Navigation Links
Injection May Heal Damaged Heart
Date:7/23/2009

In mouse study, injured tissue and coronary function are restored

THURSDAY, JULY 23 (HealthDay News) -- Doctors have been unable to help injured heart tissue renew itself after a heart attack -- until now.

During a heart attack, vessels that supply blood to the heart become blocked, preventing enough oxygen from getting through. The heart muscle dies or is permanently damaged.

But researchers at Children's Hospital Boston report progress toward someday being ale to regenerate heart tissue after a heart attack or heart failure and even in children who are born with congenital heart defects.

In a study on mice, they showed that neuregulin 1 (NRG1), a growth factor involved in the development of the heart and nervous system, can fuel heart-muscle growth and recovery of cardiac function when injected after a heart attack.

This is a significant development because coronary heart disease, which causes heart attack and angina, is the leading cause of death in America.

After birth, heart-muscle cells stop dividing and proliferating. But experts, led by Dr. Bernhard Kuhn and Kevin Bersell of the cardiology department at Children's, restarted the cell cycle with NRG1, spurring the heart-muscle cells to divide and make copies of themselves.

When the team injected NRG1 into live mice once a day for three months after the animals had heart attacks, heart regeneration increased and the pumping function improved, compared with untreated mice.

In addition, the NRG1-injected mice did not show some common aftereffects of heart failure.

The study, funded by the cardiology department at Children's Hospital Boston, the Charles Hood Foundation and the American Heart Association, found that cell growth does not have to come from stem cells. A report on the research appears in the July 24 issue of Cell.

