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Indiana U medical researchers boost research and jobs with stimulus legislation grants
Date:9/15/2009

men Yoder, Ph.D., assistant professor of radiology, who will be able to hire a new research assistant for the project. She will be using PET scanning techniques to evaluate dopamine a neurotransmitter known to be involved with cognition and implicated in pain in fibromyalgia patients, who complain of both severe pain and problems in thinking clearly.

"A lot of fibromyalgia patients are heavily medicated with addictive pain killers and they still don't get much relief," said Dr. Yoder. "If we understand the central mechanisms of pain in the brain, we can develop better therapeutic strategies for pain."

A $20,328 grant enabled Richard N. Day, Ph.D., professor of cellular and integrative physiology, to hire an undergraduate research assistant for this summer and next, which he said has speeded up his lab's research into mutations of a particular protein in the pituitary gland that blocks the production of important hormones, including growth hormone.

Laura Whitis, the IUPUI biology major working in the lab, said her goal is to do research and find effective treatments for genetic disorders.

A grant of nearly $419,000 will enable Reuben Kapur, Ph.D., associate professor of pediatrics, to continue studying how vital cells in the bone marrow called hematopoietic stem cells renew themselves. These adult stem cells are responsible for the creation of all the body's red and white blood cells and are the key component in bone marrow and cord blood transplants used to treat leukemia, lymphomas and other diseases. In particular, Kapur and his team will evaluate a compound that could make it easier to grow the cells in the laboratory, which could improve the availability and effectiveness of the cord blood and bone marrow transplants.

Without the grant, Dr. Kapur said, it would have been necessary to reduce his laboratory staff by three full time positions, including two post-doctoral researchers and a laboratory technician.


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Contact: Eric Schoch
eschoch@iupui.edu
317-274-7722
Indiana University
Source:Eurekalert

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