Navigation Links
Internal bleeding higher with popular heart device than earlier model
Date:6/11/2011

DETROIT The incidence of internal bleeding was higher in the most commonly implanted heart device than in an earlier model, according to two studies at Henry Ford Hospital in Detroit.

The HeartMate II, a left ventricular assist device (LVAD) is a continuous-flow mechanical pump connected to the patient's heart that takes over the pumping of the weakened heart's left ventricle.

"Although there were more instances of bleeding in the skull and gastrointestinal track with the HeartMate II, as opposed to the earlier model, there was no increase in mortality," says lead author Jeffrey A. Morgan, M.D., associate director of Mechanical Circulatory Support in the Edith and Benson Ford Heart &Vascular Institute at Henry Ford.

Dr. Morgan will present the studies on June 11 at the annual conference of the American Society of Artificial Internal Organs in Washington, D.C.

From March 2006 through May 2010, 64 patients with chronic heart failure underwent implantation of a HeartMate II LVAD as a bridge to transplant or a permanent therapy for those ineligible for transplants.

The incidence of gastrointestinal bleeding or adverse neurological events (ANE) was evaluated to determine their impact on survival and identify predictors of occurrence.

The overall incidence of gastrointestinal bleeding was nearly 22 percent, and the incidence of major ANEs was eight percent. Patients with an ANE were significantly older, with a higher incidence of chronic renal insufficiency. They also had higher International Normalized Ratios (INRs), a lab test that measures the time it takes for blood to clot, and compares it to an average, at the time of the event. The higher the INR, the longer it takes blood to clot.

No complications due to blood clots occurred in those with gastrointestinal bleeding, but for patients with an ANE, there were four intracranial hemorrhages and one thromboembolic stroke.

There was no significant difference in gender, race, cause of heart failure, diabetes, or body mass index (BMI) between patients who had post-operative bleeding and those who did not.

Study co-author Robert J. Brewer, M.D., surgical director of the Mechanical Circulatory Support Program at Henry Ford, believes that as data accumulates on the relatively low incidence of thromboembolic events with the HeartMate II for patients on low-dose or no anticoagulation, it may be prudent to lower the goal INR, with the intent of lowering bleeding complications.

The HeartMate II is smaller, with fewer moving parts, than the previous model, the HeartMate I XVE, and requires less invasive surgery. Its size makes it available to a larger number of advanced-stage heart failure patients, and it has been predicted to greatly increase patients' quality of life. The device can cover the full output of a healthy heart. Studies have shown that continuous-flow pumps last much longer than pulsing pumps before they must be replaced.

Usage of LVADs has increased in the United States, where heart failure affects five million people, but there are less than 3,000 donor organs available annually worldwide. Last year, nearly 2500 patients were implanted with the device in the United States, which is used chiefly for those waiting for a heart transplant due to the chronic donor shortage. In other cases, it is used for long-term support in patients who are not candidates for a heart transplant.


'/>"/>

Contact: Sally Ann Brown
sbrown2@hfhs.org
313-874-6280
Henry Ford Health System
Source:Eurekalert

Related medicine news :

1. Embargoed News from Annals of Internal Medicine
2. Convert2XHTML.com Now Introduces Separate Team for Quality Check and Internal Audit to Improve Quality PSD to HTML Conversion
3. Internal Anthem Blue Cross/WellPoint Document: Only Patients Who Push Back Get Covered Out of State Liver Transplants
4. Keynote Speaker Presents Top Business Plan For Internal Communication Through Social Media
5. All you need to know about adult medicine is at Internal Medicine 2010
6. TPG Capital Selects MetricStream GRC Platform to Boost its Internal Controls and Compliance
7. IMNG relaunches Internal Medicine News Digital Network and Hospitalist News Digital Network
8. Story opportunities for journalists at ACPs Internal Medicine 2011
9. Embargoed news from Annals of Internal Medicine
10. Genetic cause discovered for rare bleeding disorder
11. Bleeding Alert Sounded for Stroke Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... March 23, 2017 , ... ... publication of “Profiling protein expression in circulating tumor cells using microfluidic western blotting” ... use of the Vortex technology to capture CTCs and a microfluidic ...
(Date:3/22/2017)... ... March 22, 2017 , ... ... Milpitas with a robust, ongoing community enrichment program, has announced their latest charity ... which has provided for the critical needs of homeless families with children for ...
(Date:3/22/2017)... ... March 22, 2017 , ... In recognition of Colon ... enterprise focused on cancer patients, cancer centers and advocacy groups, and MJH Studios™, ... video series, “No Ifs, Ands, or Butts,” that focuses on Colorectal Cancer detection, ...
(Date:3/22/2017)... ... March 22, 2017 , ... Drs. Jennifer Houck, Lauren ... base to accept new patients in need of skilled pediatric dentistry in ... Dental Care offers pediatric patients routine treatments, including cavities, sealants and fluoride applications, in ...
(Date:3/22/2017)... ... March 22, 2017 , ... The Carballo Agency, ... and the New York metropolitan region, is embarking on a cooperative charity drive ... , At present, more than two and a half million children in the ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... ROCHESTER, N.Y. , March 22, 2017 /PRNewswire/ ... Steriliz R-D™ Rapid Disinfector™ is the proven ultraviolet-C ... that cause healthcare-associated infections (HAIs). ... American Journal of Infection Control , the peer-reviewed ... testing and experiences of Vancouver General Hospital and ...
(Date:3/22/2017)... 22, 2017 FinancialBuzz.com News Commentary ... rapidly due to the significant development and innovation in ... Market Research, the global electrophysiology market was worth $3.42 ... billion by 2022, with a GAGR of 13.4%. Electrophysiology ... diagnose abnormal heartbeats or arrhythmia. The report indicates that ...
(Date:3/22/2017)... , March 22, 2017 Kalorama Information has ... important to those following the industry.  This month the FDA ... test, and the POC testing market has reached $18.4 ... subsidiary is facing a legal battle and the acquisition ... Coulter launched a new chemistry analyzer and researchers ...
Breaking Medicine Technology: