Navigation Links
Innovator Award to Berkeley Lab's Joe Gray for improved breast cancer screening
Date:10/1/2007

ursor lesions by their molecular characteristics. To map these lesions with precision to insure successful surgery, tissue sections will be imaged using mass spectrometry to find cells that express the genes specifically associated with the most lethal cancer types.

Getting down to specifics, cell by cell

For cell-specific anatomical imaging, Gray and collaborators Matthew Francis of UC Berkeley and Berkeley Lab, Jim O'Neil and Scott Taylor of Berkeley Lab, and James Marks of UC San Francisco will investigate PET and MRI using agents carried in viral capsids. Capsids are the shells of viruses whose RNA genomes have been removed; the capsids are used to carry reagents that increase image contrast. The outside of the shells will be decorated with antibodies specifically targeting the protein gene products characteristic of the lethal cancer subtypes.

In addition, the researchers will consider quantum dots, nanocrystals that have been modified to bind to specific molecules and fluoresce when illuminated by a laser, or to increase the strength of MRI signals when combined with marker atoms. Laura Esserman, Karla Kerlikowske, and Nola Hylton at UC San Francisco and Damir Sudar at Berkeley Lab will also explore ways to improve conventional MRI and x-ray mammography by developing digital imaging algorithms that can better recognize metastasis-prone lesions.

For sensitive histopathologic detection -- the precise mapping of lesions and tumors -- Gray will work with Marks and Richard Baehner of UCSF and Frank Chen of Berkeley Lab to develop in situ hybridization and immunohistochemical techniques to identify protein products typical of the genomes of the most lethal cancer subtypes. In collaboration with James Felton at Livermore, they will analyze these molecular signatures by scanning the tissue sample with an ion beam to knock off constituent molecules, which differ by mass; this "secondary ion mass spectrometry" of the tissue
'/>"/>

Contact: Paul Preuss
paul_preuss@lbl.gov
510-486-6249
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Award for TTK Chitra heart valve prosthesis
2. Ranbaxy Pharmaceuticals Inc awarded the prestigious outstanding supplier award received from Wal-Mart
3. Magsaysay Award for Dr.Shanta from Chennai Cancer Institute
4. Scientists Awarded Appropriately For Contribution Towards Medical Research
5. Aussie Nobel Prize Winners Receive Their Awards
6. Distinguished Scientist Award Conferred on Manchester Dentist
7. Distinguished Scientist Award Conferred on University of Rochester Scientists for Work on Preventing Cavities
8. $ 1.7 Million NYSTAR Award for Binghamton University to Flex Electronics Research Muscle.
9. John Mendelsohn M.D, chosen for an International Award
10. OpenMED Nominated For Stockholm Challenge 2006 Award
11. Prestigious Gairdner Awards for medical research in 2006 Goes To Two Yale biologists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... July 28, 2014 UT Southwestern Medical ... selectively and irreversibly interferes with the activity of ... of tumors. , The molecule, SML-8-73-1 (SML), interferes ... viral oncogene homolog. The gene produces proteins called ... K-Ras can result in normal cells dividing uncontrollably ...
(Date:7/28/2014)... 28, 2014 Lourdes Health System has ... and reduced wait times for veterans needing medical care. ... in the state—and the only one in Camden, Burlington ... Community Care program (PC3). PC3 gives veterans access to ... cannot provide services due to lack of available specialists, ...
(Date:7/28/2014)... July 28, 2014 The report, ... & Geography - Trends and Forecasts to 2019” ... with analysis and forecasting of the global consumption ... market data tables with 39 figures spread through ... Market"., http://www.marketsandmarkets.com/Market-Reports/blowing-agents-market-71329121.html , Blowing agents are ...
(Date:7/28/2014)... 28, 2014 The American ... of professionals engaged in the field of organ ... Transplantation and Immunology Research Network (TIRN), a ... research. As modern organ transplantation continues to diversify, ... could provide more opportunities for physicians, scientists and ...
(Date:7/28/2014)... with one of the UK,s most common respiratory diseases ... pulmonary disease (COPD) is the name for a collection ... damage to the lungs. Often linked to smoking, ... hospital admissions in the UK, with a high proportion ... discharged. , A team of researchers, led ...
Breaking Medicine News(10 mins):Health News:UTSW cancer researchers identify irreversible inhibitor for KRAS gene mutation 2Health News:Lourdes Expands Military Partnership with Veterans 2Health News:Lourdes Expands Military Partnership with Veterans 3Health News:Blowing Agents Market is Poised to Reach 452.0 Kilotons at CAGR of 5.8% by 2019 – Report by MarketsandMarkets 2Health News:Blowing Agents Market is Poised to Reach 452.0 Kilotons at CAGR of 5.8% by 2019 – Report by MarketsandMarkets 3Health News:Blowing Agents Market is Poised to Reach 452.0 Kilotons at CAGR of 5.8% by 2019 – Report by MarketsandMarkets 4Health News:American Society of Transplantation (AST) Launches Transplantation and Immunology Research Network (TIRN); Aims to Expand Research Collaboration & Funding 2Health News:American Society of Transplantation (AST) Launches Transplantation and Immunology Research Network (TIRN); Aims to Expand Research Collaboration & Funding 3Health News:New research to tackle treatment for lung disease 2Health News:New research to tackle treatment for lung disease 3
... Children,s Research Hospital investigators have found that an electrically ... is critical to the acute hearing of humans and ... how hearing loss can result from malfunction of this ... drugs such as aspirin. , Sound entering the cochlea ...
... $12 Million in Series A First Tranche Financing, ... Capital announced,today the formation of ACT Biotech Inc., a ... drugs. ACT Biotech has,entered into a license agreement with ... stage oncology assets. In conjunction with the,agreement, ACT has ...
... Reality, MANHATTAN BEACH, Calif., May 7 A ... 2006 continues,today with open hearings and fact-finding in California. ... how homecare and nursing home,workers in the long term ... greatest strength to win for their families and the,clients ...
... MECHANICSBURG, Pa., May 7 Select Medical Corporation,will release ... 31,2008 on Thursday, May 15, 2008., The Company ... on Wednesday, May 21, 2008, at 11:00am EDT. The ... international dial in number is,1-210-839-8503. The passcode for the ...
... neural development, mouse study shows , , WEDNESDAY, May 7 ... that suppresses appetite by blocking cannabinoid receptors in the ... scientists report. , In research with mice, they found ... of the brain necessary for neural development in young ...
... may increase adults risk for having dementia, according to ... Health. Their analysis of published obesity and dementia ... a consistent relationship between the two diseases. The results ... of Obesity in the May, 2008 issue of Obesity ...
Cached Medicine News:Health News:St. Jude finds 'dancing' hair cells are key to humans' acute hearing 2Health News:St. Jude finds 'dancing' hair cells are key to humans' acute hearing 3Health News:ACT Biotech Acquires Clinical and Early Stage Oncology Portfolio Licenses From Bayer Healthcare 2Health News:Open Hearings, Fact-Finding Today by SEIU Long Term Care Workers Continues Democratic Process Begun in 2006 2Health News:Obesity linked to increased risk for dementia 2
(Date:7/25/2014)... , July 25, 2014  Corporate libraries are ... understanding new advancements in technology and how to cope ... libraries in the pharmaceutical and medical device industries are ... the information and services they provide. ... LLC there are many forces of change that leading ...
(Date:7/25/2014)... /PRNewswire-iReach/ -- "Australia Capsule Endoscopy Systems Market Outlook to ... Endoscopy Systems market. The report provides value, in millions ... (in US dollars) within market segments: Photo ... Endoscopes , Capsule Endoscopy Data Recorders , ... provides company shares and distribution shares data for each ...
(Date:7/25/2014)...  Smile Train and its technology partner BioDigital have ... Simulator among leading global health innovations in The Hive ... Washington, D.C. at The John F. ... "Smile Train is honored to be represented through our ... in health and medicine that TEDMED unites each year," ...
Breaking Medicine Technology:Forces of Change Reshaping Corporate Libraries & Information Services 2Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 2Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 3Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 4Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 5Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 2Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 3