Navigation Links
Inflammatory Bowel Disease Tied to Higher Risk of Post-Op Blood Clots

THURSDAY, Oct. 20 (HealthDay News) -- Researchers report that following surgery, people with inflammatory bowel disease (IBD) may be at increased risk for blood clots known as deep vein thromboses and pulmonary embolisms.

Deep vein thrombosis (DVT) is a blood clot in a deep vein in the thigh or leg -- it's best known as "economy-class syndrome," after cases that occurred in passengers on long-haul flights. DVTs can travel to the lungs and lead to dangerous clots there known as pulmonary embolisms (PE).

"An increased risk of DVT and PE in patients with IBD has been evident for the past 75 years," co-authors Dr. Andrea Merrill of Massachusetts General Hospital and Dr. Frederick Millham of Newton-Wellesley Hospital, both in Boston, wrote in the study published in the Oct. 17 online edition of the journal Archives of Surgery.

However, they added that "most work in this area has not looked specifically at patients undergoing surgery." Because surgery is common for people with IBD, getting a better idea of their level of risk for these clots is important, the researchers said.

According to the American College of Family Physicians, over 600,000 Americans suffer from IBD, which involves a chronic inflammation of the intestines. Crohn's disease and ulcerative colitis are two common forms of IBD.

In their study, Merrill and Millham looked at data from over 2,200 IBD patients and almost 270,000 patients without IBD who had surgery at 211 U.S. hospitals in 2008.

Overall, there were 2,665 cases of DVT or PE (1 percent), but the rate among patients with IBD was more than double, at 2.5 percent.

Interestingly, surgeries in locations away from the intestines had an even higher rate of DVT or PE for people with IBD -- 5 percent, the investigators found.

Rates of post-surgical heart attack or stroke were not different in IBD patients versus those without the illness, the team noted in a journal news release.

The researchers concluded that "patients with IBD who undergo surgery have a twofold increased risk of DVT or PE. In patients with IBD who are having nonintestinal surgery, this risk may be even higher. These findings suggest that standard DVT and PE prophylaxis [prevention] should be reconsidered for this patient group."

One expert said the new finding may have an impact on clinical practice.

"Current guidelines do not recommend routine DVT and PE prophylaxis in patients with IBD undergoing surgery," said Dr. David Bernstein, chief of the division of gastroenterology at North Shore University Hospital in Manhasset, N.Y.

However, he said that "the data presented in this study begs the question that perhaps the approach to prevention of DVT and PE in IBD patients undergoing routine, non-emergent surgery needs to be reassessed."

More information

There's more on inflammatory bowel disease at the American Academy of Family Physicians.

-- Robert Preidt

SOURCES: David Bernstein, M.D., chief, division of gastroenterology, North Shore University Hospital, Manhasset, N.Y.; JAMA/Archives journals, news release, Oct. 17, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New study shows inflammatory food toxins found in high levels in infants
2. Inflammatory mediator enhances plaque formation in Alzheimer’s disease
3. Starving inflammatory immune cells slows damage caused by multiple sclerosis
4. Common anti-inflammatory coaxes liver cancer cells to commit suicide
5. Anti-inflammatory drug may fight breast cancer
6. Sonography complements physical exam in identifying juvenile inflammatory arthritis in children
7. Digestive experts grade treatment options for inflammatory bowel disease
8. Aspirins ability to protect against colorectal cancer may depend on inflammatory pathways
9. Non-steroidal anti-inflammatory drugs linked to increased risk of erectile dysfunction
10. Porphyromonas gingivalis accelerates inflammatory atherosclerosis in a mouse model
11. Link between depression and inflammatory response found in mice
Post Your Comments:
Related Image:
Inflammatory Bowel Disease Tied to Higher Risk of Post-Op Blood Clots
(Date:6/26/2016)... ... ... Quality metrics are proliferating in cancer care, and are derived from many of ... beholder, according to experts who offered insights and commentary in the current issue of ... full issue, click here . , For the American Society of Clinical Oncology ...
(Date:6/26/2016)... Clarkston, Michigan (PRWEB) , ... June 26, 2016 ... ... respect to fertility once they have been diagnosed with endometriosis. These women need ... but they also require a comprehensive approach that can help for preservation of ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the largest ... as the Medical Director of its new Mesquite-Samuell Farm facility. , “We are ... Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency ...
(Date:6/24/2016)... ... , ... A recent article published June 14 on E Online ... on to state that individuals are now more comfortable seeking to undergo not only ... calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced ... attorneys chosen by their peers for this recognition are considered among the top 2 ... received special honors as members of this year’s Legal Elite Hall of Fame: ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Global Blood Therapeutics, Inc. (GBT) (NASDAQ: ... novel therapeutics for the treatment of grievous blood-based ... closing of its previously announced underwritten public offering ... public offering price of $18.75 per share. All ... by GBT. GBT estimates net proceeds from the ...
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical Systems ... "Company"), which develops, markets and sells medical devices and ... , signed a strategic cooperation agreement with Hongyuan Supply ... Supply Chain") on June 20, 2016, to develop Dehaier,s ... strategic cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s ...
(Date:6/24/2016)... Belgium , June 24, 2016 ... today announced the appointment of Dr. Edward ... as a Non-Executive Director, effective June 23, 2016.Dr. ... Compensation and Nominations and Governance Committees.  As a ... will provide independent expertise and strategic counsel to ...
Breaking Medicine Technology: