Navigation Links
Interesting stories at the IMPAKT Breast Cancer Conference
Date:5/7/2010

breast cancer? The sodium-iodide symporter
N. Fortunati, ITALY,
The sodium-iodide symporter (NIS) mediates iodide uptake into thyroid cells allowing radioiodine imaging and therapy in thyroid cancer. NIS is also expressed in lactating mammary glands, and in more than 80% of human breast carcinomas. This study reports that the pan-deacetylase (DAC) inhibitor LBH589 induces NIS expression and function in breast cancer cultured cells. LBH589 appears to be an interesting compound in the managing of breast cancer, giving the opportunity of using radioiodide as further diagnostic and therapeutic tool.

Abstract 143P: Combination of ASA404 (vadimezan) with paclitaxel and trastuzumab
D.B. Evans, SWITZERLAND
ASA404 is a flavonoid, non tubulin-binding Tumour-Vascular Disrupting Agent that induces breakdown of the established tumor vasculature and hence inhibition of the tumor blood supply, leading to ischemia and extensive necrosis of the tumor core. This study shows that it enhances the activity of trastuzumab and paclitaxel, highlighting the potential value of this combination in breast cancer treatment.

Abstract 105P: Overcoming trastuzumab resistance?
M. Gijsen, UNITED KINGDOM.
It is still poorly understood how trastuzumab exerts its tumor inhibition effect. Its acquired resistance mechanisms are also not yet fully determined. This study provides evidence that trastuzumab resistance can be mediated by activation of HER family ligands as a result of a PKB negative feedback loop. This offers treatment opportunities for overcoming resistance in these patients, including approaches to target all HER receptors in combination with trastuzumab treatment.


'/>"/>

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. And the Winner is… After Online Vote, Austin Cosmetic Dentist Crowns the Most Interesting Dental Patient in the World
2. 10 Days Left to Win $15,000 in Dental Work for Most Interesting Patient in the World Contest at Austin Cosmetic Dentistry Practice
3. The Top Health Stories Of 2009, From The Harvard Health Letter
4. Phonak Asks Young FM Users to Tell Their Stories on YouTube
5. National Kidney Month 2010: Stories of Hope About the Prevention and Maintenance of Kidney Disease from The Kidney TRUST
6. Upstate Business Tells Stories Through New Media
7. IMPAKT Breast Cancer Conference press program
8. Targeted therapy prolongs life in patients with HER2-positive breast cancer
9. New Drugs, New Combinations Fight Breast Cancer
10. Study Finds Possible Explanation for the Link Between Infertility and Breast/Ovarian Cancer Risks
11. Carol Milgard Breast Center Awarded Highest Government Rating for Mammography Sites
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... (PRWEB) April 18, 2015 Review of ... hosting a ‘Strategies for Success’ program for cataract surgeons ... meeting in San Diego, where eye surgeon Jeffrey L. ... this invitation-only event. Dr. Martin is the Managing Partner ... of Ophthalmology chose Dr. Martin to lead this year’s ...
(Date:4/18/2015)... (PRWEB) April 18, 2015 Thousand of ... on behalf of individuals who were allegedly harmed by ... to move forward in the U.S. District Court, Northern ... 10th, the Court has amended an earlier Case Management ... Among other things, the new amendment permits the claims ...
(Date:4/18/2015)... (PRWEB) April 18, 2015 “ ArcAngel ” ... which takes a look at the latest and coolest ... Joe Troohey, the host of AppWatch and technology expert, conducted ... a personal safety app. , In a turbulent world, ... help. Calling 911 should always be their first move, but ...
(Date:4/17/2015)... 2015 Rosetta Radiology is proud to ... their list of diagnostic imaging services. This solidifies them ... the Upper East Side of Manhattan. , The new ... The addition of PET-CT, combined with Rosetta’s state of ... to work with patients through several stages of the ...
(Date:4/17/2015)... “We have seen healing, a lot of healing, and ... Chaplain Shawn Kafader of Friendship Village. “People have found ... to contribute have created beautiful pieces of art.” For the ... program that was launched to benefit residents of the retirement ... the Art Institute in Chicago, worked as an intern at ...
Breaking Medicine News(10 mins):Health News:Dr. Jeffrey Martin Invited to Share Latest Breakthroughs in Cataract Care During Roundtable Discussion at National 2015 ASCRS Meeting In San Diego 2Health News:DePuy Pinnacle Hip Lawsuits: Federal Litigation Amends Case Management Order to Allow for Joinder of Unrelated Claims 2Health News:DePuy Pinnacle Hip Lawsuits: Federal Litigation Amends Case Management Order to Allow for Joinder of Unrelated Claims 3Health News:A Personal Safety Application was Featured on NewsWatch Television 2Health News:Healing At Friendship Village Due To Art Therapy 2
... impairment appears to be more common in people with ... a report in the October issue of Archives ... journals. , Approximately 14.6 million Americans had diagnosed ... undiagnosed diabetes, according to background information in the article. ...
... deprived of body,s sleep-wake system ,can,t remember anything, study ... body clock may do more than help guide your ... vital role in learning and memory, say Stanford University ... a functioning circadian system is critical to the rodents, ...
... Earnings Conference Call on October 30 - - Presentation at Oppenheimer,s 19th Annual Healthcare ... ... ... 7 -, SAN DIEGO, Oct. 13 Gen-Probe Incorporated,(Nasdaq: GPRO ) announced today ...
... Oshkosh is one of six sites included in national ... because of low cardiac arrest survival rates, OSHKOSH, ... ) announced today that it has,received an additional $1.5 ... to continue a study testing two devices used in ...
... Content Rights Management System, Supports Global Pharma ... Spend, WEST CHESTER, Pa., Oct. 13 ... manufacturer has integrated,Modevity,s Imperium technology to become the ... tracking and reporting,analytics for their new product video ...
... Away, FORT WORTH, Texas, Oct. 13 The ... at the Will Rogers Memorial,Center. The company, which has ... bottles of free Dannon smoothies and demonstrated support,for a ... FitFuture KIDS Fest is to help educate families about ...
Cached Medicine News:Health News:Vision loss more common in people with diabetes 2Health News:Circadian Rhythm Plays Role in Memory 2Health News:Gen-Probe Announces Webcasts of Three Upcoming Investor Events 2Health News:Gen-Probe Announces Webcasts of Three Upcoming Investor Events 3Health News:Advanced Circulatory Systems Receives $1.5 Million From NIH for Study of Cardiac Arrest Resuscitation Techniques 2Health News:Global Pharma Integrates Imperium(TM) to Support Launch Content ROI Initiatives! 2Health News:The Dannon Company Sponsors FitFuture KIDS Fest 2Health News:The Dannon Company Sponsors FitFuture KIDS Fest 3
(Date:4/17/2015)... 2015 Research and Markets ( ... "The Corporate Reputation of Pharma - The ... report to their offering. The ... now in its fourth edition. This report contains ... For each annual Corporate Reputation report, the author ...
(Date:4/17/2015)... April 17, 2015 Sigma-Aldrich Corporation ... Science and High Technology company, today announced the ... headquarters and state-of-the-art Cell Culture Technical Center ... facility will provide customized support to meet customer ... "Our new Technical Center will significantly ...
(Date:4/17/2015)... TWi Pharmaceuticals, Inc. ("TWi", Stock Ticker:4180.TT) today ... USA , has obtained state sales licenses from ... been in close contact with the major nationwide retail ... own label specialty generic products sold through these nationwide ... According to IMS Health, the U.S. pharma ...
Breaking Medicine Technology:The Corporate Reputation of Pharma - The Global Patient Perspective in 2014 2Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 2Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 3Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 4Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 5
... HealthCare Inc. (OTC Pink: MHCC) announced the appointment of ... Millennium President Chris Amandola commented, "Ed brings deep experience ... have him join our advisory board.  Our Company,s advantage ... and resourceful individuals and he will be a tremendous ...
... ABT ) today announced that the U.S. Food ... Self-Expanding Stent System for the treatment of iliac artery ... affects the lower extremities. Over time, iliac artery disease ... experience chronic pain and suffer permanent disability. This approval ...
Cached Medicine Technology:Millennium HealthCare Appoints Ed Joyce to Company Advisory Board 2Abbott's Absolute Pro® Vascular Self-Expanding Stent System Receives FDA Approval for Treatment of Iliac Artery Disease 2Abbott's Absolute Pro® Vascular Self-Expanding Stent System Receives FDA Approval for Treatment of Iliac Artery Disease 3Abbott's Absolute Pro® Vascular Self-Expanding Stent System Receives FDA Approval for Treatment of Iliac Artery Disease 4
Steel Knife with box for the Series 8000 Sliding Microtome. C-Profile, 240 x 33 x13m, 22 Degree angle, tapped to accept holder for Shandon knife sharpener....
... The new SureCut M3500 Radial Microtome has ... is marvelous, and a range of functions and ... users. Based on years of experience and ... innovative design the SureCut M3500 Microtome will be ...
... Radial Microtome has a look that is revolutionary, ... of functions and capabilities that will please the ... of experience and knowledge but still breaking new ... Microtome will be the answer to many of ...
Spare fuse set...
Medicine Products: