Navigation Links
In children born with severe heart defect, surgical management has little effect on neuro outcomes
Date:4/5/2012

unt group would fare better in neurodevelopmental tests, reasoning that cerebral blood flow was improved compared to that provided by the Blalock-Taussig shunt. However, neurodevelopmental delay remained common in both groups, a finding that was "discouragingly similar" to results from earlier studies, said J. William Gaynor, M.D., pediatric cardiothoracic surgeon at The Children's Hospital of Philadelphia and senior author of the study. Factors such as the presence of genetic syndromes, lower maternal education and lower birth weight led to lower development scores.

The current study included infants from 15 participating centers, recruited between May 2005 and July 2008. The researchers evaluated 321 infants at 14 months of age. Neurodevelopment was assessed using the Bayley Scales of Infant Development Second Edition, a standardized assessment of cognitive and motor development, with two scores: the Psychomotor Development Index (PDI) and the Mental Development Index (MDI).

MDI scores for the infants who had the Norwood procedure were significantly lower than in the general population, and PDI scores for the cohort were profoundly lowergreater than 2 standard deviations lower in 44 percent of the patients. Infants with both shunt types had similar developmental scores. No characteristics such as center volume or surgeon volume had an effect on PDI or MDI scores, nor did the type of perfusion. The subgroup of patients with the highest PDI and MDI scores, as well as a shorter post-operative hospital stay, were children with no genetic syndrome and birth weights higher than 2.5 kg (5.5 lbs.).

The authors suggested that birth weight might be improved by postponing the time of elective delivery to 39 to 40 weeks. Recent studies have shown that babies with critical congenital heart disease were delivered electively as early as 37 weeks.

The study team found that infants with more post-operative complications tended to have worse
'/>"/>

Contact: Joey McCool Ryan
McCool@email.chop.edu
267-426-6070
Children's Hospital of Philadelphia
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Amway One by One Campaign for Children Reaches 7 Million Kids
2. Exposure to secondhand smoke among children in England has declined since 1996
3. One Month after Major Quake, Ongoing Crises for Haitian Children
4. Groundbreaking Principal and Contributor on Dr. Oz Show Releases His Latest Book on How We Can Influence the Lives of Children
5. Children With Cerebral Palsy Benefitting From New Physical Therapy Regimen
6. Als Angels Love and Laughter Event to Support Children and Families in Desperate Need
7. If children wont go to school
8. Parents often wait too long to treat childrens asthma symptoms
9. Hypnosis can relieve symptoms in children with respiratory diseases
10. National Network of Digital Schools, SlateXP and UMPS CARE Raise $75,000 for Children
11. Father Channels His Grief into Advocacy, Promotes Simple Actions to Make Hospitals Safer for Children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2015)... Final Cut Pro X plugin ... Studios, entitled TranSports. , “TranSports is a compilation ... Pro X,” said Christiana Austin, CEO of Pixel Film ... effortlessly transition using this cool sports transition tool.” , ... styled transition pack for Final Cut Pro X. TranSports ...
(Date:3/28/2015)... March 28, 2015 Could genetic code ... new study by researchers at the Harvard ... with the support of the Coffee and Caffeine Genetics ... Psychiatry this past fall, the study—one of several recent ... genomic data from more than 120,000 regular coffee drinkers ...
(Date:3/28/2015)... The California-based leading wig brand UniWigs has prepared a ... during the Easter Holidays from today until April 6th. ... Fools’ Day. , As the winter fades and spring ... Festival, with religious origins to countries in Europe and ... The best wig provider, UniWigs, would like to offer ...
(Date:3/28/2015)... NV (PRWEB) March 28, 2015 Pitching speed, ... a history of shoulder and elbow injuries, according to new ... Medicine’s ( AOSSM ) Specialty Day. , “Our findings indicate ... a 20% increase in likelihood of a history of injury, ... with a 12% increase likelihood of a history of injury, ...
(Date:3/28/2015)... Raleigh, NC (PRWEB) March 28, 2015 ... people with peritoneal mesothelioma, revealing, for the first time, ... Click here to read the newly posted story ... scientists at the University of British Columbia, the British ... used genome mapping to reveal underlying molecular alterations and ...
Breaking Medicine News(10 mins):Health News:Introducing TranSports for Final Cut Pro X Users from Pixel Film Studios 2Health News:How Coffee Habits Relate to Our Genetic Code and Enhancing the Caffeine Experience 2Health News:How Coffee Habits Relate to Our Genetic Code and Enhancing the Caffeine Experience 3Health News:UniWigs Is Sending Out Mysterious Gifts During the Easter Holidays 2Health News:Researchers Highlight Shoulder and Elbow Injury Possibility in Youth Players 2Health News:New Genomics Research May Help Doctors Tailor Mesothelioma Treatment, According to Surviving Mesothelioma 2
... The increase in the number of U.S. medical students ... sign toward easing the primary care workforce shortage, according ... second-largest doctors group. The 2011 National Resident Matching ... from last year, with 2,940 U.S. seniors at medical ...
... Arbor, Mich. Providing kidney transplants to patients with ... transplant operations and improve life span after kidney transplant, ... the New England Journal of Medicine March 16., Alan ... and his co-authors endorsed new concepts designed to improve ...
... N.J. (March 16, 2011) The Multiple Myeloma Research ... Hackensack University Medical Center, member of the Multiple Myeloma ... in Multiple Myeloma Patient Symposium on Saturday, April 2 ... program is for patients and caregivers who want to ...
... released new official clinical guidelines on the diagnosis ... statement replaces ATS guidelines published in 2000, and ... and management of IPF, as well as available ... palliative care. , The statement appears in the ...
... By Maureen Salamon HealthDay Reporter , ... on Parkinson,s disease patients significantly improved the tremors, rigidity ... the illness, a small new study reports. The ... advanced Parkinson,s disease, with half randomly assigned to receive ...
... shows that it is feasible to screen for undiagnosed ... arrest (SCA). Adding a 10-minute electrocardiogram (EKG or ECG) ... of potentially serious heart conditions. Although more ... relatively low-cost screening might help identify children who are ...
Cached Medicine News:Health News:Residency match results encouraging for adults needing primary care 2Health News:Survival matching should be used to allocate donated kidneys to transplant recipients 2Health News:Survival matching should be used to allocate donated kidneys to transplant recipients 3Health News:The MMRF and John Theurer Cancer Center to host patient symposium 2Health News:ATS issues joint statement on the treatment of idiopathic pulmonary fibrosis 2Health News:ATS issues joint statement on the treatment of idiopathic pulmonary fibrosis 3Health News:ATS issues joint statement on the treatment of idiopathic pulmonary fibrosis 4Health News:Gene Therapy May Help Reverse Parkinson's Symptoms 2Health News:Gene Therapy May Help Reverse Parkinson's Symptoms 3Health News:In pilot study, screening detects potentially serious heart conditions in healthy children 2
(Date:3/27/2015)... 27, 2015 According to a ... Catheter (Conventional, Advanced, Ultrasound), Ablation Catheter (Cryoablation, RF, Microwave), ... (AF, VT, WPW) - Global Forecasts to 2019 ", published ... reach around ~$4.73 Billion by 2019 with a CAGR ... 2019. Browse   90   ma ...
(Date:3/27/2015)... DALLAS , March 27, 2015   ... global leader in biosimilars and the world,s leading ... two studies that support an evaluation of biosimilarity ... U.S. Food and Drug Administration (FDA) conditionally approved ... Amgen,s EPOGEN™ (epoetin alfa). These study data were ...
(Date:3/27/2015)... DALLAS , March 27, 2015 ... Review, H1 2015" therapeutic market research report of ... to its online business intelligence library. ... comprehensive information on the therapeutic development for Visceral ... therapeutics assessment by drug target, mechanism of action ...
Breaking Medicine Technology:Electrophysiology (EP) Market Worth $4.73 Billion by 2019 2Electrophysiology (EP) Market Worth $4.73 Billion by 2019 3Electrophysiology (EP) Market Worth $4.73 Billion by 2019 4Hospira Clinical Data Shows Proposed Biosimilar, Epoetin Hospira, Demonstrates Pharmacokinetic And Pharmacodynamic Equivalence Compared To Amgen's Epogen 2Hospira Clinical Data Shows Proposed Biosimilar, Epoetin Hospira, Demonstrates Pharmacokinetic And Pharmacodynamic Equivalence Compared To Amgen's Epogen 3Visceral Pain Pipeline Review H1 2015 Market Research Report 2Visceral Pain Pipeline Review H1 2015 Market Research Report 3Visceral Pain Pipeline Review H1 2015 Market Research Report 4
... announced today the closing of a $30 million Series B ... fund development of Elevation,s new aerosol therapy for patients living ... in the round, including Canaan Partners , TPG ... Venture Partners . In conjunction with this financing, Elevation has ...
... Calif., Jan. 4, 2012  MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) today ... J.P. Morgan Healthcare Conference on Wednesday, January 11, 2012 at ... webcast of the presentation will be available on the Investor ... A replay also will be available within 24 hours for ...
Cached Medicine Technology:Elevation Pharmaceuticals Completes $30 Million Series B Financing to Advance Aerosol COPD Therapy 2Elevation Pharmaceuticals Completes $30 Million Series B Financing to Advance Aerosol COPD Therapy 3
... gentle and effective surgical scrub with special ... is known to kill skin surface pathogens, ... protozoa and yeasts. It produces a rich ... pre-operative prepping, as well as for pre-and ...
... Aplicare two and four ounce ... meet the needs of procedural ... bottle itself has been custom ... match the cap perfectly. This ...
A patient skin prepping solution in a self-contained applicator combining two proven broad-spectrum antimicrobials: alcohol for fast kill and fast drying (3 minutes on skin), and an iodophor for pers...
Idophor PVP Scrub Winged Sponges...
Medicine Products: