Navigation Links
Interruption of Menstrual Cycle by Chemotherapy Associated with Improved Survival in Early Breast Cancer
Date:6/3/2010

epartment of Human Oncology at Allegheny General Hospital.

Following primary surgery with total mastectomy or lumpectomy plus axillary nodal dissection, a total of 5,351 premenopausal and postmenopausal women with operable, lymph node-positive, early stage breast cancer were enrolled in the clinical trial and randomly assigned to receive either four cycles of doxorubicin and cyclophosphamide followed by four cycles of docetaxel (sequential ACT); four cycles of doxorubicin and docetaxel (doxorubicin-docetaxel); or four cycles of doxorubicin, cyclophosphamide and docetaxel (concurrent ACT).

At a median follow-up of 73 months, eight year overall patient survival was improved in the sequential ACT group (83%) as compared to both the doxorubicin-docetaxel group (79%) and the concurrent ACT group (79%). Eight-year disease free survival (factoring local, regional or distant breast cancer recurrence, second primary cancer or death from any cause before recurrence) was improved in the sequential ACT group (74%) compared to the doxorubicin-docetaxel group (69%) and the concurrent ACT group (69%).

“This trial showed that the sequential administration of ACT in the adjuvant treatment of operable node positive breast cancer provided a significant 17% reduction in mortality over doxorubicin-docetaxel and a clear advantage over both concurrent treatment approaches in terms of disease free survival,” Dr. Wolmark said.

In addition to Drs. Geyer and Wolmark, other AGH oncologists contributing to the study included D. Lawrence Wickerham, MD, AGH surgical oncologist and Associate Chair of the NSABP and Thomas Julian, MD, Associate Director of the AGH Breast Center and a Principal Investigator for the NSABP at AGH.

###

Read the full story at http://www.prweb.com/releases/Chemotherapy/Breast_Cancer/prweb4083994.htm.'/>"/>

Source: PRWeb
Copyright©2010 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Interruptions Make Doctors Lose Track of Tasks
2. Menstrual Cramps May Be Helped by New Drug
3. How to Say Goodbye to Premenstrual Syndrome (PMS) With the Click of a Button - A New Way to Avoid PMS
4. North Carolina Film Student Scores Big in Bicycle Safety Video Contest
5. Former Microsoft Employee Combines Passion For Technology With American Made Chris King Bicycle Parts
6. Motorcycle Cancer Risk and ELF EMF Radiation Invasion of Gastrointestinal Melatonin
7. Kramer Healthcare Technologies' RQi enterprise™ Revenue Cycle Solution Selected by Piedmont Healthcare
8. Motorcycle Fatalities Drop Sharply in U.S.
9. Tuba City Regional Health Care Corporation Selects Stockell Healthcare to Deploy Patient Access and Revenue Cycle Management Solution
10. Brain Cancer Survivor Will Cycle 4,170 Miles Across USA to Outsmart Disease
11. Greenway Medical Technologies Donates Electronic Health Record, Clinical Research and Revenue Cycle Solutions to Northern Kentucky University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... AZ (PRWEB) July 29, 2014 Nuanced ... they are now a HIPAA (Health Insurance Portability and ... standard for protecting the storage and transfer of Personal ... offered services compliant, Nuanced Media can effectively serve ... certification allows the agency to offer medical industry specific ...
(Date:7/29/2014)... July 29, 2014 Ticketability.com has reduced the ... already been selling at lower prices on the secure website. ... a further discount on tickets that are priced lower every ... of tickets available at Ticketability.com. , Theatergoers know that attending ... to find Phantom of the Opera tickets for sale that ...
(Date:7/29/2014)... All brides want their bridal dresses and bridal ... collection is sure to provide designs of wedding gowns ... stores. It has recently announced its new collection of ... new products come with big savings, up to 61% ... have been working in the garment industry for several ...
(Date:7/28/2014)... blood cell development have spread from Africa into nearly ... new study led by King,s College London. The international ... for the origin of changes in a key regulator ... haemoglobin is normally found in fetuses and infants, but ... to keep making it as adults experience milder symptoms ...
(Date:7/28/2014)... (PRWEB) July 29, 2014 NAPW ... at Kings County Hospital Center, as a 2014 Professional ... this prestigious distinction for leadership in community health. As ... country, spanning virtually every industry and profession, the National ... networking community with over 600,000 members and nearly 300 ...
Breaking Medicine News(10 mins):Health News:Nuanced Media Web Design Agency Now Hipaa Certified 2Health News:Phantom of the Opera Tickets for Sale: Ticketability.com Delights Customers with Phantom of the Opera Theatre Tickets While Seats Last 2Health News:LunaDress’ Summer Sale Has Arrived: All Its Gorgeous Lace Wedding Dresses are Affordable Now 2Health News:Study tracks worldwide spread of beneficial blood cell gene variant 2Health News:Study tracks worldwide spread of beneficial blood cell gene variant 3Health News:National Association of Professional Women Announces Pamela A. Schulters, Head Nurse at Kings County Hospital Center, a 2014 Professional Woman of the Year 2
... Pharmaceutical Services, Inc. (NYSE: WST ) today ... business assets of Plastef Investissements SA. Under the agreement ... safety syringe, a passive safety system for use with ... at Plastef,s production facility located in Le Vaudreuil, Normandy, ...
... DOR BioPharma, Inc. (OTC Bulletin Board: DORB) (DOR or ... it recently appointed Christopher P. Schnittker, CPA as its ... role, Mr. Schnittker will oversee the Accounting, Human Resources, ... Company,s Principal Accounting Officer for SEC reporting purposes. ...
... foods innovator, announced today that it is expanding its premium, all natural ... active consumers a unique, on-the-go snacking alternative that is both decadent and ... flavors--Chocolaty Cherry, Tropical and Fruit and Nut-- Bear Nake d (TM) ... Na tu ral Grain-ola ...
... finds wide variations in Web reports by states and municipalities ... local health departments in the United States get mixed marks ... about the swine flu outbreak, a new study shows. , ... April, 46 of 50 state health departments posted some information ...
... SAN DIEGO, July 7 US Farms, Inc. (Pink Sheets: USFM), ... it will be showcasing its business and products at the Natural ... 10-11, 2009 at the Venetian Resort Hotel. US Farms Booth number ... information, contact US Farms, Inc. Customer Service Department at 877-90-FARMS or ...
... DRRX ) today reported that King Pharmaceuticals, Inc. ... PTIE ) have announced that King met with ... to discuss the Complete Response Letter regarding the New Drug ... Pain Therapeutics, the outcome of the meeting last week provided ...
Cached Medicine News:Health News:West Acquires Drug Delivery Assets From Plastef Investissements SA 2Health News:DOR BioPharma Appoints Christopher P. Schnittker, CPA, as Vice President of Administration and Controller 2Health News:DOR BioPharma Appoints Christopher P. Schnittker, CPA, as Vice President of Administration and Controller 3Health News:DOR BioPharma Appoints Christopher P. Schnittker, CPA, as Vice President of Administration and Controller 4Health News:Bear Naked Introduces All Natural Granola Bars 2Health News:Mixed Marks for Swine Flu Updates 2Health News:US Farms, Inc. Showcasing Aloe Vera Product Line at Natural MarketPlace 2009 2Health News:REMOXY(R) NDA Update 2Health News:REMOXY(R) NDA Update 3Health News:REMOXY(R) NDA Update 4
(Date:7/29/2014)... July 29, 2014   ... that it has taken an exclusive worldwide licence to ... a Durham University spin-out company. ... pay an upfront fee, development and commercial milestone payments, ... also taken an option for additional exclusive licences to ...
(Date:7/28/2014)... 28, 2014 STAAR Surgical Company (NASDAQ: ... of implantable lenses and delivery systems for the eye ... and conference call with investors to July 31, 2014 ... Company rescheduled the release date and conference call to ... Hideo Watanabe , President of STAAR Japan, who ...
(Date:7/28/2014)... SOUTH SAN FRANCISCO, Calif. , July 28, 2014 ... ) today provided an update on the status of ... KB001-A collaboration with Sanofi Pasteur.  ... has reached an agreement with Sanofi Pasteur to regain ... the collaboration and licensing agreement entered into in 2010 ...
Breaking Medicine Technology:Glide Pharma Takes Exclusive Worldwide Rights to Novel Diagnostic Technology for Prostate Cancer 2Glide Pharma Takes Exclusive Worldwide Rights to Novel Diagnostic Technology for Prostate Cancer 3STAAR Surgical Moves Second Quarter Earnings Release and Conference Call One Day to July 31 2KaloBios Provides Update on KB001-A Partnership and Clinical Status 2KaloBios Provides Update on KB001-A Partnership and Clinical Status 3KaloBios Provides Update on KB001-A Partnership and Clinical Status 4KaloBios Provides Update on KB001-A Partnership and Clinical Status 5KaloBios Provides Update on KB001-A Partnership and Clinical Status 6
... national Tourette Syndrome Association, Inc., (TSA) has unveiled a ... to generate awareness and acceptance of all people living ... "We Have Tourette,s But Tourette,s Doesn,t Have Us" ... struggle everyday with the symptoms of involuntary sounds and ...
... NEW YORK, July 4, 2011 ... research report is available in its ... - Global Pipeline Analysis, Competitive Landscape ... http://www.reportlinker.com/p0567378/Gastrointestinal-Endoscopes---Global-Pipeline-Analysis-Competitive-Landscape-and-Market-Forecasts-to-2017.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Imaging ...
Cached Medicine Technology:EHE International Showcases The National Tourette Syndrome Association, Inc. with Month-Long Window Display in Rockefeller Center Plaza 2Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 2Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 3Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 4Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 5Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 6Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 7Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 8Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 9Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 10Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 11Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 12Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 13Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 14Gastrointestinal Endoscopes - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 15
Red Rubber Robinson Catheters (Latex)...
Silver Foley Catheter 3-way...
Silicone-Coated Foley Catheter 2-Way...
Silicone Foley Catheters 2-Way (Pediatric)...
Medicine Products: