Navigation Links
Increased risk for breast cancer death among black women greatest during first 3 years postdiagnosis
Date:10/28/2012

SAN DIEGO Non-Hispanic black women diagnosed with breast cancer, specifically those with estrogen receptor-positive tumors, are at a significantly increased risk for breast cancer death compared with non-Hispanic white women.

"This difference was greatest in the first three years after diagnosis," said Erica Warner, M.P.H., Sc.D., a postdoctoral fellow at Harvard School of Public Health in Boston, Mass., who presented the data at the Fifth AACR Conference on The Science of Cancer Health Disparities, held here Oct. 27-30, 2012.

Prior research has shown that non-Hispanic black women have lower breast cancer survival rates relative to other racial/ethnic groups.

Warner and colleagues conducted a study of 19,480 women who presented to National Comprehensive Cancer Network centers with stage 1 to stage 3 breast cancer between January 2000 and December 2007. They compared breast cancer-specific mortality among 634 Asian women, 1,291 Hispanic women, 1,500 non-Hispanic black women and 16,055 non-Hispanic white women.

After a median follow-up of 6.9 years, the researchers found that non-Hispanic black women had a 48 percent higher risk for breast cancer death in the first three years after diagnosis compared with non-Hispanic white women. After three years, non-Hispanic black women had a 34 percent increased risk for breast cancer-specific mortality.

"The higher risk for early death among black women was more striking among women with estrogen receptor-positive tumors," Warner said.

Non-Hispanic black women with estrogen receptor-positive tumors were more than twice as likely to die from breast cancer within the first three years of diagnosis compared with non-Hispanic white women. This risk was also increased in non-Hispanic black women with luminal A and luminal B breast cancer subtypes.

"This finding is important because these are the types of tumors that we traditionally think of as more treatable," Warner said.

No difference in breast cancer mortality between non-Hispanic black and white women was found for estrogen receptor-negative, basal or HER2-overexpressing tumor subtypes.

Warner and colleagues also evaluated breast cancer survival among Asian and Hispanic women. Compared with non-Hispanic white women, data indicated that Asian women had a 40 percent lower risk for breast cancer death. The researchers observed this decreased risk in all breast cancers and in estrogen receptor-negative, luminal A and HER2-overexpressing tumors. They found no significant differences between non-Hispanic white women and Hispanic women for breast cancer mortality.

"The results of this study emphasize that clinical management and follow-up for patients with breast cancer, particularly black women, is important in the first few years after diagnosis," Warner said. "Although the difference between blacks and whites was highest for this time period, the risk for death was highest in the first few years after diagnosis for all groups."


'/>"/>
Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research
Source:Eurekalert

Related medicine news :

1. High-risk carotid artery plaque formation is increased in older COPD patients
2. Foot Ulcers Tied to Increased Death Risk for People With Diabetes
3. Steroid injection linked to increased risk of bone fractures
4. Experts call for increased neonatal inclusion in pediatric drug trials
5. Early menopause associated with increased risk of heart disease, stroke
6. Substance-use disorders linked to increased risk of death for veterans with PTSD
7. No increased risk of cancer for people with shingles
8. Shingles Not Linked to Increased Cancer Risk, Study States
9. Attractive names sustain increased vegetable intake in schools
10. Increased dietary fructose linked to elevated uric acid levels and lower liver energy stores
11. Low ghrelin - Reducing appetite at the cost of increased stress?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... The American Board of Family Medicine's (ABFM) Board of Directors has selected ... Dr. James C. Puffer upon his retirement. Dr. Newton will serve in the position ... the end of 2018. Upon assuming the role of President and CEO on January ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes ... a mock evacuation of the facility as part of a disaster drill on October ... Hose EMS and Shelton City Emergency Manager, as well as the Connecticut Long ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
(Date:10/12/2017)... ... 2017 , ... First Healthcare Compliance (FHC), an industry leader ... range of technology and learning solutions at the 68th Annual American Healthcare Association ... held October 14–18, 2017 at the Mandalay Bay Resort in Las Vegas, Nevada. ...
(Date:10/12/2017)... ... 2017 , ... The American College of Medical Informatics (ACMI) will present the ... Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium ... a pioneer in the field of medical informatics, this prestigious award is presented to ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance ... a medical-grade battery-powered display stand specifically designed for endoscopy environments. An ... technology into a clinical solution to support the improvement of patient ... Innovative Design ... Wireless Solution ...
(Date:10/5/2017)... , Oct. 5, 2017  In response ... of Oral and Maxillofacial Surgeons (AAOMS) released prescribing ... – to be used as a first-line therapy ... Recognizing the ... AAOMS White Paper "Opioid Prescribing: Acute and Postoperative ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017 ... of single-use, self-contained, illuminating medical devices, today announced ... National Health Surveillance Agency (or Agência Nacional de ... The first single-use, cordless surgical retractor with integrated ... provides optimal access, illumination and exposure of a ...
Breaking Medicine Technology: