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In a new post-hoc analysis, significantly more patients achieved blood sugar goals with JANUMET
Date:6/25/2011

WHITEHOUSE STATION, N.J., June 25, 2011 In a new post-hoc analysis based on the American Association of Clinical Endocrinologists (AACE/ACE) diabetes algorithm presented at the American Diabetes Association (ADA) 71st Annual Scientific Sessions, significantly more patients with type 2 diabetes treated with JANUMET (sitagliptin/metformin HCl) tablets achieved blood sugar goals after 18 weeks compared to metformin as initial therapy.

JANUMET is indicated, as an adjunct to diet and exercise, to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both sitagliptin and metformin is appropriate. JANUMET should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis. JANUMET has not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at increased risk of developing pancreatitis while taking JANUMET.

"Close to half of all patients with type 2 diabetes have not achieved adequate blood sugar control, and patients often require combination therapy to reach blood sugar goals," said Barry J. Goldstein, M.D., Ph.D., Vice President and Therapeutic Area Head, Diabetes and Endocrinology, Merck Research Laboratories. "The results of this post-hoc analysis provide additional data regarding the use of combination therapy with JANUMET for appropriate patients."

"The incidence of type 2 diabetes continues to rise in the U.S. and globally, and it is important to help patients achieve blood sugar goals," said Helena Rodbard, M.D., endocrinologist and former AACE president and Co-Chair of the Algorithm Task Force. "It is critical for physicians to work with patients to develop a personalized diabetes treatment plan in accordance with guidelines, such as the AACE/ACE diabetes treatment algorithm."

Sitagliptin, a component of JANUMET, enhances the body's own ability to lower blood sugar levels by increasing
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Contact: Liba Neymotin
liba.neymotin@gcihealth.com
646-321-5736
GCI Health
Source:Eurekalert

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