Navigation Links
Induction of adult cortical neurogenesis by an antidepressant
Date:1/4/2013

The production of new neurons in the adult normal cortex in response to the antidepressant, fluoxetine, is reported in a study published online this week in Neuropsychopharmacology.

The research team, which is based at the Institute for Comprehensive Medical Science, Fujita Health University, Aichi, has previously demonstrated that neural progenitor cells exist at the surface of the adult cortex, and, moreover, that ischemia enhances the generation of new inhibitory neurons from these neural progenitor cells. These cells were accordingly named "Layer 1 Inhibitory Neuron Progenitor cells" (L1-INP). However, until now it was not known whether L1-INP-related neurogenesis could be induced in the normal adult cortex.

Tsuyoshi Miyakawa, Koji Ohira, and their colleagues employed fluoxetine, a selective serotonin reuptake inhibitor, and one of the most widely used antidepressants, to stimulate the production of new neurons from L1-INP cells. A large percentage of these newly generated neurons were inhibitory GABAergic interneurons, and their generation coincided with a reduction in apoptotic cell death following ischemia. This finding highlights the potential neuroprotective response induced by this antidepressant drug. It also lends further support to the postulation that induction of adult neurogenesis in cortex is a relevant prevention/treatment option for neurodegenerative diseases and psychiatric disorders.


'/>"/>

Contact: Tsuyoshi Miyakawa
miyakawa@fujita-hu.ac.jp
81-562-939-375
National Institute for Physiological Sciences
Source:Eurekalert

Page: 1

Related medicine news :

1. Chemotherapy proves life-saving for some leukemia patients who fail induction therapy
2. Impact of caring for adult child with disability studied
3. Rosacea Treatment Concealer Cream Released for Adults by Revitol
4. Texas Clinic Now Accepting Brachial Plexus Patients; Children and Adults
5. Many Adults With Autism Unhappy With Their Health Care
6. Adult Tricycles Designed by Freedom Concepts Now Offered by Rehabmart.com
7. Fear of falling may cause social isolation in older adults with vision problems
8. Adult Toys Make Perfect Gifts for Your Partner This Holiday Season According to Condomania.com
9. Autistic adults report significant shortcomings in their health care
10. RI Hospital: Standardized road test results differ from older adults natural driving
11. Adult antiviral drug effective in suppressing hepatitis B in teens
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... With the accelerated aging of the ... as well as the improved medical care facilities ... industry has been developing quickly, especially in vitro ... in vitro diagnostics market size reached RMB22.98 billion, ... diagnostic reagents. , Chinese in vitro diagnostic ...
(Date:7/30/2014)... Angeles, California (PRWEB) July 30, 2014 ... an online dating community where motorcycle enthusiasts congregate, ... on the site that were revealed by BikerKiss indicate ... increase in the past 3 years. , Members on ... US, UK, Canada, Australia and some other European countries ...
(Date:7/30/2014)... WA (PRWEB) July 30, 2014 According to ... Vkool.com, this is a comprehensive bodybuilding guide for men who ... by up to 50 pounds in within a few ... that will help keep their shoulders healthy and avoid the ... the Critical Bench Program 2.0 uncovers to learners the reason ...
(Date:7/30/2014)... San Diego, CA (PRWEB) July 30, 2014 ... of Melinda J. Helbock A.P.C. are announcing that they are ... from the negative effects of asbestos exposure. , “Symptoms ... that were exposed to the toxin 30 plus years ago ... Melinda Helbock, Founder of The Law Office of Melinda J. ...
(Date:7/30/2014)... TN (PRWEB) July 30, 2014 Regents ... medical imaging services, has brought health care industry veteran ... on board to help lead the company’s ambitious plans ... , “Regents Health has been moving along at a ... to kick it up a notch,” says Bob Maier, ...
Breaking Medicine News(10 mins):Health News:China Diagnostic Reagent Industry (biochemical, molecular & immunodiagnostic) 2016 Forecasts in New Research Report at ChinaMarketResearchReports.com 2Health News:China Diagnostic Reagent Industry (biochemical, molecular & immunodiagnostic) 2016 Forecasts in New Research Report at ChinaMarketResearchReports.com 3Health News:China Diagnostic Reagent Industry (biochemical, molecular & immunodiagnostic) 2016 Forecasts in New Research Report at ChinaMarketResearchReports.com 4Health News:Single Women Motorcycle Riders In Rapid Increase 2Health News:The Critical Bench Program 2.0 Pdf Review Exposes Mike Westerdal's Guide for Increasing Bench Press – Vkool.com 2Health News:The Critical Bench Program 2.0 Pdf Review Exposes Mike Westerdal's Guide for Increasing Bench Press – Vkool.com 3Health News:The Law Office of Melinda J. Helbock A.P.C. Offers Case Evaluations for Possible Asbestos Claims 2Health News:Sferrella and Demonbreun Join Regents Health Resources 2
... the long-term consequences of too much sun exposure can be ... anyone who's spent a day basking on the beach. ,Characterized ... to the touch, sunburn is a sure, almost immediate sign ... been damaged by the sun's ultraviolet rays. And the consequences ...
... havoc on a woman’s bones and a new study reveals ... Researchers know bone loss occurs after menopause, increasing chances of ... and strength. ,The Swedish study involved 146 women who were ... done to determine bone size and density. //All fractures related ...
... week may cut their risk of Alzheimer's by more than ... that diet may affect a person's chances of developing the ... that people 65 and older who had fish once a ... those who never or rarely ate fish. The meals included ...
... you don't use your mind regularly through activities such ... you risk losing some of your cognitive abilities as ... appearing in the June 19 issue of the New ... of Medicine in New York City found seniors who ...
... Clinic in Rochester, Minn., say they have found a ... is an allergic inflammatory reaction of the esophagus. The ... research shows a topical corticosteroid therapy is effective for ... of high levels of eosinophils. Eosinophils are a type ...
... women with colon cancer that has advanced beyond the ... outcome, according to a recent study. In addition to ... may have an increased risk of cancer recurrence, at ... long-term outcomes and treatment-related side effects in colon cancer ...
Cached Medicine News:
(Date:7/29/2014)... July 29, 2014 New high priced hepatitis ... D by a projected $2.9 to $5.8 billion next ... firm Milliman released today by the Pharmaceutical Care Management ... could increase by as much as 8.6 percent in ... including Sovaldi and Olysio. The study finds ...
(Date:7/29/2014)... July, 29  2014 ISPE—the International Society for ... John Bournas as President and CEO, succeeding ... leave the Society last fall.  Mr. Bournas takes ... the healthcare association industry as well as significant ... clear vision for the expansion of its global ...
(Date:7/29/2014)... July 29, 2014 /PRNewswire-iReach/ -- MHG Medical Management ... launched its Medical Equipment and X-ray Annual ... are tailored to the cruise industry,s unique requirements.  ... operators to propose that they should develop a ... program is intended to create standardized processes and ...
Breaking Medicine Technology:New Milliman Study: Hepatitis C Drugs Could Increase Medicare Part D Spending by $2.9 to $5.8 Billion in 2015 2ISPE Hires Healthcare Association Exec as CEO 2ISPE Hires Healthcare Association Exec as CEO 3MHG Medical Management Services Aims to Change Cruise Industry Standard With New Equipment Maintenance Program 2
... (NYSE: WPI ), a leading specialty global ... and Chief Executive Officer, will provide an overview and ... Bernstein 28th Annual Strategic Decisions Conference on Wednesday, May ... Hotel in New York, New York.  The presentation will ...
...  Perrigo Company (Nasdaq: PRGO;TASE) today announced that it has ... Administration for its abbreviated new drug application (ANDA) for ... have already begun.  (Logo: http://photos.prnewswire.com/prnh/20120301/DE62255LOGO ... U.S. store brand market is bioequivalent to Novartis, Prevacid® ...
Cached Medicine Technology:Watson to Present at the Sanford C. Bernstein 28th Annual Strategic Decisions Conference 2Perrigo Announces FDA Final Approval and Launch of Store Brand OTC Lansoprazole 15mg Capsules 2
Molt periosteal elevator #9, 18.5 cm, 7-1/4"....
Periosteal elevator #9, 18 cm, 7"....
Full curve periosteal elevator - cervical - sharp, round tip, length 184 mm (7 1/4")....
... The Frontier Anterior Deformity System ... Kass, Moss Miami, and Isola ... thoracoscopic procedures to deliver unsurpassed versatility, ... the highest level of versatility for ...
Medicine Products: