Navigation Links
Infant pain, adult repercussions
Date:9/25/2009

ATLANTA Scientists at Georgia State University have uncovered the mechanisms of how pain in infancy alters how the brain processes pain in adulthood.

Research is now indicating that infants who spent time in the neonatal intensive care unit (NICU) show altered pain sensitivity in adolescence. These results have profound implications and highlight the need for pre-emptive and post-operative pain medicine for newborn infants.

The study, published online in the journal Frontiers in Behavioral Neuroscience, sheds light on how the mechanisms of pain are altered after infant injury in a region of the brain called the periaqueductal gray, which is involved in the perception of pain.

Using Sprague-Dawley rats, Jamie LaPrairie, a graduate student in associate professor Anne Murphy's laboratory, examined why the brief experience of pain at the time of birth permanently decreased pain sensitivity in adulthood.

Endogenous opioid peptides, such as beta-endorphin and enkephalin, function to inhibit pain. They're also the 'feel good' substances that are released following high levels of exercise or love. Since these peptides are released following injury and act like morphine to dampen the experience of pain, LaPrairie and Murphy tested to see if the rats, who were injured at birth, had unusually high levels of endogenous opioids in adulthood.

To test this hypothesis, LaPrairie and Murphy gave adult animals that were injured at the time of birth a drug called naloxone. This drug blocks the actions of endogenous opioids. After animals received an injection of naloxone, they behaved just like an uninjured animal.

The scientists then focused on the periaqueductal gray region to see if inflammation at birth altered the natural opioid protein expression in this brain region. Using a variety of anatomical techniques, the investigators showed that animals that were injured at birth had endogenous opioid levels that wer
'/>"/>

Contact: Jeremy Craig
jcraig@gsu.edu
404-413-1357
Georgia State University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Nicotine in breast milk disrupts infants sleep patterns
2. Shaking may cause brain damage and serious long-term effects to infants
3. Maternal depression and controlling behavior associated with increased stress response in infants
4. Repeat steroids to premature infants linked to cerebral palsy
5. Babies raised in bilingual homes learn new words differently than infants learning one language
6. Joint Center Says New Approach Required to Reduce Black Infant Mortality
7. After Infant Gripe Water Recall Scare, Homeopathic Medicine Offers Safe Alternative
8. Vaginal progesterone gel may improve infant outcomes and...
9. Research shows how genetic mutation causes epilepsy in infants
10. Combination vaccines okay for infants, study shows
11. New York Citys infant mortality rate declined in 2006
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... 2014 Patients suffering from vitiligo can ... a new review published by Daily Gossip. , ... so there is no wonder that numerous sufferers search ... Vitiligo Treatment is one of the most appreciated such ... promises to stop the spread of this disorder immediately, ...
(Date:8/30/2014)... 30, 2014 The Plastic Surgery Group ... Jersey and even in the U.S. to provide clients ... off of patients’ waists with deep-tissue heating. , Unlike ... sections, Vanquish is more inclusive to target large sections ... comfortably under panels about one inch away from their ...
(Date:8/30/2014)... 30, 2014 The establishment and ... has been one of the main strategies of ... a positive impact around the world. , Architecturally ... top trained executives and trainers deliver L. Ron ... Vital statistics demonstrate that significant reduction in ...
(Date:8/30/2014)... Richmond, VA (PRWEB) August 30, 2014 Seniors ... several articles recently that focus on Alzheimer’s Disease, Dementia, ... recently revealed to the public of being diagnosed with the ... his latest movie, “I’ll Be Me”. The movie, out ... life while focusing on his diagnosis of the disease – ...
(Date:8/30/2014)... Randy Dotinga HealthDay ... About one in five patients operated on for broken bones ... surgery, a new study finds. Less-educated patients and ... more likely to be "doctor shoppers," said study lead author ... Ky. Overall, he said, the study suggests that doctors aren,t ...
Breaking Medicine News(10 mins):Health News:Natural Vitiligo Treatment Review Exposes Fast Method for Skin Repigmentation 2Health News:NJ Top Docs Presents, The Plastic Surgery Group 2Health News:Cradle of Aviation Museum Opens Its Doors to Long Island Scientologists 2Health News:Alzheimer’s Disease and Dementia Focus on Retirement Website SeniorsGuideOnline.com 2Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 2Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 3
... 6 Prescription pediatric drugs represent,an enormous market, with ... growth is forecast at a modest 3.2%, reaching $43,billion ... share of 11.7%, is,expected to achieve the highest growth ... Kalorama Information,s new report The World Market for,Pediatric Drugs., ...
... Medical Solutions, Inc.,(Rising), a leading medical cost ... Index (PCI) "Top Growth Company" list for ... http://www.newscom.com/cgi-bin/prnh/20080206/AQW030LOGO-b ), (Logo: http://www.newscom.com/cgi-bin/prnh/20080206/AQW030-a ... Inc. ( http://www.entrex.net ), is a,proprietary benchmarking ...
... restatement of Beth Israel Deaconess,Medical Center audit, ... apply the same Sarbanes-Oxley standards used by Massbank ... the board of Beth Israel,Deaconess Medical Center (BIDMC), ... East. Bufferd is also the retired treasurer of,Massachusetts ...
... The Female Health Company,(Amex: FHC ) ... conference call,to discuss its operating results for the ... (EST) on Wednesday, February 13, 2008. The Company ... earlier the same day., Shareholders and other ...
... Medical cost increases for,employers throughout the world ... according to a poll of insurance companies conducted ... The poll also found,that, in a vast majority ... rate of inflation., Nearly three-fourths (71 percent) ...
... A new statewide survey,released today shows that ... tax revenue for programs to prevent kids,from starting ... poll of 500 Virginia voters was released today ... Lung Association and,the Campaign for Tobacco-Free Kids. The ...
Cached Medicine News:Health News:Diabetes, Growth Disorders Drive Sales of Pediatric Hormone Drugs 2Health News:Rising Medical Solutions, Inc. Ranks Fifth on the Private Company Index (PCI) 'Top Growth Companies' List 2Health News:Massbank Board Member Should Use Sarbanes-Oxley Disclosure Rules in Non-Profit Role, Asserts 1199 SEIU 2Health News:The Female Health Company Schedules First Quarter Conference Call for February 13, 2008 2Health News:Medical Cost Increases to Accelerate Worldwide Over Next Five Years, Watson Wyatt Poll Finds 2Health News:Medical Cost Increases to Accelerate Worldwide Over Next Five Years, Watson Wyatt Poll Finds 3Health News:New Poll Shows Virginia Voters Overwhelmingly Favor Funding for Tobacco Prevention 2Health News:New Poll Shows Virginia Voters Overwhelmingly Favor Funding for Tobacco Prevention 3
(Date:8/29/2014)... , Aug. 29, 2014 Research and ... Disorders Drug Pipeline Insight 2014" report to their offering. ... in US is one of the largest segments of pharmaceuticals ... alarming rate, while the available therapies were unable to meet ... in the market for CNS disorder, especially over the past ...
(Date:8/29/2014)... Research and Markets has announced the addition ... Pharmaceutical Equipment Market in China, 2014-2018" report to ... Forecast of Pharmaceutical Equipment Market in China ... pharmaceutical equipment industry in the aspects of current ... performance of domestic major enterprises, as well as offers ...
(Date:8/29/2014)... According to the new ... (Equipment, Reagent, Primer, Probe, Custom Oligos), End-User (Research, ... Synthesis, NGS, DNA, RNAi) - Global Forecast to ... Market is expected to reach $1,712.1 Million by ... a CAGR of 9.8% from 2014 to 2019.. ...
Breaking Medicine Technology:US CNS Disorders Drug Pipeline Insight 2014 2Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 3Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 4
... Adeona Pharmaceuticals, Inc. (NYSE Amex: AEN ... nervous system diseases, announced today that it received a ... an honoree, the Company is highlighted in the magazine,s ... is available via the "Adeona in the News" section ...
... Hospitals using interactive technology to communicate with ... and increased satisfaction with hospital educational materials and ... a white paper released by The Beryl ... ) The publication examines how interactive ...
Cached Medicine Technology:Patient Satisfaction and Patient Education Increase When Hospitals Offer Interactive Technology 2Patient Satisfaction and Patient Education Increase When Hospitals Offer Interactive Technology 3
1000 L, Racked, Pre-sterilized, 100 tips/rack Recommended for 500 and 1000 L pipettes....
300 L, Racked, Filtered, Pre-sterilized, 96 tips/rack Recommended for 250 and 300 L pipettes....
Diamond Filter Tips play a critical role in preventing aerosol-borne contamination. Also available sterilized (no need to autoclave) and certified free of detectable RNase, DNase, DNA, RNA, and prote...
... Eliminate aerosol contamination, which ... in PCR. Hydrophobic, nonwicking ... air can pass through ... in contrast to tips ...
Medicine Products: