Navigation Links
Increased screening may better predict those at higher risk for heart disease, researchers report
Date:5/26/2008

DALLAS May 26, 2008 Adding noninvasive imaging to current risk-assessment protocols may identify more people who are at risk of developing heart disease, UT Southwestern Medical Center researchers have found.

Researchers used data from the UT Southwestern-led Dallas Heart Study to determine whether using computed tomography (CT) to scan patients hearts for calcium deposits and blockages could identify more people at high risk for heart disease and who could benefit from cholesterol-lowering therapy.

The recommendations by the Screening for Heart Attack Prevention and Education (SHAPE) task force are a proposed update to the current guidelines, were updated by the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) in 2004.

In findings published in todays edition of Archives of Internal Medicine, researchers found that the additional imaging proposed by the SHAPE task force did indeed increase the number of patients classified at high risk.

We added imaging of coronary artery calcium, as recommended by the SHAPE task force, to determine if this strategy would augment current risk assessment, said Dr. Jason Lindsey, an author of the paper and cardiology fellow at UT Southwestern.

The efficiency of calcium screening according to the SHAPE recommendations was determined by the number of people who had to be scanned before a single participant was reclassified as either meeting or not meeting individual cholesterol goals.

In our sample of participants in the Dallas Heart Study, we found that by applying SHAPE recommendations compared with the current guidelines (NCEP-ATP III) there was a 27 percent relative increase in the proportion of patients who would need lipid-lowering therapy, said Dr. James de Lemos, associate professor of internal medicine at UT Southwestern and the studys senior author.

SHAPE calls for a broader application of atherosclerosis imaging than is currently recommended. Whether increased imaging of patients will be cost effective in the long term remains to be seen, Dr. de Lemos said.

We cant say what would happen in terms of clinical outcomes, but in terms of risk assessment we can provide a model of how these guidelines would impact treatment, Dr. de Lemos said. We found that for every seven people who had calcium imaging, one needed to readjust cholesterol goals to lower levels.

Coronary calcium scans use computerized tomography (CT) to scan the heart and look for calcium deposits and blockages. The risk of coronary heart disease increases with higher calcium scores.

Calcium buildup can lead to atherosclerosis, a metabolic and inflammatory disease that causes plaque to accumulate in the arteries.

Dr. Scott Grundy, director of the Center for Human Nutrition at UT Southwestern and an author on the Archives paper, served as chairman of the NCEP panel which updated the guidelines for the clinical use of cholesterol-lowering medications to reduce the risk of cardiovascular disease.

Current NCEP guidelines identify three categories of risk based on a person's likelihood to develop cardiovascular disease (heart attack and stroke) in the near future: high risk, moderately high risk, and lower to moderate risk. High-risk individuals are those who have already had a heart attack; cardiac chest pain (angina); previous angioplasty or bypass surgery; obstructed blood vessels to the arms, legs or brain; diabetes; or a collection of other risk factors that raise the likelihood of having a heart attack in the next 10 years by more than 20 percent.

The proportion of participants identified as not meeting their cholesterol goals increased with age, with the greatest net increase among people ages 55 to 65 years old.


'/>"/>

Contact: Katherine Morales
katherine.morales@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert  

Related medicine news :

1. Cumulative radiation exposure shows increased cancer risk for emergency department patients
2. Men at increased risk of death from pneumonia compared to women
3. Somanetics Announces Share Repurchase Program Increased by $15 Million
4. TGrid 5.0 Advances Automatic, High-Quality Meshing Tools for Increased Productivity
5. PPO Industry Calls for Increased Collaboration Among Non-Traditional Allies
6. Obese patients face increased risks for infection and dislocation following revision hip surgery
7. Obesity linked to increased risk for dementia
8. Catholic Charities Calls for Increased Support of Mothers in Need:
9. Garmin Reports Record First Quarter; Strong Margins and Increased Market Share
10. Study Shows Increased Out-of-Pocket Expenses May Negatively Influence Initiation of TNF Blocker Therapy
11. Low Vitamin D Levels Associated With an Increased Risk of Peripheral Arterial Disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Increased screening may better predict those at higher risk for heart disease, researchers report
(Date:1/20/2017)... ... January 20, 2017 , ... Vitamin Well has launched two ... drinks have been produced in collaboration with Zlatan Ibrahimovic and have been developed ... After a successful launch in Sweden last year, the next generation sports drinks ...
(Date:1/20/2017)... ... ... Angel”: a heartwarming and earnest tale of faith and believing in the path ... the creation of published author, Marjorie Lund-Fontaine, a former professional violinist, alumnus of The ... of her new book, Marjorie says, “‘The Angel’ was written as a fairytale, but ...
(Date:1/20/2017)... ... 2017 , ... “I Forgive You”: a fine examination of how God handles sin, including ... of published author, Stephen Miller, who, for over ten long years has been waiting to ... in Trinidad and Tobago, he has been serving the Lord for over twenty years, and ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... “Christmas in ... creation of published author, Sara Seymour, who lives in Lafayette, Indiana where she works ... sips on iced coffees and writes. , Published by Christian Faith Publishing, Sara Seymour’s ...
(Date:1/20/2017)... ... January 20, 2017 , ... “Knowledge is God’s Lighthouse”: a moving and ... God’s Lighthouse” is the creation of published author, Gene Gaapf, a retired truck driver, ... , “I have been writing since high school and have many different titles,” Gaapf ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... 2017 Research and Markets has announced ... Opportunities, and Future" report to their offering. ... This research service on the ... technologies, and provides a snapshot of the key participants in the ... are provided from 2016 to 2020. The market is expected to ...
(Date:1/20/2017)... -- Avillion LLP, a co-developer and financier of late-stage ... MD MBA as Chief Medical Officer. Dr Weinberg will be based ... ... spent more than 17 years as a pharmaceutical and biotech executive ... Over the course of his career, he has interfaced with the ...
(Date:1/19/2017)... , Jan. 19, 2017 The Global Therapy ... and access to partnering deals and agreements entered into ... in partnering deals - Top deals by value - ... development, technology type The report provides understanding and ... by the world,s leading healthcare companies. The report ...
Breaking Medicine Technology: