Navigation Links
Indiana University to host national biorepository for gene therapy
Date:6/19/2008

INDIANAPOLIS Indiana University School of Medicine will be home to the nation's sole National Gene Vector Biorepository and Coordinating Center (NGVB) for gene therapy research with a three-year, $3 million grant from the National Institutes of Health.

The program is directed by Kenneth Cornetta, M.D, Joe C. Christian Professor and chair of Medical and Molecular Genetics and professor of medicine and of microbiology and immunology. The three year grant to the School of Medicine was effective June 15.

"This center will continue the IU School of Medicine's history of providing critical resources to gene therapy researchers, who are working to find treatments for some of our most difficult diseases," said Dr. Cornetta.

Researchers use gene vectors, such as disabled viruses, to carry genetic materials in the body in hopes of treating or preventing disease. For example, genes important for fighting infections may be inserted into immune system cells that have been rendered inactive by genetic mutations.

The NGVB at Indiana University will help university scientists share research information and substances to promote discoveries, patient safety and compliance with regulations of the Food and Drug Administration. The NGVB's services will include maintaining a warehouse of important reagents, disseminating the results of safety studies, and the storage of biological materials and patient specimens in accordance with FDA regulations. The IU center will also conduct studies of the safety of various gene therapy techniques, said Dr. Cornetta.

"The new biorepository and center will help leverage information-sharing and expertise across the gene therapy research community," said Barbara M. Alving, M.D., director of the National Center for Research Resources, the NIH center that is funding the grant. "By coordinating preclinical studies, this resource will maximize NIH's investment in gene vector research and help translate new knowledge into tangible benefits for patients."

Scientists are using gene transfer techniques in studies involving a broad range of diseases including cancer, heart disease, cystic fibrosis, immune disorders including arthritis, and infectious diseases. An NIH database lists more than 500 such trials currently under way.

The NGVB replaces the National Gene Vector Laboratory and Coordinating Center at the IU School of Medicine, which provided gene therapy vectors for use in clinical trials. Indiana University continues to provide gene therapy vectors under contracts with the National Cancer Institute and the National Heart Lung and Blood Institute.


'/>"/>

Contact: Eric Schoch
eschoch@iupui.edu
317-274-7722
Indiana University
Source:Eurekalert

Related medicine news :

1. The role of giving explored by Indiana University physician-author
2. HHS Takes Action to Help Medicare Beneficiaries and Providers in Iowa and Indiana
3. Camp Bow Wow(R) Launches Fundraising Effort to Help Cure Cancer in Dogs, via Morris Animal Foundations Canine Cancer Campaign - Dogs Get Bandanas; Camp Bow Wow in Indianapolis is Participating
4. AARP Indiana Key Vote News Alert: AARP Dismayed by Senate Vote to Block Medicare Improvement Bill
5. National Pharmaceutical Company to Sponsor Popular Indianapolis Walk
6. Lilly to Provide Aid to Indiana Tornado and Flood Victims
7. Publicis Indianapolis and St. Vincent Hospital Win the Gold
8. Indiana University research at the American College of Sports Medicine annual conference
9. NIH awards $25M clinical research grant to Indiana U for statewide initiative
10. Hear Indiana Announces Talk*Walk*Run 2008
11. Skanska Opens Indianapolis Office
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating ... many ways they remain in the eye of the beholder, according to experts who ... of The American Journal of Managed Care. For the full issue, click here ...
(Date:6/26/2016)... Orion, Clarkston, Michigan (PRWEB) , ... June 26, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse but they also require a comprehensive approach that can help for preservation ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... are unfamiliar with. The article goes on to state that individuals are now more ... these less common operations such as calf and cheek reduction. The Los Angeles area ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced ... attorneys chosen by their peers for this recognition are considered among the top 2 ... received special honors as members of this year’s Legal Elite Hall of Fame: ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... Market by Type (Standard Pen Needles, Safety Pen Needles), ... (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, Non-Retail) ... MarketsandMarkets, This report studies the market for the forecast ... to reach USD 2.81 Billion by 2021 from USD ...
(Date:6/23/2016)... , June 23, 2016  MedSource announced ... as its e-clinical software solution of choice.  This ... best possible value to their clients by offering ... The preferred relationship establishes nowEDC as the EDC ... for MedSource,s full-service clients.  "nowEDC has long been ...
(Date:6/23/2016)... a startling report released today, National Safety Council research ... proven plan to eliminate prescription opioid overdoses. Prescription Nation ... tackling the worst drug crisis in recorded U.S. history, assigned a ... , New Mexico , Tennessee ... failing states, three – Michigan , ...
Breaking Medicine Technology: