Navigation Links
Institute for Aging Research study finds delirium presentation predicts mortality
Date:7/6/2009

(Boston, Mass)The way certain patients present in the post-acute hospital setting with delirium, a common, preventable but life-threatening acute confusional state, predicts mortality, according to a study conducted by the Institute for Aging Research of Hebrew SeniorLife.

Patients with severe, hypoactive delirium, characterized by slowing or lack of movement and unresponsiveness, have the worst six-month survival rate of any class of the disease. Those with mild, hypoactive delirium have a significantly higher likelihood of dying than patients with other, milder symptoms.

"The association of the delirium classes on mortality depends on the presence or absence of dementia," says lead author Frances Yang, Ph.D., an assistant scientist at the Institute for Aging Research and an instructor in psychiatry at Brigham and Women's Hospital and Harvard Medical School. "Among patients who did not have dementia, it was delirium severity rather than motoric subtype that was associated with higher risk of mortality at six months."

The study, published in the May/June issue of the journal Psychosomatics, is the first to link characteristics of delirium, called subtypes, with disease severity. The four subtypes of delirium are normal, hypoactive, hyperactive (symptoms range from mild restlessness to constant movement and agitation) and mixed, which combines both hypo- and hyperactive elements.

Using two standard assessment tools, researchers at the Institute's Aging Brain Center examined whether the classic psychomotor subtypes of delirium are reflected by delirium severity. In addition, they sought to determine if the subtypes were able to predict mortality.

Dr. Yang's co-author, Edward Marcantonio, M.D., an associate professor of medicine at Beth Israel Deaconess Medical Center and Harvard Medical School, and colleagues screened more than 4,000 patients at eight Boston-area skilled nursing facilities using the Confusion Assessment Method and the Memorial Delirium Assessment Scale, two standard tools to detect delirium. More than 400 of these patients were found to have delirium and were followed over six months.

Delirium is an acute and relatively suddenover hours or daysdecline in attention, perception and cognition. It is generally caused by severe physical illness, often in the elderly, or any process that interferes with the normal metabolism and function of the brain. An estimated 14 percent to 24 percent of patients admitted to the hospital suffer from episodes of delirium. A recent study by Aging Brain Center investigators found that delirium rapidly accelerates memory decline in Alzheimer's disease patients.

"Our data reinforce the need to systematically assess patients for delirium at post-acute care admission, while considering dementia status," says Dr. Yang. "The findings demonstrate the importance of examining psychomotor subtype and the severity of delirium in predicting mortality."


'/>"/>

Contact: Scott Edwards
Edwards@hrca.harvard.edu
781-247-8172
Hebrew SeniorLife Institute for Aging Research
Source:Eurekalert

Related medicine news :

1. The Risk Management and Patient Safety Institute Announces Annual Health Care Risk Conference Dates
2. Mayo Clinic Multidisciplinary Simulation Center Receives Distinction as an ACS-Accredited Education Institute
3. LifeNet Health Establishes The Skin & Wound Allograft Institute
4. Statement from Employment Policies Institute on Senator Hillary Clintons Health Care Plan
5. CAS Medical Systems, Inc. Awarded $2.8 Million Grant by National Institutes of Health
6. Portico Systems to Share Provider Network Management Best Practices at Institute for International Research
7. The Integrated Benefits Institute Offers Largest Benchmarking Database in U.S. Spanning Disability and Workers Compensation Programs
8. The Cooper Institutes FITNESSGRAM Selected as Statewide Physical Fitness Assessment Tool
9. Bullying Prevention Institute Designed to Empower Change in Schools
10. Southern Research Institutes Neurodegenerative Disease Drug Discovery Program Receives National Institute of Mental Health Funding
11. Corey McPherson Nash Develops Case Statement for Dana-Farber Cancer Institute Capital Campaign
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2017)... ... 2017 , ... Drs. Steven White and Brad Haines are pleased to announce ... of this offer, valued at more than $300 per year, new patients can enjoy ... patients receive a complimentary professional whitening procedure. , Stained or yellowed tooth enamel ...
(Date:8/23/2017)... ... 2017 , ... Nightingale College continues the semiannual Give Back Day tradition for ... College dedicates to serving and volunteering for organizations that provide indispensable resources to the ... that need a little extra help. , The College’s Give Back Day initiative ...
(Date:8/23/2017)... ... August 23, 2017 , ... MobilityWorks ®, the nation's ... the 2017 Inc. 500|5000, an exclusive ranking of America’s fastest-growing private companies. MobilityWorks ... percent, marking the twelfth year that the company has been included on the ...
(Date:8/23/2017)... ... August 23, 2017 , ... ... (SNAC) is holding an inaugural State of the Science Symposium in partnership ... Wednesday, Sept. 20, 2017. , This symposium provides a forum for global leaders ...
(Date:8/22/2017)... NASHVILLE, Tenn. (PRWEB) , ... August 22, 2017 ... ... Company, is pleased to announce the addition of Zack Tisch as the ... services for the KLAS-ranked healthcare IT consulting firm’s national accounts, from assisting clients ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... Mich., Aug. 7, 2017  Diplomat Pharmacy, Inc. (NYSE: DPLO), ... the quarter ended June 30, 2017.  All comparisons, unless otherwise ... Second Quarter 2017 Highlights ... to $1,089 million, an increase of 3.5% ... Gross margin of 7.5% versus 7.6% ...
(Date:8/4/2017)... , Aug. 4, 2017 The search ... shortly after a physician/patient consult has long been the ... was a notable focus of the largest meeting of ... according to healthcare market research firm Kalorama Information.  The ... testing (POCT) offerings or related supplies and software were ...
(Date:8/3/2017)... , Aug. 3, 2017  Opioid addiction and other ... up healthcare costs and threatening outcomes, were problems taken ... and IVD industry that support them, met this week. ... researcher said that drugs of abuse, procalcitonin and acute ... at the organization,s 69th meeting in San ...
Breaking Medicine Technology: