Navigation Links
Increasing access to antiretroviral drugs would drastically cut AIDS deaths in South Africa

More that 1.2 million deaths could be prevented in South Africa over the next five years by accelerating efforts to provide access to antiretroviral therapy (ART), according to a study released online today by the Journal of Infectious Diseases. Using a sophisticated mathematical model of HIV disease and treatment, a team of researchers led by Rochelle Walensky, MD, MPH of Massachusetts General Hospital (MGH) estimated the number of AIDS-related deaths in South Africa through 2012 under alternative ART scale-up assumptions.

The study results underscore the urgent need for Congress to reauthorize the U.S. Presidents Emergency Plan for AIDS Relief (PEPFAR), which has supported the South African governments effort to increase access to antiretroviral therapy, the researchers note. If ART is not provided to all who need it, HIV mortality will be enormous, says Walensky. Deliberate, purposeful, and expedient scale-up will save millions of lives in South Africa alone.

South Africa has one of the largest burdens of HIV infection in the world, with 5 to 6 million individuals and 19 percent of adults aged 15 to 49 infected. While government programs supported by PEPFAR and the Global Fund to Fight AIDS, Tuberculosis and Malaria have steadily increased access to antiretrovirals, at the end of 2006 only a third of individuals eligible for the therapy were receiving it.

In order to quantify the potential impact of various strategies for increasing access to ART, the research team projected the number of deaths under five scenarios ranging from maintaining current access levels, through steady and moderate growth levels, to rapid growth and full access for all patients requiring treatment. Among other factors, calculations were based on the fact that the one-year survival rate for eligible patients who receive antiretroviral therapy is 94 percent, while only 55 percent of those not treated would be expected to survive one year.

Results showed that maintaining current treatment capacity would lead to 2.4 million AIDS-related deaths by 2012. Rapid scale-up, whereby everyone in need would have access by 2011, would reduce the projected number of deaths to 1.2 million during that time period, and immediate full access for all eligible patients would drop deaths to 800,000.

The researchers note that efforts to scale up treatment have resulted in a fivefold increase in access to ART in low and moderate-income countries. Continued investments in antiretroviral treatment programs worldwide are a public health imperative; the potential loss of life without such support is simply unacceptable, says Walensky, who is an associate professor of Medicine at Harvard Medical School.


Contact: Sue McGreevey
Massachusetts General Hospital

Related medicine news :

1. Alimera Sciences Closes $30 Million in Series C Financing, Increasing Stake in Medidur(TM) FA
2. Although Remicade and Humira Are Being Increasingly Prescribed for Crohns Disease and Ulcerative Colitis, Insurers Are Subjecting Both Drugs to Multiple Cost-Control Strategies
3. Nanoemulsion vaccines show increasing promise
4. Small-Diameter Dental Implants Increasingly Popular In the US
5. AMA Foundation Honors Memphis, Tennessee Physician for Increasing Access to Health Care in the U.S.
6. AMA Foundation Honors Canton, Ohio Physician for Increasing Access to Health Care in the U.S.
7. AMA Foundation Honors Atlanta Physician for Increasing Access to Health Care in the U.S.
8. Congenital heart defects increasing among IVF twins
9. Workplace opportunities and stresses are both increasing
10. Generic Prescription Drugs Show Increasingly Greater Use in Southeastern Pennsylvania
11. Kidney Disease Increasing in U.S.
Post Your Comments:
(Date:11/29/2015)... ... November 30, 2015 , ... Gift ... company, Sublime Beauty NATURALS®. All products are available on Amazon or its webstore. ... organic facial serums and USDA Certified Organic Sesame Oil for Oil Pulling," says ...
(Date:11/29/2015)... ... 2015 , ... NewsWatch featured X-wing as part of its monthly Tech Report, ... technology expert and special reporter for NewsWatch, conducted the review and shared with viewers ... the future because flying cars are about to become a reality. Where’s the idea ...
(Date:11/29/2015)... ... November 29, 2015 , ... ProStatic Analog Distortion from ... designed specially for Final Cut Pro X. FCPX users can now ... modification controls. Destoying and creating chaotic distortion is now quick and simple, putting ...
(Date:11/28/2015)... (PRWEB) , ... November 28, 2015 , ... Safe storage ... creativity of two inventors, one from Lakewood, New Jersey and the other from Bradley ... the patent-pending PROTECTOR to save the expense of having to replace NuvaRings more often ...
(Date:11/27/2015)... ... November 28, 2015 , ... There is only one major question facing all ... year? , This question has not been an easy question to answer. Especially when ... and the younger workforce don’t share the same discipline around working long hours. ...
Breaking Medicine News(10 mins):
(Date:11/29/2015)... -- The GE Health Cloud 1 was unveiled today at ... North America (RSNA) meeting in Chicago ... cloud ecosystem and its applications will connect radiologists and clinicians ... teams – both inside and outside the hospital setting. ... "As the digital industrial leader, we are betting big on ...
(Date:11/27/2015)... Une nouvelle approche consistant ... contre le cancer avancé.    --> ... au traitement photodynamique au Bremachlorin contre le cancer ... nouvelle approche consistant à combiner l,immunothérapie au traitement ...    Clinical Cancer Research . ...
(Date:11/27/2015)... , Nov. 27, 2015  Lannett Company, ... it has completed the acquisition of Kremers Urban ... subsidiary of global biopharmaceuticals company UCB S.A. (Euronext: ... Lannett has acquired KU from UCB for ... certain adjustments, including a customary working capital adjustment, ...
Breaking Medicine Technology: