Navigation Links
In vitro models will minimize animal use in arthritis studies
Date:10/17/2007

COLUMBIA, Mo. Its hard to think of scientists in laboratories working toward solutions for medical problems without mice or other laboratory animals, but animals roles in at least one major research laboratory may soon be minimal.

Researchers at the University of Missouri-Columbia's Comparative Orthopaedic Laboratory (COL) have developed an in vitro model using small sections of joint capsule and cartilage typically discarded that mimics arthritic joints. This "joint in a test tube" model can be used to investigate causes and mechanisms for the development and progression of arthritis and to screen new treatments such as pharmaceuticals. The MU research team which developed this model has shown that the results have valid and direct clinical implications for arthritis in dogs and humans.

Often, clinical research is limited by patient numbers, accessibility to appropriate samples and ethical considerations. Using in vitro models eliminates some of these barriers and allows researchers to better understand of the diseases development, characteristics and responses to various injuries, treatments and loads. The in vitro model acts similar to an actual joint with the same histological, biochemical and molecular changes.

These in vitro models will allow us to perform our research without using animals while still accurately mimicking situations in real life, said James Cook, professor of veterinary medicine and surgery and the William C. Allen Endowed Scholar for Orthopaedic Research. We can screen new drugs for arthritis in a more efficient and cost-effective way such that real progress is achieved more quickly.

The in vitro models allow for all of the tissue in a normal joint to be "grown" together such that the different types of tissues can "communicate" as they do in the actual joint. COL researchers have shown that this system maintains the tissues' appearance, composition, and function so that they react to health
'/>"/>

Contact: Christian Basi
BasiC@missouri.edu
573-882-4430
University of Missouri-Columbia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Functional Taste Cells Cultured In Vitro
2. Alcoholism Drug Vivitrol Approved By FDA
3. Scientists Create Live Birth Using Artificial Sperms Produced In Vitro
4. Chinas Neusoft and Trivitron Plan to Set up Medical Equipments Unit
5. HPV Could Hamper Success Rates of In Vitro Fertilization
6. In Vitro Treatment Only When Both Partners Agree, Rules European Court
7. Questions Raised Over Safety of In-vitro Fertilization
8. Womens Self-Esteem Not Lowered By Seeing Ultra Thin Models
9. Mouse Models To Determine The Cause Of Aggressive Leukemia
10. Spanish Fashion Show Rejects Five Models as too Thin
11. Academy for Eating Disorders Calls for Ban on Underweight Models
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... 21, 2014 Top10BestSEOHosting.com is a ... about hosting products. It is headed by a ... The site offers research-based information and factual studies ... in the current market. , Recently, Top10BestSEOHosting.com ... that GoDaddy and Bluehost are the ...
(Date:8/20/2014)... City, UT (PRWEB) August 20, 2014 ... Benefits Solution, announced the publication of a new ... Zane Benefits, many small business owners feel uncertain ... employees, their family, and their bottom line. , ... comprehensive FAQs, and helps businesses navigate their upcoming ...
(Date:8/20/2014)... (HealthDay News) -- A group representing U.S. obstetricians is ... shot. According to the American College of Obstetricians ... have upheld the safety and effectiveness of flu vaccination ... and can be particularly dangerous to pregnant women, as ... Dr. Laura Riley, chair of the college,s Immunization Expert ...
(Date:8/20/2014)... of women underwent breast reconstruction following a mastectomy ... reconstruction included being black, having a lower education ... M.D., of the Memorial Sloan Kettering Cancer Center, ... Health and Cancer Rights Act in 1998 guaranteed ... Still, most women who undergo a mastectomy do ...
(Date:8/20/2014)... August 20, 2014 Hundreds of Mirena ... of women who were allegedly injured due to spontaneous ... New Jersey’s Bergen County Superior Court, Bernstein Liebhard LLP ... August 15, 2014, the Court has established procedures regarding ... lawsuits that are part of the proceeding’s initial disposition ...
Breaking Medicine News(10 mins):Health News:New Reviews For Linux Web Hosting Suppliers Announced By Top10BestSEOHosting.com 2Health News:All Pregnant Women Need Flu Shot: Ob/Gyn Group 2Health News:Patient perspectives on breast reconstruction following mastectomy 2Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 3Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 4
... said that people were offered places in hotels it was ... defending their decision to house hospital patients in Aberdeen hotel ... Grampian said a doctor always took the decision as to ... outwith the city's Royal Infirmary. She said that as the ...
... is a fungal infection affecting mostly children in North America. ... affected by ringworm infections. //It is a highly contagious skin ... symptoms such as scaly scalp and hair loss which can ... household pets but in rare occasions it is passed easily ...
... the poor quality of drinking water for the cholera cases ... 222 cases have been reported.// ,"The capital has reported ... last year. But we are not triggering the warning bell ... deputy municipal health officer of Delhi. ,"Waterborne diseases ...
... in New Zealand have warned against using traditional Indian ... it was reported Friday.// ,"We wish to alert ... posed by a particular form of herbal remedy, namely, ... latest New Zealand Medical Journal. ,The eight ...
... Court has demanded an explanation from the medical superintendent (MS) ... from cancer got inflicted with AIDS after undergoing blood transfusion ... on why the relevant documents were not being made available ... that the blood transfusion was the business of the public ...
... of an influenza pandemic set into action by mutations of the ... handle// a mega crisis, and what plan of action can we ... an epidemic, eight Asia Pacific countries are teaming up next month ... of a global response to a pandemic. ,Australia and ...
Cached Medicine News:
(Date:8/20/2014)... , Aug. 20, 2014  The National Association ... latest results achieved by the real-time, pseudoephedrine (PSE) ... National Precursor Log Exchange (NPLEx), automatically blocks unlawful ... down methamphetamine offenders and make arrests. Data released ... Michigan blocked the sale of more ...
(Date:8/20/2014)... 2014 Reportlinker.com announces that a ... its catalogue: Personal Accident and ... Opportunities to 2018 ... provides in depth market analysis, information and ... health insurance segment, including: - The French ...
(Date:8/20/2014)... , Aug. 20, 2014 ... of the "Global Biosimilars/Follow-on-Biologics Market (Technology, Types, ... - 2020" report to their offering. ... market (types, applications and geography) - Size, Share, ... Report, Opportunities, Segmentation and Forecast, 2013 - 2020", ...
Breaking Medicine Technology:Michigan's Stop-Sale System Achieves Significant Results In Battle Against Meth 2Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 2Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 3Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 4Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 5Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 6Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 7Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 8Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 9Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 10Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 11Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 12Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 13Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 14Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 15Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 16Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 17Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 18Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 19Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 20Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 21Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 22Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 23Global Biosimilars/Follow-on-Biologics Market (Technology, Types, Applications, Services and Geography) - Research Report, 2013 - 2020 2
... XI,AN, China , ... (OTC Bulletin Board: HFGB), specializing,in developing and producing ... food additives, today announced the receipt of its,European ... from Galenicum,Health S.L., a Spanish pharmaceutical company. This ...
... DIEGO , July 22 MabVax Therapeutics Inc., ... development of vaccine and antibody based therapies to address the ... first patients have been enrolled in a Phase II clinical ... vaccine to prevent or delay the recurrence of sarcoma. The ...
Cached Medicine Technology:Huifeng Bio-Pharmaceutical Technology Announces a New Spain Order 2Huifeng Bio-Pharmaceutical Technology Announces a New Spain Order 3MabVax Therapeutics Initiates Phase II Clinical Trial of Vaccine to Prevent Recurrent Sarcoma 2MabVax Therapeutics Initiates Phase II Clinical Trial of Vaccine to Prevent Recurrent Sarcoma 3
... The first step to treatment is accurate ... an innovative and quick, patient-friendly tool designed ... urinary incontinence while minimizing patient discomfort. Designed ... features a new type of urethral pressure ...
...
...
...
Medicine Products: