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Inspire Medical Systems Completes First Implant of the Inspire II System to Treat Obstructive Sleep Apnea
Date:2/26/2009

MINNEAPOLIS, Feb. 26 /PRNewswire/ -- Inspire Medical Systems, Inc., a private medical device company, today announced it has completed the first human implant of its Inspire II system designed to treat Obstructive Sleep Apnea (OSA).

It is estimated that one in fifteen adults has moderate to severe OSA(1). People with OSA experience recurrent blockage of their upper airway during sleep, resulting in frequent arousals from sleep and reduced oxygen levels in the blood. This happens in patients with OSA because the muscles that normally hold the airway open during wakefulness relax during sleep and allow the airway to collapse. When the airway is partially closed and/or the muscles relax too much, trying to inhale will completely close the airway, resulting in an obstructive sleep apnea event. Depending on the degree of severity, OSA is a potentially life-threatening condition. According to a recent report(2) from the National Center on Sleep Disorders Research and the National Institute of Health, someone who has undiagnosed or is non-compliant to treatment of their sleep apnea is significantly more likely to have a heart attack, a stroke, cardiac arrest during sleep, or a harmful accident.

The Inspire II system is an implantable device that delivers electrical stimulation to prevent the closure of the upper airway that can stop airflow in patients with OSA. The device is a unique closed-loop system that is able to sense respiratory effort and deliver stimulation to keep the airway open and breathing normal.

Inspire Medical Systems collaborated with Paul Van de Heyning, M.D., professor of Otorhinolaryngology and Head and Neck surgery and Wilfried De Backer, M.D., professor of Respiratory Medicine both at the University Hospital in Antwerp, Belgium for the first patient implant as part of the Inspire II clinical study. The company has also received approval from the U.S. Food and Drug Adminis
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SOURCE Inspire Medical Systems, Inc.
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