Navigation Links
Increased cancer risk of people with type 2 diabetes

Cancer and diabetes are risk factors the same for these two diseases? Or does diabetes cause processes in the body which promote the onset or growth of cancer? It is still unclear why diabetics have a higher rate of cancer than people who are not affected by this metabolic disorder.

In order to precisely identify the types of cancer in which diabetes plays a role, Kari Hemminki of DKFZ collaborated with colleagues in Sweden and the United States to carry out the largest study ever on cancer risks of people with type 2 diabetes. The study included 125,126 Swedish citizens who had been hospitalized due to problems associated with type 2 diabetes. The epidemiologists compared the cancer incidence in these patients with that of the general population in Sweden.

The scale of the study also made it possible, for the first time, to quantify correlations between diabetes and less common types of cancer. The researchers discovered that people with type 2 diabetes have an increased risk of developing 24 of the types of cancer studied. The most significant risk elevation was established for pancreatic and liver cell cancers. The rate of these cancers in people with type 2 diabetes is elevated by factor six and 4.25 respectively compared to the general population. The epidemiologists also found the risk of cancers of the kidneys, thyroid, esophagus, small intestine and nervous system to be more than twice as high.

In addition, the study confirmed an observation suggesting that people with type 2 diabetes have a significantly lower rate of prostate cancer. This was particularly apparent in diabetes patients with a family history of the disease. The more family members are affected by diabetes, the lower is the personal prostate cancer risk. "Right now, we can only speculate about the causes," said Hemminki. "Possibly, a lower level of male sex hormones in diabetics may be among the factors that are responsible for this."

Could it be that cancer rates in study participants with type 2 diabetes appear to be increased just because their tumors happened to be found earlier as a result of hospital routine diagnostics? To rule this out, the researchers separately analyzed how many cancers had occurred in study participants after one and five years respectively following their hospital stays. Although this revealed a slightly lower risk elevation, the trend was the same.

In the industrialized countries, between two and twenty percent of the population get type 2 diabetes. Hence, this metabolic disease ranges among the greatest challenges for the public healthcare system. Type 2 diabetes, which used to be incorrectly called "old age diabetes", is characterized by insulin resistance in tissue. It means that the cells of those affected do not take up glucose from the blood upon receipt of an insulin signal.


Contact: Dr. Sibylle Kohlstaedt
Helmholtz Association of German Research Centres

Related medicine news :

1. Economic Recovery and New Healthcare Legislation: The Stars Are Aligned for Increased Adoption of HR Management Systems (HRMS)
2. Traffic density and increased BMI linked
3. Spouses of dementia sufferers have a 6-fold increased risk of dementia onset
4. African-American infants at increased risk from tobacco smoke exposure
5. Kids Raised by Relatives Face Increased Health Risks
6. Summer Brings Increased Demand For Breast and Body Enhancement
7. Obesity associated with increased risk of fibromyalgia
8. Excessive alcohol consumption may lead to increased cancer risk
9. Increased EGFR levels may be an early marker of breast cancer
10. San Francisco Firefighters: Increased Risk for Bladder Cancer – Testing Underway
11. Children of combat-deployed parents show increased worries, even after parent returns
Post Your Comments:
(Date:12/1/2015)... ... December 02, 2015 , ... The National Association of ... into its VIP Woman of the Year Circle. She is recognized with this ... exclusively for professional women, boasting 850,000 members and, over 200 operating Local Chapters. ...
(Date:12/1/2015)... D.C. (PRWEB) , ... December 01, 2015 , ... ... updated, comprehensive website detailing the important role that meat and poultry play ... in meat and poultry, a nutrition quiz where visitors can check their “meat ...
(Date:12/1/2015)... ... December 01, 2015 , ... Integrated Rental Services (“Integrated ... Industries International, LLC (“JII”). , With support from JII, Integrated Rental is poised ... hospitals, surgery centers, clinics, research labs and medical facilities across the United States. ...
(Date:12/1/2015)... ... December 01, 2015 , ... Califia Farms , one of the ... bottle has won top honors in Beverage World Magazine’s Global Packaging Design Awards, taking ... it has been selected as a 2015 U.S.A. Taste Champion in the American Masters ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... we have seen vast improvements in scientific research and discoveries, leading us to ... increased hope and relief to those affected by HIV/AIDS. Mediaplanet’s cross-platform edition of ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... 1, 2015 --> ... Drugs Market by Type of Drug (Monoclonal Antibodies, Interferon-Alpha, Interleukins, ... and Pipeline Analysis - Global Forecast to 2020", published by ... USD 73,529.2 Million by 2020 from USD 40,281.6 Million in ... Browse 37 market data ...
(Date:12/1/2015)... BANGALORE, India and PITTSBURGH ... TASE: MYL) today announced that it expects to be ... developing country markets funded by international donors, TLE400 (Tenofovir ... Efavirenz 400 mg) for $99 per patient, per year. ... to develop TLE400. The significantly reduced price could generate ...
(Date:12/1/2015)... , Dec. 1, 2015  AccuTEC Blades, a ... new corporate logo and brand identity program. The ... and engineering of bladed products where "the edge ... --> Serving manufacturers and distributors ... auto glass equipment, AccuTEC,s product lines include those ...
Breaking Medicine Technology: