocida como ardor de estómago, es un ... mundo. [1] La elección de alimentos [2] ... un impacto en los síntomas de la GERD. ... ayudar a las personas a gestionar los síntomas ...
(Date:10/27/2014)... -- In the last few weeks, Ebola has gone from a localized ... a worldwide crisis when a traveler to United States ... nurses were infected. While much of the cable news ... technology, such as electronic health records (EHRs), to help find, combat, ... Healthcare Editor Alison Diana fills in those gaps by ...
(Date:10/27/2014)... Mass. , Oct. 27, 2014  OMNIlife science™, ... billion global hip and knee replacement device market, announced it ... replacement technology at the American Association of Hip and ... Dallas Hotel in Dallas, Texas ... Bronze corporate partner of the organization. ...
Breaking Medicine Technology:Trate los síntomas del reflujo gracias a la Food4GERD App 2Trate los síntomas del reflujo gracias a la Food4GERD App 3Trate los síntomas del reflujo gracias a la Food4GERD App 4EHRs in the Age of Ebola: Discuss on InformationWeek 2EHRs in the Age of Ebola: Discuss on InformationWeek 3OMNIlife science to Exhibit at American Association of Hip and Knee Surgeons 24th Annual Meeting in Dallas November 6-9 2OMNIlife science to Exhibit at American Association of Hip and Knee Surgeons 24th Annual Meeting in Dallas November 6-9 3
... Texas, Nov. 18, 2010 OCuSOFT, Inc., an ... to announce that ZYTAZE™ is now available in ... but are not limited to: Walgreens, CVS, Wal-Mart, ... In an early pilot study, ZYTAZE™ demonstrated marked ...
... FORD, Pa., Nov. 18, 2010 Endo Pharmaceuticals Holdings ... it priced $400 million aggregate principal amount of 7.00% ... of 99.10 percent in connection with its previously announced ... of the Company and will be guaranteed by certain ...
Cached Medicine Technology:Endo Pharmaceuticals Holdings Inc. Announces Pricing of Private Offering of Senior Notes 2
3.5v Standard Ophthalmoscope Set with Convertible Handle and Soft Case. Our Standard Ophthalmoscope Sets feature high-quality instruments, handles, and cases....
High-quality eyecare from the preferred name in diagnostic instruments....
Our 3.5v Streak or Spot Retinoscope Sets feature instruments with the brightest light output in the industry, reliable handles, and convenient cases....
Testing for Strabismus (ocular misalignment) just became easier. By simply placing the StrabismoScope over the patient's eye, the examiner is able to observe the occluded eye directly, but the patien...
Medicine Products: