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In retinal disease, sight may depend on second sites
Date:5/12/2009

gene increases the risk for retinal degeneration in patients with ciliary diseases caused by other genes.

Ciliary diseases can cause a variety of symptoms in patients, including kidney failure, nervous system defects, extra fingers and toes, and progressive blindness. According to Katsanis, whether a patient goes blind depends on modifiers like A229T. "A229T increases one's risk 10 percent to go blind," says Katsanis. "But it's only one single genetic change of many possible. Now we want to collect all modifier information so we can develop specific drug information and specific treatment regimens."


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Contact: Audrey Huang
audrey@jhmi.edu
410-614-5105
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3

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