Navigation Links
Infection contributes to the high rates of oropharyngeal cancers
Date:8/26/2007

Though the overall incidence of head and neck cancers has fallen in the United States, the rate of oropharyngeal (chiefly, tonsil and base of tongue) cancers is stagnant and appears to be rising is certain populations and these trends are likely due to oncogenic human papillomavirus (HPV) infection. A review published in the October 1, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society, finds an increasing trend in the incidence of oropharyngeal cancers, particularly among men under 45 years old, for which HPV infection is the likely cause.

Cancers of the head and neck, which include cancers of the larynx, nasal passages/nose, oral cavity, pharynx, and salivary glands, account for three percent of all newly diagnosed cancers in the U.S. Men are three times more likely to be diagnosed with these cancers than women. Of the estimated 45,000 new cases of head and neck cancers expected this year, approximately 10,000 are cancers of the pharynx (chiefly the oropharynx). Though the prognosis for these cancers is excellent when caught early, more than half of them are identified in advanced stages, when the prognosis is far worse, making prevention critical to saving lives.

In their review, Erich M. Sturgis, M.D., M.P.H. and Paul Cinciripini, Ph.D. of The University of Texas M. D. Anderson Cancer Center in Houston, conclude that the stagnate incidence rates of oropharyngeal cancers, particularly cancers of the tonsil and base of tongue, in the face of declines in tobacco use, the principal cause of head and neck cancers, are likely explained by rising prevalence of oropharyngeal exposure to an oncogenic virus. They say the literature points to exposure to HPV especially strain 16 as having the strongest association to oropharyngeal cancers. However, the authors suggest that a recently approved HPV vaccine may ultimately have a significant impact on the incidence of oropharyngeal tumors.

While the cervical cancer and dysplasia prevention policy of HPV16/18 vaccination of young women and adolescent females are commended, we fear that vaccination programs limited to females will only delay the potential benefit in prevention of HPV16/18 associated oropharyngeal cancers, which typically occur in men, conclude the authors.

The authors encourage the rapid study of the efficacy and safety of these vaccines in males and, if successful, the recommendation of vaccination of young adult and adolescent males.


'/>"/>
Contact: Amy Molnar
amolnar@wiley.com
John Wiley & Sons, Inc.
Source:Eurekalert

Related medicine news :

1. Patients With Filariasis More Prone To HIV Infection
2. Gay capital reeling with rising HIV infection
3. And now they say infections can cause heart disease!!!!
4. And now they say infections can cause heart disease!!!!
5. Tattoos may significantly increase risk of hepatitis C infection
6. Antibiotic induces liver damage in children with E.COLI infections.
7. Ear infection- a new treatment
8. Acne may protect against infections
9. Link Between Ear Infections And Asthma
10. Eliminating Eye Infection With Antibiotics
11. Eliminating Eye Infection With Antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... ... July 19, 2017 , ... Dr. Jig Patel is ... Schaumburg, IL, with or without a referral. Understanding the difficulties that face people who ... when they choose this permanent alternative to removable dentures and bridges. Not only does ...
(Date:7/20/2017)... ... July 19, 2017 , ... Adolfson & Peterson ... manager, Josh Christensen. As a leader in healthcare construction, AP has successfully built ... resume in the Midwest with Josh now on board. , Josh brings ...
(Date:7/20/2017)... (PRWEB) , ... July 20, 2017 , ... “Lucky the Buffalo and Her Adventures”: a ... of published author, Edward Bieniek. Edward Steven Bieniek Jr. was born in Toledo, Ohio. ... of Toledo at com tech. He is married to a brilliant woman with a ...
(Date:7/18/2017)... (PRWEB) , ... July 18, 2017 , ... The results of an international clinical trial, ... drug therapy for a severe type of muscular dystrophy holds promise for a subgroup of ... Craig McDonald and colleagues at 53 study sites in 18 countries describe the ...
(Date:7/18/2017)... (PRWEB) , ... July 18, 2017 , ... Heritage Woods ... from 11 a.m. to 12:30 p.m. on Aug. 15. , The community, which is ... including those on Medicaid, who need some help to maintain their independence. , The ...
Breaking Medicine News(10 mins):
(Date:7/11/2017)... July 11, 2017 Zymo Research Corp., also known as ,The ... quantify biological aging in a precise manner using the myDNAge ™ ... , a professor of human genetics and biostatistics at the David ... Public Health , Zymo Research,s proprietary DNAge ™ technology is used ... ...
(Date:7/11/2017)...  Dr. Echenberg, founder of Echenberg Institute, is announcing a new safe ... from painful intercourse and other painful pelvic pain conditions such as pelvic ... ... ... Florida -based start-up company, VuVatech LLC, fills a void in the ...
(Date:7/10/2017)... 10, 2017  BDI Group subsidiary Pathway Purchasing ... services organization serving specialty pharmacies, home infusion companies ... four significant, value-added member programs designed to help ... reimbursement and improve access and affordability for patients ... Pathway has ...
Breaking Medicine Technology: