Navigation Links
Ingredients in Red Yeast Rice Supplements Vary Widely: Study
Date:10/26/2010

TUESDAY, Oct. 26 (HealthDay News) -- There are widely inconsistent amounts of active ingredient in different formulations of popular red yeast rice supplements, a new study finds. The supplements are marketed as a way to lower cholesterol levels.

In addition, four of the 12 products included in the study had detectable levels of a potentially toxic compound called citrinin, which can damage the kidneys. The toxin is produced by a fungus.

In 2008, Americans spent about $20 million on red yeast rice supplements.

"Several studies have shown that specific formulations of red yeast rice reduce low-density lipoprotein [LDL or 'bad'] cholesterol significantly compared with placebo. This is likely related to the effects of monacolin K and the 13 other monacolins in the supplement, which also works to lower the production of cholesterol in the liver," wrote a team led by Dr. Ram Y. Gordon of Chestnut Hill Hospital in Philadelphia, and Abington Memorial Hospital in Abington, Pa.

In fact, monacolin K is purified and marketed as the cholesterol-lowering drug lovastatin (Mevacor), the researchers noted.

However, according to the study authors, in order to avoid being considered an unapproved drug, manufacturers do not standardize or reveal the levels of monacolin K or other monacolins in their red yeast rice supplements.

Analyses of the 12 products included in this study found that levels of total monacolins ranged from 0.31 milligrams to 11.15 milligrams per capsule, and levels of monacolin K or lovastatin ranged from 0.10 milligrams to just over 10 milligrams per capsule.

"Red yeast rice has been used for centuries for its medicinal properties and is an increasingly popular alternative lipid-lowering therapy that may benefit patients with a history of coronary disease who cannot take statins, subjects who refuse statins or who prefer a 'natural' approach to pharmacotherapy, or patients with a history of statin-associated myalgias [muscle pains]," the researchers wrote.

"However, our study found dramatic variability of monacolin levels in commercial products and the presence of citrinin in one-third of formulations," they added. "Further oversight and standardization of the production and labeling of red yeast rice products may address some of the concerns raised in this study. Until these issues are addressed, physicians should be cautious in recommending red yeast rice to their patients for the treatment of hyperlipidemia [high cholesterol] and primary and secondary prevention of cardiovascular disease."

The study appears in the Oct. 25 issue of the journal Archives of Internal Medicine.

More information

The American Heart Association has more about cholesterol.

-- Robert Preidt

SOURCE: JAMA/Archives news release, Oct. 25, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Shop like Celebrity Chefs at Downtown Santa Monica Farmers' Market. Easy Summer Recipes Incorporate Fresh Ingredients from the Farmers' Market
2. FDA Found Bacteria in Ingredients for Recalled Tylenol, Benadryl
3. Scientific exchange program promotes collaborative quality standards for drugs, food ingredients
4. Best Selling, Non Toxic Skin Brightener Does the Job Using Safe, Healthy Ingredients and Introduces New Anti Aging Ingredients
5. Latest quality and purity specifications for food ingredients help protect consumers
6. Unstable chromosome regions are the origin of yeasts brewing capacity
7. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
8. No Heart Benefit Seen From Folic Acid Supplements
9. Calcium Supplements Linked to Boost in Heart Attack Risk
10. How safe and effective are herbal dietary supplements?
11. New research finds no evidence that popular slimming supplements facilitate weight loss
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Ingredients in Red Yeast Rice Supplements Vary Widely: Study
(Date:6/27/2016)... , ... June 27, 2016 , ... TopConsumerReviews.com recently awarded ... Eyeglasses . , Millions of individuals in the United States and Canada wear ... a way to both correct vision and make a fashion statement. Even celebrities use ...
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media ... give their videos a whole new perspective by using the title layers in ... Studios. , ProSlice Levels contains over 30 Different presets to choose from. ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... , ... The temporary closing of Bruton Memorial Library on June 21 due to a possible ... often overlooked aspect of head lice: the parasite’s ability to live away from a human ... but a necessary one in the event that lice have simply gotten out of control. ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 VolitionRx ... of Dr. Edward Futcher to the ... effective June 23, 2016.Dr. Futcher was also appointed ... Governance Committees.  As a non-executive member of the ... and strategic counsel to VolitionRx in connection with ...
(Date:6/23/2016)... 2016  MedSource announced today that it has ... solution of choice.  This latest decision demonstrates MedSource,s ... their clients by offering a state-of-the-art electronic data ... nowEDC as the EDC platform of choice in ... "nowEDC has long been a preferred EDC platform ...
(Date:6/23/2016)... June 23, 2016 Any dentist who has made ... the current process. Many of them do not even offer ... difficulties and high laboratory costs involved. And those who ARE ... at such a high cost that the majority of today,s ... Dr. Parsa Zadeh , founder of Dental Evolutions Inc. ...
Breaking Medicine Technology: