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Insulin Resistance Tied to Peripheral Artery Disease
Date:6/16/2008

-IR quartiles, supporting prior observations that PAD is associated with the metabolic syndrome and glucose intolerance, both surrogate markers of insulin resistance.

"Further, the association persisted after adjustment for diabetes or hemoglobin A1c, another measure of blood sugar control, indicating that insulin resistance may play a role in PAD along the entire spectrum of insulin resistance, quite distinct from the impact of diabetes," Pande said.

The study was published in the journal Circulation.

"For doctors and patients, our study highlights the role of insulin resistance in PAD and gives us a snapshot of the association between the two diseases," Pande said. "For this to play out, however, we still need prospective studies that follow over time insulin-resistant patients to determine their risk of developing PAD."

More information

The U.S. National Heart, Lung, and Blood Institute has more about peripheral arterial disease.



-- Robert Preidt



SOURCE: American Heart Association, news release, June 16, 2008


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