Navigation Links
In children born with severe heart defect, surgical management has little effect on neuro outcomes
Date:4/5/2012

neurodevelopmental outcomes. "Between Norwood discharge and age 12 months, a greater number of complications were also associated with worse development, a novel finding that highlights ongoing brain vulnerability and opportunities for intervention," said Newburger. Longer recovery times and prolonged mechanical ventilation may involve other factors during hospitalization, such as adverse events, low cardiac output, poor feeding or comorbidities.

"The finding that postnatal factors had only modest effects on neurodevelopment is consistent with growing evidence that the risk for adverse neurodevelopmental outcomes begins in the prenatal period," added Gaynor. Patients with HLHS have a high rate of abnormal cerebral development and smaller head size, suggesting that genetic factors and epigenetic changes contribute to brain abnormalities. Researchers have identified abnormalities in fetal cerebral blood flow and in brain metabolism and microstructure, all indicative of brain immaturity in fetuses and neonates with this heart defect. These delays in brain maturation, said Gaynor, may increase the infant's vulnerability to circulatory injury in the brain during the operative period.

Further studies may reveal interventions that improve neurodevelopmental outcomes in these children, conclude the authors. In addition to discouraging elective deliveries before 39 weeks, they suggest evaluating further measures to protect the brain from hemodynamic instability before and after the surgery, and improving developmental support after the infant is discharged following the Norwood procedure.


'/>"/>

Contact: Joey McCool Ryan
McCool@email.chop.edu
267-426-6070
Children's Hospital of Philadelphia
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Amway One by One Campaign for Children Reaches 7 Million Kids
2. Exposure to secondhand smoke among children in England has declined since 1996
3. One Month after Major Quake, Ongoing Crises for Haitian Children
4. Groundbreaking Principal and Contributor on Dr. Oz Show Releases His Latest Book on How We Can Influence the Lives of Children
5. Children With Cerebral Palsy Benefitting From New Physical Therapy Regimen
6. Als Angels Love and Laughter Event to Support Children and Families in Desperate Need
7. If children wont go to school
8. Parents often wait too long to treat childrens asthma symptoms
9. Hypnosis can relieve symptoms in children with respiratory diseases
10. National Network of Digital Schools, SlateXP and UMPS CARE Raise $75,000 for Children
11. Father Channels His Grief into Advocacy, Promotes Simple Actions to Make Hospitals Safer for Children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... 23, 2014 Celebrating a decade of ... today announced the awarding of $1,070,000 in grants to ... in recognition of the Foundation’s 1,000th grant. , “The ... our tradition of supporting community-based organizations that are working ... life in the Garden State,” said Robert A. Marino, ...
(Date:7/23/2014)... a growing body of research suggesting a safe ... treating postmenopausal breast cancer, with fewer detrimental side ... anti-hormone therapies. The study will be published in ... Reproductive Biology and Endocrinology . , Breast cancer ... in the United States. Approximately 70% of breast ...
(Date:7/23/2014)... 23, 2014 Global Cardio Care, Inc., ... External Counterpulsation (EECP), is celebrating the 100th birthday ... at the health center. , Weber has been ... receiving ongoing EECP therapy since 1999, he no longer ... CEO of Global Cardio Care, introduced the Sara ...
(Date:7/23/2014)... The voice on the recording was low and ... news he was infected with the human immunodeficiency virus (HIV) that ... next thing you know I was on the floor flat on ... was hopeful when the recording ended less than 10 minutes later. ... . because it is just God setting you up for ...
(Date:7/23/2014)... WEDNESDAY, July 23, 2014 (HealthDay News) -- For patients ... antiretroviral therapy may help control both viruses, a small ... findings to improve treatment strategies for people with the ... suppression with antiretroviral medications plays an important role in ... infection," said study leader Dr. Kenneth Sherman, a professor ...
Breaking Medicine News(10 mins):Health News:The Horizon Foundation for New Jersey Awards More than $1 million in Grants to 20 Non-profit Organizations 2Health News:The Horizon Foundation for New Jersey Awards More than $1 million in Grants to 20 Non-profit Organizations 3Health News:The Horizon Foundation for New Jersey Awards More than $1 million in Grants to 20 Non-profit Organizations 4Health News:The Horizon Foundation for New Jersey Awards More than $1 million in Grants to 20 Non-profit Organizations 5Health News:Hormones after breast cancer: Not fuel for the fire after all? 2Health News:Hormones after breast cancer: Not fuel for the fire after all? 3Health News:Hormones after breast cancer: Not fuel for the fire after all? 4Health News:Hormones after breast cancer: Not fuel for the fire after all? 5Health News:Global Cardio Care Celebrates EECP Patient’s 100th Birthday 2Health News:HIV clinic-based audio project emphasizes the power of patient voices 2Health News:HIV clinic-based audio project emphasizes the power of patient voices 3Health News:HIV Meds May Also Help Control Hepatitis C, Study Finds 2
... , , , , ANAHEIM, Calif., June ... entertainment, public health and justice professionals, and Drug Court graduates gathered ... and call for a Drug Court to be put within reach ... Court Professionals (NADCP) 15th Annual Training Conference. , , ...
... common cancers in China. Although the association between the ... the relation between smoking, alcohol drinking, family history of ... still remains uncertain. So it is important to investigate ... sporadic colorectal cancer. A research team led by ...
... Health Insurer Hires 200th Employee , , Momentum Builds ... Health Care Insurance Crisis , , AVENTURA, Fla., June ... health insurance benefit programs for the consumer market, today announced ... "Cinergy Health is a company with a clear mission -- ...
... ... & Public Relations® (BSAPR) a full-service, integrated strategic marketing services firm, today announced ... ... 2009 -- Blanchard Schaefer Advertising & Public Relations ® (BSAPR) a full-service, ...
... Thursday 11 June 2009: Undertaking a supervised exercise ... and physical function, reduce the need for daily ... depression and anxiety in people with rheumatoid arthritis ... at EULAR 2009, the Annual Congress of the ...
... STARTLING TRUTHS , , PALM COAST, Fla., June 11 ... photos are uploaded daily through digital networks such as Facebook and ... like acne have on the life of teens? Based on first ... social traits than if they had clear skin, according to results ...
Cached Medicine News:Health News:U.S. Drug Czar Addresses 2,500 Drug Court Professionals, Voices Strong Support for Expanding Drug Courts Throughout the Nation 2Health News:U.S. Drug Czar Addresses 2,500 Drug Court Professionals, Voices Strong Support for Expanding Drug Courts Throughout the Nation 3Health News:Cinergy Health Expands Staff in Face of Dramatic Growth 2Health News:Blanchard Schaefer Advertising & Public Relations Wins Healthcare Advertising Awards 2Health News:Blanchard Schaefer Advertising & Public Relations Wins Healthcare Advertising Awards 3Health News:Exercise improves functional and psycological ability and reduces steroid need in rheumatoid arthritis 2Health News:Photos: New Image Survey Reveals 'Perception Is Reality' When It Comes to Teenagers With Acne 2Health News:Photos: New Image Survey Reveals 'Perception Is Reality' When It Comes to Teenagers With Acne 3Health News:Photos: New Image Survey Reveals 'Perception Is Reality' When It Comes to Teenagers With Acne 4Health News:Photos: New Image Survey Reveals 'Perception Is Reality' When It Comes to Teenagers With Acne 5
(Date:7/23/2014)... Pharmavite LLC announced that Timothy "Tim" Toll ... immediately. Toll recently served as Pharmavite,s executive vice president ... private label and sales administration in the ... Toll will expand his responsibilities to include international sales, ... appointment to chief customer officer is part of a ...
(Date:7/23/2014)... 2014 On Tuesday, July 1, 2014, ... in the 116 th Judicial District Court ... RegenLab USA, LLC ("Defendant") for ... through false and misleading actions, fraud, fraud-in-the-inducement, ... through libel, disparagement, defamation, misrepresentation, and violating ...
(Date:7/23/2014)... -- RT Oncology Services Corporation today announced that Craig ... directors. Mr. Mundie is currently senior advisor to the ... projects within the company and on technology strategy and ... officer. Mike Martin , president ... a visionary technology executive. His appointment is part of ...
Breaking Medicine Technology:Craig Mundie Joins RainTree Oncology Board of Directors 2Craig Mundie Joins RainTree Oncology Board of Directors 3
... --,Pharmacyclics, Inc. announced today multiple presentations and ... an oral presentation of Phase 3 SMART ... Radiation,Therapy) trial data. The presentations and publications ... American Society of Clinical Oncology,Annual Meeting (ASCO) ...
... Two New Studies Highlight Potential Benefit of ... /PRNewswire/ -- Stimulant drug abuse,remains an ongoing ... to treat Attention Deficit Hyperactivity Disorder,(ADHD). Data ... Meeting of,the American Psychiatric Association highlighted findings ...
Cached Medicine Technology:Pharmacyclics Announces Presentations and Published Abstracts on,Xcytrin at The 2007 American Society of Clinical Oncology Annual,Meeting 2New Data Suggests Less Abuse-Related Effects For OROS,Methylphenidate 2New Data Suggests Less Abuse-Related Effects For OROS,Methylphenidate 3New Data Suggests Less Abuse-Related Effects For OROS,Methylphenidate 4New Data Suggests Less Abuse-Related Effects For OROS,Methylphenidate 5
West 2 periosteal elevators....
Alexander periosteal elevators....
Sedillot periosteal elevators....
Modified Freer periosteal elevator, #163, slight curve, 21 cm....
Medicine Products: