Navigation Links
Insomnia after myocardial infarction
Date:12/1/2010

This release is available in French.

Montreal, December 1st, 2010 The heart and the brain appear to be even more closely connected than previously imagined. The damaging effects of myocardial infarction are apparently not confined to the heart, but also affect the brain. In fact, infarction seems to cause neuron loss at the level of the brainstem, which leads to insomnia, notably paradoxical insomnia. Sleep plays a crucial role in post-infarction remission, as demonstrated by the team of Roger Godbout, Ph.D., his colleague Guy Rousseau and their student Thierno Madjou Bah, investigators at the Research Center of the Hpital du Sacr-Cur de Montral, in a new study published today in the scientific journal SLEEP.

Although insomnia has long been observed following infarction, to date there have been no studies explaining the phenomenon in scientific terms, apart from the stress that is doubtless brought on by the heart attack. "Thanks to this study, we have been able to show that there is indeed a physiological explanation the death of cells that play a key role in sleep," says the researcher, who is also a full professor in the Department of Psychiatry at the Universit de Montral.

In the two weeks following a myocardial infarction, not only have periods of paradoxical sleep been observed to be less frequent and of shorter duration, but there are fewer cholinergic neurons in the brainstem, which control paradoxical sleep, due to the phenomenon of self-destruction of cells, known as apoptosis.

Treating insomnia to help the heart heal

A previous study also conducted by the team of Godbout and Rousseau demonstrated that myocardial infarction affected the limbic system, a region of the brain that is responsible for mood, which explains the depression frequently observed after heart attacks. "Since depression is frequently accompanied by insomnia, we wanted to verify whether the neurons in the brainstem were also affected," the investigator explained.

As demonstrated in this study, myocardial infarction, in addition to causing depression, is also associated with the release of factors that provoke the inflammation of tissues, including the brain, and specifically the regions that control sleep, notably the paradoxical sleep phase. The particular function of that phase is to activate regions in the brain that are responsible for integrating our emotions. If that is affected, the risk of depression also increases.

Poor-quality sleep is a known risk factor for cardiovascular disease. Since it can affect remission after an infarction, the risk of complications and recidivism rises and a vicious circle may be set in motion.

Godbout says this study illustrates the importance of rapid intervention in the days following the infarction, before the first signs of insomnia and depression are even apparent. He notes that "any preventive, pharmacological or behavioural treatment is certainly a pathway that should be considered."


'/>"/>

Contact: Vronique Allaire
veronique.allaire.hsc@ssss.gouv.qc.ca
514-338-2222 x2473
University of Montreal
Source:Eurekalert

Related medicine news :

1. Loud snoring and insomnia symptoms predict the development of the metabolic syndrome
2. Study finds an increased risk of death in men with insomnia and a short sleep duration
3. New study suggests tart cherry juice can be a natural solution for insomnia
4. Brain Balancing Gives Hope for Sufferers of Depression, Stress, and Insomnia at New Life Brain Center
5. Mammals Grew Big After Dinosaurs Died Off: Analysis
6. Kids ER Visits Down After Cold Medicine Withdrawal
7. Assessment tool predicts blood clot risk after plastic surgery
8. HIV Patients Do Well After Kidney Transplants: Study
9. Higher Plavix Dose Wont Boost Outcomes After Stent Placement: Study
10. Sponges, Surgical Tools Sometimes Left in Kids After Operation
11. Research uncovers extensive natural recovery after spinal cord injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2017)... ... May 26, 2017 , ... Somnoware, ... NOX-T3 portable sleep monitor with its Somnoware Sleep Device Interface (SDI). Somnoware SDI ... diagnostic device operations. With this platform, initializing devices and importing studies are just ...
(Date:5/26/2017)... ... May 26, 2017 , ... Boar’s Head Brand®, one ... for Memorial Day entertaining that are sure to satisfy your guests’ flavor cravings, ... meats and cheeses featured in these refreshingly balanced recipes are packed with flavor, ...
(Date:5/26/2017)... ... ... On May 24, the Congressional Budget Office (CBO) projected that the amended American ... result in 23 million Americans losing their health insurance by 2026 as compared with ... Care Act (ACA). , “It is clear from the CBO analysis that the ...
(Date:5/26/2017)... Texas (PRWEB) , ... May 26, 2017 , ... Yisrayl ... a new publication this week that is focusing on the Peace Agreements being discussed ... his Middle East sprint in a race to try to speed up peace talks ...
(Date:5/26/2017)... ... May 26, 2017 , ... Rob Lowe acts as ... production of the series is on hiking in American. Viewers can reconnect with America ... great benefits of hiking. , Many consumers have looked for an inventive new place ...
Breaking Medicine News(10 mins):
(Date:5/6/2017)... , May 5, 2017  Hill-Rom Holdings, Inc. (NYSE: ... approximately 100,000 square feet to its Welch Allyn campus. ... its commitment to bring more than 100 new jobs ... Welch Allyn has maintained a significant presence for more ... these new positions, a large portion of which will ...
(Date:5/4/2017)... Clarius Mobile Health, a digital healthcare ... this week at the American Congress of Obstetricians ... San Diego, CA from May ... perfect tool for clinicians to easily confirm pregnancy, ... pregnancy-related complications like ectopic pregnancy and placenta previa," ...
(Date:5/4/2017)... , May 4, 2017  A new ... thermoplastics and other highly-engineered materials, is being launched ... tubing has been developed in recent years to ... therapies and surgical applications. More expensive materials such ... produce microextrusion tubing due to their ability to ...
Breaking Medicine Technology: