Navigation Links
In war with 'superbugs,' Cedars-Sinai researchers see new weapon: Immune-boosting vitamin
Date:8/27/2012

LOS ANGELES Aug. 27, 2012 Cedars-Sinai researchers have found that a common vitamin may have the potential to provide a powerful weapon to fight certain "superbugs," antibiotic-resistant staph infections that health experts see as a threat to public health.

The research, published in the September 2012 edition of The Journal of Clinical Investigation, found that high doses of the nicotinamide form of vitamin B3 stimulated a specific gene (CEBPE), enhancing white blood cells' ability to combat staph infections, including methicillin-resistant Staphylococcus aureus or MRSA.

With research ongoing, including possible clinical trials in humans, the scientists caution consumers not to treat a suspected infection by taking vitamin B3. Instead, a physician should be consulted.

"It's critical that we find novel antimicrobial approaches to treat infection and not rely so heavily on antibiotics," said George Liu, MD, PhD, a pediatric infectious disease physician at Cedars-Sinai's Maxine Dunitz Children's Health Center and co-senior author of the study. "That's why this discovery is so exciting. Our research indicates this common vitamin is potentially effective in fighting off and protecting against one of today's most concerning public health threats."

Staph infections commonly cause serious, sometimes life-threatening illness. Health officials fear that indiscriminate use of antibiotics has undercut their effectiveness, leading to the rapid rise and threatening spread of resistant germs.

In laboratory tests with mice and human blood, Cedars-Sinai scientists found that vitamin B3 increased by up to 1,000 fold the ability of the immune system to kill staph bacteria. Beyond its findings related to vitamin B3, the study indicates that similar targeting of the CEBPE gene with other compounds may offer a new immune-boosting strategy to fight bacterial infections.

The researchers have been investigating
'/>"/>

Contact: Nicole White
nicole.white@cshs.org
310-423-5215
Cedars-Sinai Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Cedars-Sinai stroke team earns award for improving regions quality of care
2. Cedars-Sinai physician definitively links irritable bowel syndrome and bacteria in gut
3. Cedars-Sinai researchers, with stem cells, advance understanding of spinal muscular atrophy
4. Cedars-Sinai Medical Center studies galaxy-exploring camera in the operating room
5. Cedars-Sinai awarded $17.8 million grant to develop ALS treatment
6. NIH awards $20 million over 5 years to train next generation of global health researchers
7. Researchers develop a new cell and animal model of inflammatory breast cancer
8. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
9. Researchers Find Gene Mutations That May Be a Key to Autism
10. Researchers find evidence of banned antibiotics in poultry products
11. NJ stroke researchers report advances in spatial neglect research at AAN Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... Chicago, IL (PRWEB) October 30, 2014 Dr. ... launched a new website for his practices; OB GYN ... Chicago, IL . This website contains important information about ... covers as well as downloadable patient forms in English and ... use and the service pages on the website provide Dr. ...
(Date:10/30/2014)... Rock Hill, South Carolina (PRWEB) October 30, 2014 ... a muscle, and should be more vigorously exercised to ... Grewal. He recently authored the book ‘Dementia Express: Lose ... , The book uses counterintuitive reasoning and sometimes conflicting ... an obstacle course for the mind, a reader must ...
(Date:10/30/2014)... who used stem cells to create miniature human stomachs ... new way to learn more about the development and ... pluripotent stem cells -- which can become any type ... functional miniature stomachs, to study infection by H. ... stomach cancer. The miniature stomachs offer many research ...
(Date:10/30/2014)... WEDNESDAY, Oct. 29, 2014 (HealthDay News) -- Americans, opinions ... political lines, a new study finds. Democratic voters ... (ACA), according to the researchers. Almost three-quarters of Democrats ... ACA. Thirty percent want Congress to implement the current ... of the ACA. Among Independent voters, one-third want ...
(Date:10/29/2014)... women at first acted surprised. Some insisted the blood tests ... not used the study products assigned to them as participants ... likely consequence, did not find any of the three products ... were among 127 former VOICE participants who, as part of ... in in-depth interviews and/or focus group discussions after learning the ...
Breaking Medicine News(10 mins):Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:‘Dementia Express’ Offers Contradictory and Sometimes Reverse Thinking, All to Keep its Reader on Their Toes With an Active Mind. 2Health News:Voters' Views on Obamacare Split Along Party Lines 2Health News:Women who took part in VOICE speak up about why they didn't use HIV prevention products 2Health News:Women who took part in VOICE speak up about why they didn't use HIV prevention products 3
... of hormone worsened respiratory disease , , THURSDAY, Nov. 20 ... may explain why women with cystic fibrosis tend to ... at the University of North Carolina report. , , ... 20 issue of the Journal of Clinical Investigation ...
... Reno,s Downtown Ballroom was transformed into a Cirque style extravaganza ... ballroom to help raise funds for one of Reno,s most ... residents and many of Nevada,s prominent leaders, including Nevada Governor ... To view the Multimedia News Release, go to: ...
... Nov. 20 Precyse Solutions, the leader in,driving ... management solutions, was recognized by the Eastern Technology,Council ... at the 16th,Enterprise Award Gala held at the ... top technology and life sciences companies and entrepreneurs. ...
... at risk for hospital visits of their own , , THURSDAY, ... for a loved one with Alzheimer,s results in 25 percent ... hospital visit every six months, says an Indiana University study. ... an Alzheimer,s patient is difficult, but the Indiana University researchers ...
... Quality Care , ARLINGTON HEIGHTS, Ill., Nov. 20 ... cannot afford to cut corners on quality of care, warns ... thing to temporarily substitute fillers for facelifts, ASPS says the ... professional training. This concern was discussed recently at the ASPS ...
... People are often reluctant to undergo a routine but ... be fatal. According to the American Cancer Society, colon ... American men and women and kills about 50,000 Americans ... cancer have no symptoms or family history," says Prof. ...
Cached Medicine News:Health News:Estrogen May Explain Why Women With Cystic Fibrosis Suffer More 2Health News:Estrogen May Explain Why Women With Cystic Fibrosis Suffer More 3Health News:Photos: Nevada's Saint Mary's Regional Medical Center Raises $1.3 Million During Centennial Soiree 2Health News:Precyse Solutions Honored as 'Technology Company of the Year' 2Health News:When the Caregiver Becomes the Patient 2Health News:Caution Urged as Patients Seek Deals on Cosmetic Surgery 2Health News:A simple blood test for colon cancer 2
(Date:10/30/2014)... 30, 2014 Today Eli Lilly and Company ... long-standing technology transfer program to increase the global supply ... the effort included Lilly donating manufacturing technology and know-how ... China , India , ... – all MDR-TB ,hot spots., It also ...
(Date:10/27/2014)... , 27 de octubre de 2014 /PRNewswire/ ... menudo conocida como ardor de estómago, es un ... mundo. [1] La elección de alimentos [2] ... un impacto en los síntomas de la GERD. ... ayudar a las personas a gestionar los síntomas ...
(Date:10/27/2014)... -- In the last few weeks, Ebola has gone from a localized ... a worldwide crisis when a traveler to United States ... nurses were infected. While much of the cable news ... technology, such as electronic health records (EHRs), to help find, combat, ... Healthcare Editor Alison Diana fills in those gaps by ...
Breaking Medicine Technology:Lilly Shares Insights from Decade-Long Technology Transfer Experience 2Lilly Shares Insights from Decade-Long Technology Transfer Experience 3Lilly Shares Insights from Decade-Long Technology Transfer Experience 4Trate los síntomas del reflujo gracias a la Food4GERD App 2Trate los síntomas del reflujo gracias a la Food4GERD App 3Trate los síntomas del reflujo gracias a la Food4GERD App 4EHRs in the Age of Ebola: Discuss on InformationWeek 2EHRs in the Age of Ebola: Discuss on InformationWeek 3
... Industry-Funded Immune Globulin Study Uncovers Sample,Manipulation, Design ... -- An analysis,released today critically examined a ... autism and Rh immune globulin,(RhIg) injections, some ... extensive design flaws, the,analysis uncovered manipulation of ...
... OSS, the Netherlands, June 27, 2007-Organon, the human,healthcare ... two,out of three Phase III clinical trials with ... have reached,their randomization target. , ,Corifollitropin alfa ... first of a new class of gonadotropins (a ...
Cached Medicine Technology:Genetics Journal Thimerosal/Autism Study the 'Best Science Drug,Company Money Can Buy' 2Genetics Journal Thimerosal/Autism Study the 'Best Science Drug,Company Money Can Buy' 3Two Phase III clinical trials on corifollitropin alfa (Org 36286),reach randomization target 2Two Phase III clinical trials on corifollitropin alfa (Org 36286),reach randomization target 3
... Millipore has developed a range of ... match specific water quality requirements. Each ... is designed to specifically target contaminants ... HPLC, molecular biology and ICP-MS. The ...
Inquire...
... the Mo Bio Vortex Adapter in conjunction with ... procedures. Using the Mo Bio Vortex Adapter ... and Fast Prep machines which offer the same ... ml) centrifuge tubes at one time and will ...
... Combines BchiVac V-500 with Vacuum ... Efficiently controls vacuum levels from ... pump designed to handle most vacuum applications. ... up to two rotary evaporators Laboratory ...
Medicine Products: