Navigation Links
Insulin-Linked Hormone May Also Raise Alzheimer's Risk
Date:1/3/2012

TUESDAY, Jan. 3 (HealthDay News) -- Rising levels of a hormone associated with sensitizing the body to insulin appears to raise the risk for developing dementia and Alzheimer's among women, new research reveals.

The hormone in question, adiponectin, is derived from visceral fat. It is known to play a role in regulating the metabolism of glucose and lipids, while also carrying certain anti-inflammatory characteristics.

So, the finding is therefore somewhat unexpected, given that insulin resistance and inflammation are considered to be hallmarks of both type 2 diabetes and Alzheimer's disease (AD). The logical presumption would have been that anything that lowers insulin resistance and inflammation might also reduce the risk for dementia.

Study leader Thomas van Himbergen, of the Lipid Metabolism Laboratory with the Human Nutrition Research Center on Aging at Tufts University in Boston, and his colleagues report their finding online Jan. 2 in the Archives of Neurology.

"It is well established that insulin signaling is dysfunctional in the brains of patients with AD, and since adiponectin enhances insulin sensitivity, one would also expect beneficial actions protecting against cognitive decline," van Himbergen said in a journal news release. "Our data, however, indicate that elevated adiponectin level was associated with an increased risk of dementia and AD in women."

The authors note that the global incidence of dementia is projected to double over the next two decades, at which point it will affect roughly 72 million people.

To get at possible mechanism and indicators of the onset of Alzheimer's, the team took blood samples from 541 women over the course of 13 years. The samples were measured for levels of a number of markers, including glucose, insulin and adiponectin. All patients were simultaneously monitored for dementia symptoms.

During the study, 159 patients went on to develop dementia, of which 125 were Alzheimer's cases.

In the end, the investigators concluded that only a rise in adiponectin signaled an increased risk for both all-cause dementia and/or Alzheimer's.

More information

For more on dementia, visit the Alzheimer's Association.

-- Alan Mozes

SOURCE: Archives of Neurology, news release, Jan. 2, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Pioneering Hormone Therapist to Host Free Health Seminar
2. Hormone May Prevent Aggressive Breast Cancer
3. Bonding Hormone Might Help Some With Autism
4. WHI data confirm short-term heart disease risks of combination menopausal hormone therapy
5. Early On, Hormone Therapy May Raise Womens Heart Risks
6. Testicular Cancer Survivors May Have Hormone Deficiency
7. Stress hormone, depression trigger obesity in girls
8. Buy HGH Website Educates Consumers on the Pros and Cons of Human Growth Hormone Supplements
9. Hormone thought to slow aging associated with increased risk of cancer death
10. Hormone Outperforms Insulin in Diabetic Mice
11. High Hormone Level Linked to Cancer Death in Older Men
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Insulin-Linked Hormone May Also Raise Alzheimer's Risk 
(Date:10/13/2017)... ... October 13, 2017 , ... ... (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along ... updates for the primary prevention of cardiovascular diseases during the 15th Annual ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that covers care ... have a waiver for care if the client has a cognitive impairment diagnosis. ... for care, is often waived, so the benefits from their insurance start immediately,” said ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun Run ... This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed ... geared towards children of all ages; it is a non-competitive, non-timed event, which is ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, ... Development, has been awarded a contract by the Center for Medicare and Medicaid ... to accelerate the enterprise use of Agile methodologies in a consistent and high ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... for healthcare compliance program management, will showcase a range of technology and learning ... Assisted Living (NCAL) Convention and Expo to be held October 14–18, 2017 at ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... KALAMAZOO, Mich. , Sept. 18, 2017  PMD ... OptiMed Specialty Pharmacy of Kalamazoo, Mich. ... strategic hub service that expedites and streamlines patient and ... Spiro PD 2.0, and wellness management services.  ... medical device used to measure lung function for a ...
(Date:9/12/2017)... and NEW YORK , Sept. 12, 2017 /PRNewswire/ ... ratings for global supply chains, has published the first annual edition of ... performance of more than 20,400 companies evaluated by EcoVadis, based on Scorecard ... and 2016. ... Global CSR Risk & Performance Index ...
(Date:9/9/2017)... , Sept. 8, 2017 ... Mobile MRI Unit coming to Washington DC ... When: Tuesday, September 12 th – Monday, September 18 ... D.C. offering free MRI brain scans to the public.Where:  ... be parked at 501 K Street NW, Washington, D.C.What:BTF brings its nationwide ...
Breaking Medicine Technology: