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International study finds heart disease similar in men and women
Date:12/2/2013

CHICAGO An analysis of data from an international multicenter study of coronary computed tomography angiography (CCTA) reveals that men and women with mild coronary artery disease and similar cardiovascular risk profiles share similar prognoses. Results of the study were presented today at the annual meeting of the Radiological Society of North America (RSNA).

"We conducted this study because we wanted to understand whether men and women with the same extent of coronary artery disease and similar risk profiles have similar or dissimilar prognoses," said Jonathon Leipsic, M.D., FRCPC, director of medical imaging at St. Paul's Hospital in Vancouver, British Columbia. "There is a tendency to think women's heart disease is very different than men's heart disease. Our data show that once plaque accumulates in the coronary arteries, the prognosis is very similar between men and women."

Coronary artery disease occurs when the coronary arteriesthe major blood vessels that supply the oxygen-rich blood to the heart musclebegin to accumulate a buildup of fatty deposits called plaque. Over time, plaque may damage or narrow the arteries. CCTA is a noninvasive imaging test that uses computed tomography (CT) to image the amount of plaque present in the coronary arteries.

For the study, Dr. Leipsic and a team of researchers used data from the COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter (CONFIRM) Registry, which collected information on 27,725 individuals in six countries who underwent CCTA. The registry also included participants' traditional risk factors, allowing for the derivation of Framingham scores, which are used to determine an individual's risk of developing cardiovascular disease.

From the registry, the researchers identified 18,158 patients without known coronary artery disease, whose CCTA results were normal or indicated nonobstructive disease, in which coronary arteries were less tha
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Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

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