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Information overload in drug side effect labeling
Date:5/23/2011

treatments for Restless Legs Syndrome and Parkinson's disease. In general, medications typically used by psychiatrists and neurologists had the most complex labels, while drugs used by dermatologists and ophthalmologists had the least.

To conduct this research, the investigators developed computer software capable of identifying side effects in drug labels with 95 percent accuracy. This software, known as SPLICER, can be used to monitor labeling patterns on an ongoing basis and detect changing trends.

"It would take many months of work to read through the 5,600 drug labels and identify all of the side effects. SPLICER can read and process this many labels in about a day on a supercomputer and with nearly the same accuracy as a human. This is especially important since new labels are constantly being created and old ones revised," said co-author Regenstrief Investigator Jeff Friedlin, D.O., assistant professor of family medicine at the IU School of Medicine.

Despite the overwhelming amount of information found in current drug labeling, Dr. Duke remains optimistic.

"With current technology, drug labels could be transformed from lengthy static documents to dynamic resources, capable of delivering personalized patient information. Such labels could take into account the individual patient's medical conditions and highlight those side effects that could be especially dangerous.

"We can't stop the growing wave of drug information," said Dr. Duke, "but we can do a better job of presenting it efficiently to health care providers."


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Contact: Cindy Fox Aisen
caisen@iupui.edu
317-274-7722
Indiana University School of Medicine
Source:Eurekalert  

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