Navigation Links
Internet searches can identify drug safety issues well ahead of public alerts
Date:3/6/2013

The authors base their findings on an analysis of the anonymised search logs of millions of US web users, who agreed to install a browser add-on and share their online searches with Microsoft throughout 2010.

The researchers developed automated tools to analyse the queries of people who searched for information on the antidepressant (paroxetine) and a cholesterol lowering drug (pravastatin), using the search engines Google, Bing and Yahoo.

In 2010, it was not yet public knowledge that taking both these two drugs caused high blood sugar (hyperglycaemia), but the authors later extracted this information by mining the US drugs regulator's medicines side effect reporting system (AERS) and confirming the finding in a separate laboratory study.

In the web log study, the authors looked at whether people who had searched online for either one of the drugs separately, or for both of them, would also search with queries containing terms associated with the symptoms of high blood sugar.

In all, they analysed 82 million drug, symptom, and condition queries from among 6 million web users.

They found that online searches for information on prescription drugs was common, with more than one in 250 people looking up at least one of the 100 top selling drugs in the US, including paroxetine and pravastatin.

For people who searched online for both drugs during the 12 month period, queries were made on the same day in almost a third (29.61%) of searches, while four out of 10 were in the same week. Six out of 10 were made within the same month.

During the study period, those people who looked up both drugs online were almost twice as likely to search for terms associated with high blood sugar as were those who looked up the drugs separately.

One in 10 of those looking up both drugs did this, compared with around one in 20 of those looking up each drug separately. Just 0.3% of all users searched for one or more terms associated with high blood sugar over the 12 months.

These differences in search patterns were evident across the whole period of the study, and were not influenced by public information as the discovery of the interaction between this particular pair of drugs was only made in 2011.

Analysis of other 31 drug pair interactions associated with high blood sugar also indicated similar patterns, suggesting that the value of log analysis is not just confined to paroxetine and pravastatin.

"There is a potential public health benefit in listening to such signals, and integrating them with other sources of information," write the authors. "We see a potentially valuable signal, even though search logs are unstructured, not necessarily related to health, and can include any words entered by users," they add.

And they conclude: "We believe that patient search behaviour directly captures aspects of patients' concerns about sensed [symptoms] and can complement more traditional sources of data for pharmacovigilance [drug safety monitoring]."


'/>"/>

Contact: Emma Dickinson
edickinson@bmjgroup.com
44-020-738-36529
BMJ-British Medical Journal
Source:Eurekalert

Related medicine news :

1. End to End Networks Launches New Connectivity Services - Dedicated MPLS Private and Internet Solutions
2. PRMA Pink Ladies Gaining Members Across the Country Through Monthly Live Internet Meetings, Offering Support and Inspiration to Breast Cancer Survivors
3. Worldwide Internet Sensation and Ashland Musician George Dennehy Performs at the Science Museum of Virginia
4. Mega Travel Club Travel Services (also known as mytsonline) Implements New Program to Help Members Avoid the Internet Scams and Ripoffs
5. Internet use can reduce fatalistic view of cancer
6. Attorney Deborah Truhowsky Featured On “Paying It Forward” Internet Broadcast Program
7. Internet Speaker, Founder, and President of RevenFlo Web Team, Jason Broadwater, Discusses the Most Essential Marketing Tool Available for Effective Internet Marketing
8. The Internet becomes next Nostradamus for allergy season
9. Could Internet Addiction Be Genetic?
10. Internet addiction -- Causes at the molecular level
11. Sites, LLC Announces the Celebration of Green Van Dyck: Director of Sales and Internet Marketing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2016)... ... December 11, 2016 , ... A brand new organic ... has introduced 16 new products to it's existing line. "We started with a ... wanted to supply more products to our customers that would provide safe and ...
(Date:12/10/2016)... ... December 10, 2016 , ... ... PATS recently joined forces with other healthcare organizations to promote diabetes education ... Rotunda in Harrisburg, featured a variety of speakers from around the Commonwealth of ...
(Date:12/9/2016)... ... December 09, 2016 , ... Cellairis is a worldwide mobile device and ... iPhone , iPad and Samsung Galaxy devices with premium parts and accessories. ... to maximize convenience and accessibility for customers. While customers do their shopping, Cellairis can ...
(Date:12/9/2016)... (PRWEB) , ... December 09, 2016 , ... An inventor ... amputees to safely ride all types of amusement park rides. , The patent-pending SAFETY ... unit is easy to use and could be set up in a matter of ...
(Date:12/9/2016)... , ... December 09, 2016 , ... ... through the Pennsylvania Cable Network (PCN) during the summer of 2016. The program ... Grant provided by the United States Department of Health and Human Services Administration. ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... Texas , Dec. 9, 2016  RxWiki Inc., ... apps, and digital marketing strategies of thousands of pharmacies ... it won Austin Inno,s "50 on Fire" ... "We,re pleased to accept the award as ... Loughlin , Chief Executive Officer at RxWiki. "Our platform ...
(Date:12/9/2016)... , Dec. 9, 2016  Forge Therapeutics, ... AG (Frankfurt Stock Exchange: EVT, TecDAX, ISIN: DE0005664809) ... ,LpxC, for the treatment of bacterial infections including ... been recognized as an attractive antibacterial target for ... lack of suitable chemical starting points has hampered ...
(Date:12/8/2016)... , Dec. 8, 2016 KEY FINDINGS ... Patient ... loss of blood during surgeries, lowering the risks of neurological ... risks of SSIs. The patient warming systems can be segmented ... systems.These benefits in turn reduce the stay at hospitals thus, ...
Breaking Medicine Technology: