Navigation Links
International space station plays host to innovative infectious disease research
Date:2/19/2013

d with infection and disease not possible using traditional experimental conditions on Earth, where the force of gravity can mask certain cellular responses. Further, experiments aboard the ISS will permit the study of microbial transitions and cellular responses to infection over a prolonged time frame - an important advance not available during shuttle-based experiments.

Microgravity research may provide an opportunity to identify novel targets for vaccine development and the Nickerson team, in collaboration with Roy Curtiss, director of the Biodesign Institute's Center for Infectious Diseases and Vaccinology has been working toward this goal. Based on previous findings, the scientists hypothesized that results from microgravity experiments might be used to facilitate vaccine development on Earth.

In a recent spaceflight experiment aboard space shuttle mission STS-135, the team flew a genetically modified Salmonella-based anti-pneumoccal vaccine that was developed in the Curtiss lab. By understanding the effect of microgravity culture on the gene expression and immunogenicity of the vaccine strain, their goal is to genetically modify the strain back on Earth to enhance its ability to confer a protective immune response against pneumococcal pneumonia.

"Recognizing that the spaceflight environment imparts a unique signal capable of modifying Salmonella virulence, we will use this same principle in an effort to enhance the protective immune response of the recombinant attenuated Salmonella vaccine strain," Nickerson says.

Nickerson's space-based microgravity experiments are carried out in conjunction with simultaneous Earth-based controls housed in the same hardware as those in orbit, to compare the behavior of bacterial cells under normal Earth gravity. Additional information is also provided using Earth-based cell cultures which are subjected to a kind of simulated microgravity, produced by culturing cells
'/>"/>

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4 5 6

Related medicine news :

1. International breast health global summit will focus on supportive care and quality of life
2. International conference to explore health of descendants of transatlantic slave trade
3. Kessler Foundation researchers present at first International Congress on Cognition in MS
4. Internationally known expert in ovarian cancer to be honored at the ASCO Annual Meeting
5. Nobel laureate to keynote international pharmaceutical conference at URI
6. International Nanomedicine Conference bound for Sydney: July 2-4, 2012
7. June 2012 marks a milestone for International Urogynecology Associates as Dr. Robert D. Moore and Dr. John R. Miklos perform their 24th Neovagina Surgery in 24 months
8. Heavy Duty Alternators and Starters Expert Elreg Distributors Ltd. Meets Needs of International Market with Launch of Spanish Website
9. The US Drug Watchdog Now Urges Plaintiffs Law Firms Worldwide To Contact Them About A Possible International Effort To Help Victims Of Defective Drugs Or Medical Devices
10. RMAX International to donate Recuper8 - a free, health - restoring program to Everyone in Uniform
11. International symposium on veterinary rehabilitation and physical therapy to be held in Vienna
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
International space station plays host to innovative infectious disease research
(Date:3/4/2015)... When people talk about venues being the place to be ... the Houston Rodeo will be a name that ... livestock show and rodeo, one popular band will perform for ... at the event. The 2015 show will feature one of ... get the festival its largest attendance ever. , Houston Rodeo ...
(Date:3/4/2015)... WV (PRWEB) March 04, 2015 TROY ... (TSPE) software, which provides the ultimate level of security ... at the Hilton Houston Plaza Medical Center located at ... , Beginning at 7 AM, TROY Healthcare Solutions ... TROY Healthcare Solutions will offer brief presentations each hour ...
(Date:3/4/2015)... March 04, 2015 The ability ... in density assessment and help improve breast cancer ... abstracts accepted for presentation at the European Congress ... Ten abstracts - eight posters and 2 session ... automated breast density and quantitative breast imaging software ...
(Date:3/4/2015)... Blake’s All Natural Foods , ... attend this year’s Natural Products Expo West in Anaheim, ... this new line, Blake’s, who has the top four ... its commitment to creating high-quality dishes that are easily ... the natural channel, Blake’s understands what educated consumers are ...
(Date:3/4/2015)... (PRWEB) March 04, 2015 Vancouver ... recently received two awards in the prestigious Vancouver ... on February 27, 2015. The company secured third ... place in the “Best Registered Massage Therapist” category. ... community newspapers in Canada, The Vancouver Courier is ...
Breaking Medicine News(10 mins):Health News:Cheap Houston Rodeo Tickets: Ticket Down Slashes Houston Rodeo Tickets for John Legend, Pitbull, Alan Jackson, Tim McGraw, Zac Brown Band, Fall Out Boy & Miranda Lambert 2Health News:Cheap Houston Rodeo Tickets: Ticket Down Slashes Houston Rodeo Tickets for John Legend, Pitbull, Alan Jackson, Tim McGraw, Zac Brown Band, Fall Out Boy & Miranda Lambert 3Health News:TROY Healthcare to Offer Prescription Solutions that can save a Hospital $100,000 2Health News:TROY Healthcare to Offer Prescription Solutions that can save a Hospital $100,000 3Health News:Research Finds Use of Volpara Solutions’ Quantitative Breast Imaging Tools Help Reduce Subjectivity in Density Assessment and Improve Breast Cancer Risk Prediction 2Health News:Research Finds Use of Volpara Solutions’ Quantitative Breast Imaging Tools Help Reduce Subjectivity in Density Assessment and Improve Breast Cancer Risk Prediction 3Health News:Research Finds Use of Volpara Solutions’ Quantitative Breast Imaging Tools Help Reduce Subjectivity in Density Assessment and Improve Breast Cancer Risk Prediction 4Health News:Research Finds Use of Volpara Solutions’ Quantitative Breast Imaging Tools Help Reduce Subjectivity in Density Assessment and Improve Breast Cancer Risk Prediction 5Health News:Fastest Growing Frozen Brand in Natural Channel Showcases New Line at Expo West 2015 2Health News:Fastest Growing Frozen Brand in Natural Channel Showcases New Line at Expo West 2015 3Health News:Backs in Action Receives Two Awards in The Vancouver Courier Readers’ Choice Awards 2015 2
... Institute for Tuberculosis and HIV (K-RITH) has awarded a ... South African scientists and students to help build new ... These are the first Collaborative Grants awarded by K-RITH, ... the University of KwaZulu-Natal (UKZN) and the Howard Hughes ...
... nuclear incident, researchers at Thomas Jefferson University ... an award to find novel drugs to treat people ... of a nuclear terrorist attack or a nuclear accident. ... given to six institutions under the National Institute ...
... 2011 The Translational Genomics Research Institute (TGen) has ... cancer tumors by modifying the actions of proteins. ... mission: To move laboratory discoveries more rapidly into therapeutics ... life. The drug, ONCO-101, is being licensed to ...
... May 4 (HealthDay News) -- Adults often find it hard ... about their wishes and hopes revealed some interesting trends, researchers ... 18, who completed a health screening questionnaire that included the ... be?" The researchers found that 85 percent of participants ...
... and the Management Sciences (INFORMS) will host its first ... 2011 takes place at the Hilton Bonaventure Hotel in ... range from improving the scheduling of patients at clinics ... for beaming radiation at cancer cells. , The conference ...
... News) -- Being sociable can help keep your brain healthy ... University Medical Center found that elderly people with the highest ... friends, going to parties or attending church -- showed much ... least socially active. The study included 1,138 ...
Cached Medicine News:Health News:K-RITH awards grants to foster teamwork among South African TB/HIV scientists 2Health News:Thomas Jefferson University and hospitals tasked to find new radiation drugs 2Health News:TGen licenses first drug for patient use in clinical care 2Health News:Simple Question Sheds Light on Teens' Hopes, Dreams 2Health News:Socializing May Keep Elderly Minds Sharp 2
(Date:3/4/2015)... March 4, 2015  Nevro Corp. (NYSE: ... and commercialized an innovative, evidence-based neuromodulation platform for the ... release financial results for the fourth quarter  and full ... 18, 2015. Company management will host a conference call ... Time) on Wednesday, March 18, 2015. ...
(Date:3/4/2015)... -- Mail-service and specialty pharmacies will save ... plans $11.8 billion over the next decade, according ... Association (PCMA). "Home delivery of traditional ... ways to reduce health costs," said PCMA President ... resist efforts to restrict these cost-saving tools." ...
(Date:3/4/2015)... , March 4, 2015 From ... attending the 2015 Distribution Management Conference and Expo ... conference is HDMA,s largest supply chain education event, ... third parties who keep the pharmaceutical distribution industry ... on regulatory and legislative issues important to healthcare ...
Breaking Medicine Technology:PCMA: Report Shows High-Tech Specialty and Mail-Service Pharmacies Will Reduce Costs for Illinois Employers, Consumers and Public Programs by $11.8 Billion 2
... Pharmaxis (ASX: PXS; Nasdaq: PXSL) today announced,that the ... safety of,Bronchitol in subjects with bronchiectasis has concluded ... following 12 months of treatment., A total ... Bronchitol twice,per day and 99 subjects completed the ...
... 19 Particle Sciences Inc. has,expanded its ... capabilities with the installation of a compounding,extrusion ... the pilot line,comprising a Haake twin-screw compounding ... production of high-quality drug loaded polymeric,devices. This ...
Cached Medicine Technology:12 Month Phase 3 Trial Finds Bronchitol Safe in Bronchiectasis 212 Month Phase 3 Trial Finds Bronchitol Safe in Bronchiectasis 3Particle Sciences Expands Its Combination Product Capabilities 2
... is intended for the quantitative determination of Erythropoietin ... for in vitro diagnostic use, as an aid ... the advent of the administration of recombinant erythropoietin ... cell mass, an erythropoietin assay may be used ...
Fully automated immunochemiluminometric assay for the rapid intraoperative,measurement of Intact PTH 1-84 using human serum or EDTA plasma....
Microwell EIA for the detection of EPO (Erythropoietin)...
Microwell IRMA for the detection of Intact PTH...
Medicine Products: