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Interleukin Genetics to Present Data Highlighting Link Between Inflammatory Gene Variations and Less Effective Weightloss
Date:1/22/2009

Findings to be Presented at This Week's Keystone Symposium - Obesity: Novel Aspects of the Regulation of Body Weight

WALTHAM, Mass., Jan. 22 /PRNewswire-FirstCall/ -- Interleukin Genetics, Inc. (NYSE Alternext US: ILI) announced today that the company will present new research findings on the role genetics play in an individual's ability to lose weight and body fat while following a calorie-restricted diet, during tomorrow's Keystone Symposium titled, "Obesity: Novel Aspects of the Regulation of Body Weight." The Symposium, held January 20-25, 2009, is taking place at the Fairmont Banff Springs, Banff, Alberta, Canada.

Interleukin Genetics will present the study findings during poster session #3 taking place tomorrow, January 23, between 7:30 - 10:00 p.m. The poster, titled "Association of genes involved in chronic inflammation with weight management in response to the carbohydrate content of diet under calorie restriction," highlights new findings on the influence of genetic polymorphisms in the genes of interleukin-1 (IL-1) inflammatory pathway on dietary intervention induced weight and body fat loss.

"In this study, we investigated whether inflammatory gene variations were associated with response to weight-loss in overweight subjects," said Nazneen Aziz, Vice President of Research and Development at Interleukin Genetics. "We found that individuals with a specific genetic make-up were resistant to loss of body weight and body fat when they were placed on a calorie restriction diet, but individuals with the same genetic pattern were more likely to lose weight if their diet was not only calorie-restricted but also had a low glycemic content."

These results suggest that inflammatory gene variations could have important clinical utility in the design of optimal weight-loss programs in the overweight population.

The findings are the result of a study performed in collabora
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SOURCE Interleukin Genetics, Inc.
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