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Indiana U medical researchers boost research and jobs with stimulus legislation grants
Date:9/15/2009

leagues challenges the traditional view that proteins' three dimensional structures are key to determining their function. They have identified many proteins that perform crucial tasks without specific structures and in the process are opening new potential avenues to treat such diseases as cancer, heart disease, diabetes, Parkinson's, Alzheimer's, and others.

With a $1.5 million grant from the National Institutes of Health a team of scientists will investigate how the vaccinia virus, which is related to the smallpox virus, alters the function of immune cells to avoid being detected by the body's immune system. Vaccinia is the virus used to create vaccines against smallpox infection, and improving the vaccine capabilities of this virus will be useful in preventing smallpox infection as well as in the design of new vaccines against cancer and other infectious diseases. The research team includes Janice Blum, Ph.D., Chancellor's Professor and professor of microbiology and immunology, Randy Brutkiewicz, Ph.D., professor of microbiology and immunology, Mark Kaplan, Ph.D., professor of pediatrics and David Wilkes, M.D., August M. Watanabe Professor of Medical Research, and professor of microbiology and immunology. The grant will create at least six new research positions and retain the jobs of three more.

"These awards not only are supporting science that will translate into better health and a stronger economy for Hoosiers, but are creating, and saving, many important laboratory research jobs," said D. Craig Brater, M.D., Walter J. Daly Professor and dean of the IU School of Medicine.

"The high level at which our scientists are conducting research is demonstrated by these awards, which will benefit people across Indiana and beyond," said Dr. Wilkes, executive associate dean for research affairs at the school of medicine.

Additional examples of the projects follow:

Fibromyalgia is the subject of a $237,000 award to Kar
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Contact: Eric Schoch
eschoch@iupui.edu
317-274-7722
Indiana University
Source:Eurekalert

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