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International study confirms doubling of childhood leukemia rates in southern Iraq
Date:2/18/2010

Seattle, Feb. 18 -- Childhood leukemia rates have more than doubled over the last 15 years in the southern Iraq province of Basrah, according to the study, "Trends in Childhood Leukaemia in Basrah, Iraq (1993-2007), published in the American Journal of Public Health.

The authors, three of whom are from the University of Washington, say they hope their calculations can now pave the way for an investigation into reasons why the rates have climbed so high, and why they are higher than found in nearby Kuwait, or in the European Union or the United States.

The study documents 698 cases of leukemia for children aged 0-14 during the 15-year period, with a peak of 211 cases in 2006. Younger children had higher rates than older ones.

"By using a hospital cancer registry, we were able to measure a jump in leukemia rates from 3 per 100,000 youngsters in the first part of our study period, to a rate of almost 8 and a half in the final three years," said UW Department of Global Health faculty member Amy Hagopian, the paper's lead author.

By comparison, Hagopian said, the European Union and the United States report rates of 4 and 5 per 100,000, respectively. She also noted Kuwait reports a rate of approximately 2 per 100,000 and Oman reports rates between 2 and 3, depending on the gender of the child (boys typically have higher rates, as do children from higher socio-economic classes).

"Studying childhood diseases in war situations is difficult," Hagopian noted. "Aside from the normal difficulties of controlling for referral patterns changes caused by war-time conditions, the political situation is also challenging. We were constantly worried about the political risks our medical colleagues were taking by collecting and reporting these data."

Another author of the paper, UW Department of Epidemiology Chairman Scott Davis, noted, "Another challenge was securing population data for purposes of calculating rate
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Contact: Bobbi Nodell
bnodell@u.washington.edu
206-271-1429
University of Washington - Health Sciences/UW News, Community Relations & Marketing
Source:Eurekalert

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