"Although many efforts have focused on stem cell-based strategi
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Investigational New Drug Application for Fat Melting Injections Cleared by the FDA
2. HCV and HBV spreading more slowly among injection drug users in San Francisco
3. Microbiotic technology developed for microinjection of zebrafish embryos
4. Pill Equals Injection in Preventing Clots After Hip Replacement
5. Multiple corticosteroid injections in pregnant women may increase cerebral palsy
6. Consumer Safety Alert on Fat Dissolving Injections
7. FDA Expands VELCADE(R) (Bortezomib) for Injection Label for Patients with Multiple Myeloma
8. MultiVu Video Feed: FDA Approves DORIBAX(TM) (doripenem for injection) for the Treatment of Complicated Intra-abdominal and Complicated Urinary Tract Infections
9. Ultrasound-guided injections help ease chronic Achilles tendon pain
10. New Taxotere(R) (docetaxel) Injection Concentrate Data to be Presented at the 30th Annual San Antonio Breast Cancer Symposium (SABCS)
11. Highest Reported Complete Remission Rate of 35 Percent Achieved in a Phase III Front-Line Multiple Myeloma Trial With Velcade(R) (Bortezomib) for Injection Based Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Injection May Heal Damaged Heart
(Date:12/21/2014)... December 21, 2014 CannabisClassifieds.com celebrates marijuana’s new ... The only one of its kind, the site has provided ... marijuana for 14 years running. It uniquely combines the ... make cannabis readily available to the masses. Assuring the ... the golden ring of public approval. , Shane ...
(Date:12/20/2014)... MissyDress, a distinguished special dress supplier, has just ... has drastically cut prices to all its prom dresses ... 30, 2015. Many of the hottest styles are sold ... dresses, and more. , A spokesman for MissyDress says, ... A-line princess prom dresses or sweetheart chiffon prom dresses, ...
(Date:12/20/2014)... The print component of Healthy Aging is distributed ... 160,000 copies and an estimated readership of 420,000. The ... media strategy and across a network of top news ... of the campaign, click here . , The ... of CTV’s The Social. Lainey Lui, Melissa Grelo, ...
(Date:12/20/2014)... December 20, 2014 As Risperdal ... forward in U.S. courts, Bernstein Liebhard LLP notes ... that children treated with the medication may experience ... breast development and lactation. The study, which appears ... and adolescents who began treatment with risperidone, an ...
(Date:12/20/2014)... 2014 Xarelto bleeding lawsuits filed ... uncontrollable bleeding and other serious side effects will be ... Louisiana for coordinated pretrial proceedings, Wright & Schulte LLC ... issued an order Friday to transfer 21 Xarelto lawsuits ... federal courts to the Louisiana district court for coordination ...
Breaking Medicine News(10 mins):Health News:CannabisClassifieds.com Maintains its “Craigslist for Cannabis” Standing with Website Re-launch 2Health News:MissyDress: The Prices of Prom Dresses Just Reduced 2Health News:The ladies of The Social urge Canadian women to put themselves first over the holiday season and into the new year in Mediaplanet’s “Women’s Health” campaign 2Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 2Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 3Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 4Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 3Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 4
... The World Health Organization has sounded its concerns about HIV-infected cases ... HIV epidemic’ in Papua, one of the country’s most remote regions. ... an estimated number of 169,000 to 216,000 HIV ... has a head count of 220 million. ,Higher ...
... is under pressure- he is asked to respond to allegations ... Hospital, which ‘cares’ for people with learning and mental disabilities. ... around 100 adults and 17 children, is now under police ... patient sent a letter of complaint to the North and ...
... the spines and skulls of trout causing them to swim in ... U.S. The disease is referred to as ‘whirling disease’. ... cull around 80,000 of the fresh water fish. ,The ... Potomac River's North Branch, which are several miles from both hatcheries. ...
... Researchers have discovered that the same genetic regulator that ... plays a central role in the development of the ... with such gliomas, they showed that knocking out the ... eliminated tumor formation. ,The researchers said their findings ...
... paper authored by two Memorial University faculty members published ... from the Public Library// of// Science (PLoS). Drs. Amin ... of the paper, entitled, "Prevalence of depression among house ... revise the mental health policy." ,Dr. Muhammad ...
... fear has to be dealt with, at least for the ... working for Missouri-Columbia University have come out with disturbing study ... plastics and pesticides. ,Prof Frederick vom Saal, lead ... Advancement of Science, attributed the obesity epidemic sweeping western countries ...
Cached Medicine News:Health News:'Gateway' Gene Discovered for Brain Cancer 2Health News:Be Careful What You Touch, It can Make You Fat 2
(Date:12/19/2014)... Calif. , Dec. 18, 2014  Sage ... new generation of equipment for the testing of ... release of the new Luminary™ Profiler, the industry,s ... light-based measurement in a cost-effective, portable unit. ... the specific needs of the cannabis industry, the ...
(Date:12/19/2014)... 18, 2014 Capnia, Inc. (NASDAQ: ... medical diagnostics based on its proprietary Sensalyze™ Technology ... announced financial results for the third quarter and ... "Following the completion of our initial public offering ... the recently initiated CoSense® commercial launch," said Anish ...
(Date:12/19/2014)... , Dec. 18, 2014 Baptist Health Lexington ... to receive full Atrial Fibrillation with Electrophysiology Services ... (SCPC). Atrial fibrillation is the most common cardiac ... in some cases can lead to stroke and possible death. ... States have atrial fibrillation and the numbers are ...
Breaking Medicine Technology:Sage Analytics Develops Breakthrough System for Potency Testing of Cannabis Products 2Capnia Reports Third Quarter 2014 Financial Results 2Capnia Reports Third Quarter 2014 Financial Results 3Capnia Reports Third Quarter 2014 Financial Results 4Capnia Reports Third Quarter 2014 Financial Results 5Capnia Reports Third Quarter 2014 Financial Results 6Capnia Reports Third Quarter 2014 Financial Results 7Capnia Reports Third Quarter 2014 Financial Results 8Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 2Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 3
... is designed to give accurate and ... neurosurgical intensive care, trauma, and operating ... and easy to use, and provides ... built-in audible alarm alerts attending staff ...
A portable, easy to use, dual-channel laser-Doppler tissue perfusion and temperature monitoring system, at a remarkably affordable price....
... highly featured laser doppler system for ... from multiple tissue sites. This latest ... Signal Processing (DSP) and laser Doppler ... simple to use, multi-channel monitor, setting ...
... highly featured laser doppler system for ... from multiple tissue sites. This latest ... Signal Processing (DSP) and laser Doppler ... simple to use, multi-channel monitor, setting ...
Medicine Products: