Navigation Links
Insulin-Linked Hormone May Also Raise Alzheimer's Risk
Date:1/3/2012

TUESDAY, Jan. 3 (HealthDay News) -- Rising levels of a hormone associated with sensitizing the body to insulin appears to raise the risk for developing dementia and Alzheimer's among women, new research reveals.

The hormone in question, adiponectin, is derived from visceral fat. It is known to play a role in regulating the metabolism of glucose and lipids, while also carrying certain anti-inflammatory characteristics.

So, the finding is therefore somewhat unexpected, given that insulin resistance and inflammation are considered to be hallmarks of both type 2 diabetes and Alzheimer's disease (AD). The logical presumption would have been that anything that lowers insulin resistance and inflammation might also reduce the risk for dementia.

Study leader Thomas van Himbergen, of the Lipid Metabolism Laboratory with the Human Nutrition Research Center on Aging at Tufts University in Boston, and his colleagues report their finding online Jan. 2 in the Archives of Neurology.

"It is well established that insulin signaling is dysfunctional in the brains of patients with AD, and since adiponectin enhances insulin sensitivity, one would also expect beneficial actions protecting against cognitive decline," van Himbergen said in a journal news release. "Our data, however, indicate that elevated adiponectin level was associated with an increased risk of dementia and AD in women."

The authors note that the global incidence of dementia is projected to double over the next two decades, at which point it will affect roughly 72 million people.

To get at possible mechanism and indicators of the onset of Alzheimer's, the team took blood samples from 541 women over the course of 13 years. The samples were measured for levels of a number of markers, including glucose, insulin and adiponectin. All patients were simultaneously monitored for dementia symptoms.

During the study, 159 patients went on to develop dementia, of which 125 were Alzheimer's cases.

In the end, the investigators concluded that only a rise in adiponectin signaled an increased risk for both all-cause dementia and/or Alzheimer's.

More information

For more on dementia, visit the Alzheimer's Association.

-- Alan Mozes

SOURCE: Archives of Neurology, news release, Jan. 2, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Pioneering Hormone Therapist to Host Free Health Seminar
2. Hormone May Prevent Aggressive Breast Cancer
3. Bonding Hormone Might Help Some With Autism
4. WHI data confirm short-term heart disease risks of combination menopausal hormone therapy
5. Early On, Hormone Therapy May Raise Womens Heart Risks
6. Testicular Cancer Survivors May Have Hormone Deficiency
7. Stress hormone, depression trigger obesity in girls
8. Buy HGH Website Educates Consumers on the Pros and Cons of Human Growth Hormone Supplements
9. Hormone thought to slow aging associated with increased risk of cancer death
10. Hormone Outperforms Insulin in Diabetic Mice
11. High Hormone Level Linked to Cancer Death in Older Men
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Insulin-Linked Hormone May Also Raise Alzheimer's Risk 
(Date:6/26/2016)... ... 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment ... Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This ... of the world’s leading providers of cereal and other breakfast foods. Its residents often ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his ... David Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps ... in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set ... drug or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, ... traumatic event. , Trauma sufferers tend to feel a range of emotions, from depression, ...
(Date:6/24/2016)... Francisco, CA (PRWEB) , ... June 24, 2016 ... ... CitiDent, is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive ... self-ligating Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
(Date:6/23/2016)... LONDON , June 23, 2016 ... environments  Oticon , industry leaders in ... the launch of Oticon Opn ™, the world,s ... world of possibilities for IoT devices.      ... Opn, Oticon introduces a number of ,world firsts,: ...
Breaking Medicine Technology: