Navigation Links
International Travel Raises Risk of Typhoid
Date:8/25/2009

Drug-resistant strains most common among visitors to Indian subcontinent, CDC reports

TUESDAY, Aug. 25 (HealthDay News) -- International travel is the most common cause of infection with an antimicrobial-resistant strain of typhoid fever among patients in the United States, a new study finds.

About 300 cases of typhoid fever are reported in the United States each year, and the majority of these cases are associated with foreign travel, especially to India, Pakistan and Bangladesh. Over the last 20 years, the emergence of Salmonella serotype Typhi strains resistant to antimicrobial drugs has complicated the treatment of patients in the United States, according to researchers at the U.S. Centers for Disease Control and Prevention.

The CDC team studied data on 1,902 people, median age 22, treated for typhoid fever in the United States between 1999 and 2006, and examined the test results of 2,016 Salmonella Typhi samples submitted to the CDC for analysis.

The researchers found that 1,295 (73 percent) of the patients were hospitalized and three (0.2 percent) died. They also found that 1,439 (79 percent) of the patients had traveled overseas within 30 days before they became ill, and only 58 of the travelers (5 percent) had received typhoid vaccine.

Three countries accounted for more than two-thirds of all travel-associated cases of typhoid fever -- India (47 percent), Pakistan (10 percent) and Bangladesh (10 percent).

The study appears in the Aug. 26 issue of the Journal of the American Medical Association.

The researchers also found that "272 [13 percent] of 2,016 isolates tested were resistant to ampicillin, chloramphenicol and trimethoprim-sulfamethoxazole [multidrug-resistant S. Typhi]; 758 [38 percent] were resistant to nalidixic acid [nalidixic acid-resistant S. Typhi [NARST]], and 734 NARST isolates [97 percent] had decreased susceptibility to ciprofloxacin. The proportion of NARST increased from 19 percent in 1999 to 54 percent in 2006," Dr. Michael F. Lynch, of the CDC, and colleagues wrote in a news release from the journal.

Resistant infections were most likely to occur in patients who had traveled to the Indian subcontinent. These patients accounted for 85 percent of multidrug-resistant S. Typhi infections, 94 percent of nalidixic acid-resistant infections and 44 percent of susceptible infections, the researchers noted.

"Since most typhoid fever among patients treated in the United States is acquired abroad, ongoing surveillance may also help track global patterns of antimicrobial resistance of S. Typhi. Reducing the burden of typhoid fever in the United States will require increased attention to prevention measures by travelers, including improved vaccination coverage among travelers to typhoid-endemic areas," the authors concluded. "Further reductions in typhoid fever among travelers will depend on increased availability of safe drinking water as well as improved sanitation and food hygiene in typhoid endemic areas, measures that would go a long way toward reducing the global burden of typhoid fever."

More information

The CDC has more about typhoid fever.



-- Robert Preidt



SOURCE: Journal of the American Medical Association, news release, Aug. 25, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. TBI/Tissue Banks International and Northwest Tissue Services Announce Collaborative Distribution Agreement
2. HBA Global Announces Finalists for the 2009 International Package Design Awards (IPDA)
3. Jani-King Recognized as Best in Support by the International Business Awards
4. The Donor Source International, LLC Opens Office in New England
5. International Micro Industries (IMI) is ITAR Registered
6. Dallas Physician Elected to Lead International Organ Transplant Society
7. HeartWare International Surpasses 50 Implants in the US
8. Former GE Executive Joins Lifeclinic International
9. Chindex International, Inc. Announces New CDC Contract
10. Profiles International Releases New Study Identifying Key Factors for Strategic Workforce Planning
11. Reliv International Launches New Products and Business Tools at 21st International Conference
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
International Travel Raises Risk of Typhoid  
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/26/2016)... Orion, Clarkston, Michigan (PRWEB) , ... June 26, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse but they also require a comprehensive approach that can help for preservation ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
(Date:6/25/2016)... Aliso Viejo, California (PRWEB) , ... June 25, 2016 , ... ... preset to fit their specific project," said Christina Austin - CEO of Pixel Film ... all fully customizable and all within Final Cut Pro X . Simply select ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, ... and his M.D from the David Geffen School of Medicine at UCLA. He trained ... Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Research and Markets has ... - Forecast to 2022" report to their offering. ... for the patients with kidney failure, it replaces the function ... the patient,s blood and thus the treatment helps to keep ... in balance. Increasing number of ESRD patients ...
(Date:6/23/2016)... , June 23, 2016 Research and ... Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data derived ... Assessment of major trends with potential impact on the market ... of market segmentation which comprises of sub markets, regional and ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
Breaking Medicine Technology: