Navigation Links
Intensive care quality of sleep improved by new drug, reports study
Date:12/12/2007

A new sedative drug has been shown to improve the sleep quality and comfort levels of intensive care patients, compared to the most commonly-used medication, according to research published today in the journal JAMA.

US and UK researchers compared the effects of the new drug dexmedetomidine with the commonly used sedative lorazepam, both of which reduce the pain and anxiety experienced by mechanically ventilated ICU patients and which help them to tolerate invasive procedures such as the insertion of catheters and feeding tubes.

While the routinely-administered lorazepam successfully lessens discomfort, it has also been associated with an increased risk of brain dysfunction, including coma and delirium, which prolong patients' time in hospital and raise the chance of death.

Now trials led by researchers at Vanderbilt University Schools of Medicine and Nursing in the US have shown that dexmedetomidine can provide better sedation and analgesia whilst at the same time reducing instances of coma and delirium.

The double-blind randomised controlled trials administered either dexmedetomidine or lorazepam for up to 120 hours to 106 volunteer adult mechanically ventilated ICU patients.

They found that around 30 per cent fewer patients in the dexmedetomidine group experienced coma, and that this group also experienced an average of four more coma-free and delirium-free days over study days one to 12 than those using lorazepam.

At the same time, dexmedetomidine proved to be a more effective sedative, with 80 per cent of the dexmedetomidine group sedated to the target level over the course of the trial, compared with 67% of the lorazepam group.

The study, carried out by researchers at Vanderbilt University, Tennessee, builds on the pioneering work of Professor Mervyn Maze of Imperial College London, who discovered and patented the sedative and hypnotic properties of dexmedetomidine in 1986, whilst he was at S
'/>"/>

Contact: Laura Gallagher
l.gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Large intensive care study reveals vital recommendations for treatment of brain injury patients
2. Browns Wives Host Special Day at MetroHealth Medical Center to Support the Neonatal Intensive Care Unit
3. Smoking Cessation Rates Double With Intensive Counseling and Free Nicotine Replacement Therapy, Studies of 20,000 Smokers Show
4. More proof needed of safety and quality of electronic personal health records
5. Pitt study finds inequality in tobacco advertising
6. Poor indoor air quality means poorer health for patients with COPD
7. Kingfisher Healthcare (KFH) Achieves World Class Quality Platform
8. Exempla Healthcare Contracts For Talismans Quality Donor System
9. Study finds primary care depression treatment often does not follow quality guidelines
10. Income inequality associated with overnourishment and undernourishment in India
11. Exercise and yoga improves quality of life in women with early-stage breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... 21, 2013 Parker Waichman LLP, a ... victims injured by defective medical devices, is addressing new ... Surgery on May 15, 2013. The study found that ... complications that occur in patients with metal-on-metal hip implants ... http://www.jbjs.org/article.aspx?articleid=1684770 ) , “We’ve known for ...
(Date:5/21/2013)... CA (PRWEB) May 21, 2013 ... Annual EB-5 Investment Summit: Dealmakers Conference in Long ... Conference will focus on exploring alternative finance through ... the latest market, legal and economic information, and ... and legal professionals within the EB-5 industry. ...
(Date:5/21/2013)... AZ (PRWEB) May 21, 2013 ... and inventors who want to develop their ideas ... summer program. , The university is recruiting ... revolutionary new “formation space” that provides early-stage entrepreneurs ... While AREA48 is open to anyone, ASU is ...
(Date:5/21/2013)... 2013 The In View series ... and cable channels across the country, announces it has ... channel. The producers of the series proudly bring audiences ... industry, the manufacturing industry, health-related companies, medical facilities and ... medical practitioners in all parts of the United States, ...
(Date:5/21/2013)... May 21, 2013 Global Proving Ground ... Bodybuilding.com, the largest online retailer of health and fitness ... reality-based sports show, Warrior Island. “We cast the ... Facebook & Twitter, with our unique social networking platform,” ... these elite fighters on an island in the Pacific ...
Breaking Medicine News(10 mins):Health News:Parker Waichman LLP Comments on New Study Showing that MRI is Useful for Predicting Failure of Metal-on-Metal Hip Implants 2Health News:Parker Waichman LLP Comments on New Study Showing that MRI is Useful for Predicting Failure of Metal-on-Metal Hip Implants 3Health News:Artisan Business Group to Host EB-5 Investment Conference in Long Beach, California 2Health News:ASU Launches Summer Program for Aspiring Entrepreneurs, Innovators and Inventors 2Health News:ASU Launches Summer Program for Aspiring Entrepreneurs, Innovators and Inventors 3Health News:ASU Launches Summer Program for Aspiring Entrepreneurs, Innovators and Inventors 4Health News:In View hosted by Larry King Announces New Videos on its YouTube Channel 2Health News:Bodybuilding.com Partners with Global Proving Ground’s New Reality Show Warrior Island 2Health News:Bodybuilding.com Partners with Global Proving Ground’s New Reality Show Warrior Island 3
... ... all things eco-licious in style, mama, home, news, and food. Greenista.com,s daily emails to their ... ... Greenista ? A Greenista is a fashionista with a green conscience. Just in time for ...
... ... ... Tahitian Noni International (TNI) announced that XanGo’s parent company DBC, LLC, asked that YouTube ... video portrays multiple superfruit juices trying to attack the stable iridoids of Tahitian ...
... ... EcoBold announces its boldest move to help the green movement. ... ... is taking matters into their own hands. If they can get 1 ...
... ... Plastic Surgery Studios and Candace Crowe Design has grown into a full-fledged partnership. Through ... patient education through multimedia avenues. , ... (PRWEB) April 22, 2010 -- Plastic Surgery Studios, a total ...
... ... voluntary fee-based program tests green product performance on real-world soils. , ... Lowell, MA (PRWEB) April 22, 2010 ... the University of Massachusetts Lowell (UMass Lowell) TURI Lab as a High Performance Cleaning ...
... ... the 11th Best in the United States, , ... Pueblo of Santa Ana (PRWEB) April 22, 2010 -- Tamaya Mist Spa & Salon at the ... in the country by Condé Nast Traveler, one of the nation,s leading travel magazines. The ...
Cached Medicine News:Health News:New Eco Site, Greenista.com, Launches on Earth Day 2Health News:Whimsical Tahitian Noni International YouTube Video Yanked after Competitor Complains 2Health News:EcoBold To Plant One Million Trees 2Health News:Plastic Surgery Studios and Candace Crowe Design Create New Partnership 2Health News:IEHA and UMass Lowell Recognize Activeion as a High Performance Cleaning Product 2Health News:IEHA and UMass Lowell Recognize Activeion as a High Performance Cleaning Product 3Health News:Leading New Mexico Resort Spa At Hyatt Regency Tamaya Ranked Among The Country's Best By Conde Nast Traveler 2Health News:Leading New Mexico Resort Spa At Hyatt Regency Tamaya Ranked Among The Country's Best By Conde Nast Traveler 3
(Date:5/21/2013)... 21, 2013  NxStage Medical, Inc. (Nasdaq: ... today announced that it has entered into new agreements ... products to DaVita, the kidney care division of DaVita Healthcare ... For the use of products for home ... NxStage has executed a second amended and restated National ...
(Date:5/21/2013)... , May 21, 2013 /PRNewswire/ ... VRX ) (TSX: VRX) ... directors nominated at its 2013 annual ... results of the vote for the ... below:  NameForWithheldRonald H. Farmer235,731,9341,964,748Robert A. Ingram233,865,8763,830,806Theo ...
(Date:5/21/2013)... Massachusetts , 21. Mai 2013 /PRNewswire/ ... („OSI"), die die Firmen OMNIlife science® Inc., Enztec ... zählt, hat zwei neue, erfahrene Mitglieder in ... , eine erfahrene Führungspersönlichkeit aus der ... David Johnson , anerkannter ...
Breaking Medicine Technology:NxStage Announces New Agreements with DaVita 2Valeant Pharmaceuticals Announces 2013 Annual Meeting Results 2Orthopaedic Synergy Inc. meldet bedeutenden Zuwachs im Vorstand 2Orthopaedic Synergy Inc. meldet bedeutenden Zuwachs im Vorstand 3
... A new national survey shows that consumers are highly satisfied ... and drugstores they provide, the Pharmaceutical Care Management Association ... care most about holding down costs and are extremely skeptical ... costs. "While there is always more that ...
... product launches are continually occurring across various areas in ... the dueling goals of containing costs and producing a successful ... much to invest, and how to best spend those investments? ... launch is spent before during the launch year, with ...
Cached Medicine Technology:New Consumer Survey Finds Overwhelming Satisfaction with Pharmacy Benefits 2Launch Spend Insights: Companies Now Invest More in Launch Year Than in Previous 3 Ramp-Up Years Combined 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: