Navigation Links
Increased cancer risk of people with type 2 diabetes
Date:5/21/2010

Cancer and diabetes are risk factors the same for these two diseases? Or does diabetes cause processes in the body which promote the onset or growth of cancer? It is still unclear why diabetics have a higher rate of cancer than people who are not affected by this metabolic disorder.

In order to precisely identify the types of cancer in which diabetes plays a role, Kari Hemminki of DKFZ collaborated with colleagues in Sweden and the United States to carry out the largest study ever on cancer risks of people with type 2 diabetes. The study included 125,126 Swedish citizens who had been hospitalized due to problems associated with type 2 diabetes. The epidemiologists compared the cancer incidence in these patients with that of the general population in Sweden.

The scale of the study also made it possible, for the first time, to quantify correlations between diabetes and less common types of cancer. The researchers discovered that people with type 2 diabetes have an increased risk of developing 24 of the types of cancer studied. The most significant risk elevation was established for pancreatic and liver cell cancers. The rate of these cancers in people with type 2 diabetes is elevated by factor six and 4.25 respectively compared to the general population. The epidemiologists also found the risk of cancers of the kidneys, thyroid, esophagus, small intestine and nervous system to be more than twice as high.

In addition, the study confirmed an observation suggesting that people with type 2 diabetes have a significantly lower rate of prostate cancer. This was particularly apparent in diabetes patients with a family history of the disease. The more family members are affected by diabetes, the lower is the personal prostate cancer risk. "Right now, we can only speculate about the causes," said Hemminki. "Possibly, a lower level of male sex hormones in diabetics may be among the factors that are responsible for this."

Could it be that cancer rates in study participants with type 2 diabetes appear to be increased just because their tumors happened to be found earlier as a result of hospital routine diagnostics? To rule this out, the researchers separately analyzed how many cancers had occurred in study participants after one and five years respectively following their hospital stays. Although this revealed a slightly lower risk elevation, the trend was the same.

In the industrialized countries, between two and twenty percent of the population get type 2 diabetes. Hence, this metabolic disease ranges among the greatest challenges for the public healthcare system. Type 2 diabetes, which used to be incorrectly called "old age diabetes", is characterized by insulin resistance in tissue. It means that the cells of those affected do not take up glucose from the blood upon receipt of an insulin signal.


'/>"/>

Contact: Dr. Sibylle Kohlstaedt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres
Source:Eurekalert

Related medicine news :

1. Economic Recovery and New Healthcare Legislation: The Stars Are Aligned for Increased Adoption of HR Management Systems (HRMS)
2. Traffic density and increased BMI linked
3. Spouses of dementia sufferers have a 6-fold increased risk of dementia onset
4. African-American infants at increased risk from tobacco smoke exposure
5. Kids Raised by Relatives Face Increased Health Risks
6. Summer Brings Increased Demand For Breast and Body Enhancement
7. Obesity associated with increased risk of fibromyalgia
8. Excessive alcohol consumption may lead to increased cancer risk
9. Increased EGFR levels may be an early marker of breast cancer
10. San Francisco Firefighters: Increased Risk for Bladder Cancer – Testing Underway
11. Children of combat-deployed parents show increased worries, even after parent returns
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ... December 07, 2016 , ... ... Campaign Winner in the Folio: Marketing Awards competition. Live From won in the ... in pioneering, inventive, and ultimately successful projects undertaken by the media industry’s most ...
(Date:12/7/2016)... ... 2016 , ... "ProBrand Flip allows FCPX editors to create unique logo reveals ... of Pixel Film Studios. , ProBrand Flip includes 30 flip book reveal animations. Easily ... from a variety of flip book animations. In Addition, users can modify each preset ...
(Date:12/7/2016)... ... December 07, 2016 , ... Bioelectronic ... Plus for consumers and healthcare professionals to manage chronic and acute pain. ... treatment modalities available in a single device. The announcement is part of ...
(Date:12/7/2016)... ... 2016 , ... “The Road To Restoration”: an informative and enlightening book ... a week showing of hands. “The Road To Restoration” is the creation of published ... with the brass ring that you could reach out for, and grab, on the ...
(Date:12/7/2016)... ... December 07, 2016 , ... “Walking With God: Inspirational Lessons ... will inspire the reader to be aware of God's direction in their lives. “Walking ... Sanford Smith, retired teacher and active church leader. , Sanford says, “I ...
Breaking Medicine News(10 mins):
(Date:12/6/2016)... With opioids commonly used for pain management for workplace ... that has led to nationwide fatalities. The synthetic opioid ... than heroin or morphine, resulting in likelihood of addiction, abuse or ... , , ... operations, Behavioral Health for HMC HealthWorks, explained the opioid drug is ...
(Date:12/6/2016)... Dec. 6, 2016  Viking Therapeutics, Inc. ("Viking") ... company focused on the development of novel therapies ... the U.S. Food and Drug Administration (FDA) has ... treatment of X-linked adrenoleukodystrophy (X-ALD).  VK0214 is a ... that selectively regulates the expression of genes believed ...
(Date:12/6/2016)... Mass. , Dec. 6, 2016  Blueprint Medicines ... discovering and developing targeted kinase medicines for patients with ... an underwritten public offering of $125,000,000 million in shares ... to grant the underwriters a 30-day option to purchase ... of its common stock in connection with the public ...
Breaking Medicine Technology: