Navigation Links
Intensive Insulin Therapy Reduces Mortality in Sick Kids
Date:1/27/2009

Lowering blood glucose levels also cut time in ICU, study finds

TUESDAY, Jan. 27 (HealthDay News) -- Intensive insulin therapy may reduce the risk of death, infection and the length of intensive care stays for seriously ill children, a European study suggests.

Abnormally high blood sugar (hyperglycemia) often occurs in critically ill infants and children, and increases their risk of secondary infections and death.

This study included 700 critically ill patients -- 317 infants under 1 and 383 children aged 1 to 16 years. They were randomly assigned to receive either intensive insulin treatment to reduce their blood glucose level to its normal level or to receive insulin treatment only if their blood glucose level reached dangerously high levels (conventional therapy).

Mean blood glucose concentrations were lower among those who received the intensive therapy than among those who received conventional therapy. More children in the intensive therapy group developed hypoglycemia (abnormally low blood sugar), but they had a lower death rate (3 percent vs. 6 percent) and a shorter intensive care stay (5.5 days vs. 6.1 days) than those in the conventional therapy group.

The findings were expected to be published in an upcoming issue of The Lancet.

"Targeting of blood glucose concentrations to age-adjusted normal fasting concentrations improved short-term outcome of patients in pediatric intensive care units. The effect on long-term survival, morbidity, and neurocognitive development needs to be investigated," Dr. Greet Van den Berghe, of University Hospital Gasthuisberg and Catholic University Leuven, Belgium, and colleagues wrote in a journal news release.

More research into this type of treatment is needed, Dr. Mitchell M. Levy, of Brown University and Rhode Island Hospital, and Dr. Andrew Rhodes, of St. George's Healthcare NHS Trust in the United Kingdom, wrote in an accompanying commentary.

"Clinicians must take into account several factors, including the nature of the intensive-care population in their institution and the incidence of hypoglycemia with local insulin protocols when determining what glucose target is most appropriate for their critically ill patients. Perhaps the results of ongoing large-scale trials will provide greater clarity for this clinical dilemma," Levy and Rhodes wrote.

More information

The Nemours Foundation offers information for parents of children in the ICU.



-- Robert Preidt



SOURCE: The Lancet, news release, Jan. 27, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Intensive support programs can help hospitalized smokers stay smoke-free
2. Integrated Medical Systems Receives FDA Clearance for Worlds First Suitcase Intensive Care Unit
3. New Intensive Care Unit at Gilbert Hospital Sees First Patient
4. WellPoint Partners With CareNex Health Services to Expand Its Neonatal Intensive Care Services Program
5. Newborns in Intensive Care Often Exposed to Pain
6. Less Intensive Treatment Given Diabetic Women With Heart Disease
7. Cystic Fibrosis Foundation Hosts Quality Improvement Summit - Caregivers from 15 States and Canada Gather in Hartford for Intensive Learning
8. More intensive dialysis does not improve outcomes among patients with acute kidney injury
9. Mayo Clinic Research Shows U.S. Intensive Care Units Prevention of Pneumonia in Critically-ill Patients Generally Strong; Identifies Area of Improvement
10. Intensive care units prevention of pneumonia in critically-ill patients generally strong
11. Construction Commencing at Gilbert Hospitals New Intensive Care Unit
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Intensive Insulin Therapy Reduces Mortality in Sick Kids
(Date:9/21/2017)... Falls Church, VA (PRWEB) , ... September 21, ... ... Use Policy , **An FDAnews Management Report**, http://www.fdanews.com/products/54818-promotional-communication      , In the ... every edge they can get while staying in compliance with FDA rules. , ...
(Date:9/21/2017)... WA (PRWEB) , ... September 21, 2017 , ... ... technology using Microscan’s LVS 7510 at the Global GS1 Healthcare Conference 2017 in ... of the life-sciences industry for ensuring label quality and improving patient safety. ...
(Date:9/21/2017)... ... September 21, 2017 , ... FlipBelt, the fitness brand that ... detail to the athletic wear market with the launch of their FlipBelt Crops. , ... their essentials securely at their fingertips while at the gym, on the trail, or ...
(Date:9/20/2017)... ... September 20, 2017 , ... FirstAlign ( http://www.firstalign.com ), combines ... Artificial Intelligence (AI) thinking, announced today the launch of its revamped web presence. ... information that offers a more comprehensive understanding of the organization’s business and machine ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... and commercialization, has just released a new white paper discussing the benefits ... than ever about medical device, pharmaceutical, and combination product organizations making sure ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)...   BioLife Solutions , Inc. (NASDAQ: BLFS ... grade cell and tissue hypothermic storage and ... , President and CEO, will be presenting at two investment ... Renshaw 19 th Annual Global Investment Conference on Tuesday, ... time). The conference is being held at the New York ...
(Date:9/6/2017)... , Sept. 6, 2017   PDI , a ... it will host an educational session focused on the ... infection (CLABSI) prevention at the 2017 Annual Scientific Meeting ... will take place at the Phoenix ... from Sept. 16-19, will also feature PDI,s ...
(Date:9/5/2017)... -- Sapheneia and Scannerside received FDA 510(k) clearance to ... third-party Vendor neutral CT product that makes it affordable ... current MITA standards. ... specifically designed to provide CT operators, prior to a ... a predefined threshold. Scannerside Dose Check is intended to ...
Breaking Medicine Technology: