Navigation Links
In US first, Johns Hopkins surgeons implant brain 'pacemaker' for Alzheimer's disease
Date:12/5/2012

Researchers at Johns Hopkins Medicine in November surgically implanted a pacemaker-like device into the brain of a patient in the early stages of Alzheimer's disease, the first such operation in the United States. The device, which provides deep brain stimulation and has been used in thousands of people with Parkinson's disease, is seen as a possible means of boosting memory and reversing cognitive decline.

The surgery is part of a federally funded, multicenter clinical trial marking a new direction in clinical research designed to slow or halt the ravages of the disease, which slowly robs its mostly elderly victims of a lifetime of memories and the ability to perform the simplest of daily tasks, researchers at Johns Hopkins say. Instead of focusing on drug treatments, many of which have failed in recent clinical trials, the research focuses on the use of the low-voltage electrical charges delivered directly to the brain. There is no cure for Alzheimer's disease.

As part of a preliminary safety study in 2010, the devices were implanted in six Alzheimer's disease patients in Canada. Researchers found that patients with mild forms of the disorder showed sustained increases in glucose metabolism, an indicator of neuronal activity, over a 13-month period. Most Alzheimer's disease patients show decreases in glucose metabolism over the same period.

The first U.S. patient in the new trial underwent surgery at The Johns Hopkins Hospital, and a second patient is scheduled for the same procedure in December. The surgeries at Johns Hopkins are being performed by neurosurgeon William S. Anderson, M.D.

"Recent failures in Alzheimer's disease trials using drugs such as those designed to reduce the buildup of beta amyloid plaques in the brain have sharpened the need for alternative strategies," says Paul B. Rosenberg, M.D., an associate professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine, and
'/>"/>

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. First, do no harm: Study finds danger in standard treatment for a serious lung disease
2. First, Second Kidney Transplants Have Similar Success: Study
3. The US Drug Watchdog Now Urges Any Woman Who Used The Birth Control Pills Yaz Or Yasmin And Then Had A Heart Attack Or Stroke To Call The Johnson Law Group----ASAP
4. The US Drug Watchdog Now Urges Women Who Suffered A Heart Attack Or Stroke After Using Yaz Yasmin Birth Control Pills To Contact The Johnson Law Group Immediately
5. Johns Hopkins scientists pair blood test and gene sequencing to detect cancer
6. Results from study of Mead Johnsons Enfamil® Human Milk Fortifier Acidified Liquid published in Pediatrics
7. Johns Hopkins Armstrong Institute receives $8.9 million patient safety grant
8. Johns Hopkins team finds ICU misdiagnoses may account for as many annual deaths as breast cancer
9. Johns Hopkins researchers return blood cells to stem cell state
10. Johnson & Johnson Violated FDA Order to Halt Sales of Transvaginal Mesh
11. Johns Hopkins African bioethics program receives 5-year continuation grant from NIH
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... 2015 , ... The Heart Fit Clinic has increased a patient's fitness level ... of 150 beats versus 100 beats, this is a big deal," says Diamond Fernandes, ... back to patients with heart disease," he adds. People with angina are able to ...
(Date:7/31/2015)... Birmingham, AL (PRWEB) , ... July 31, 2015 , ... ... Legion Field in Birmingham. The U.S. Women's National Soccer Team will face the ... take place on Thursday, September 17th at Ford Field in Detroit and the second ...
(Date:7/31/2015)... CA (PRWEB) , ... July 31, 2015 , ... ... California, has announced plans to release a newly redesigned website at Healthpointe.net. The ... and enhanced user experience. , The redesign serves to provide smoother interactions ...
(Date:7/31/2015)... ... July 31, 2015 , ... Physical therapy for knee osteoarthritis ... quality of life. It keeps the patient from doing what they want or need to ... a hard time using the stairs. The patient's exercise regime may be limited by the ...
(Date:7/31/2015)... ... July 31, 2015 , ... An article entitled " ... about a woman’s unfortunate experience having cosmetic skin procedures done by a family ... in blistering, swelling, bruising, and pain. This woman’s experience is only one in ...
Breaking Medicine News(10 mins):Health News:Heart Fit Clinic Helps Patient Increase Fitness Level with External Counterpulsation 2Health News:Cheap USA vs. Australia Tickets at Legion Field in Birmingham, AL: Ticket Down Slashes Ticket Prices for Australia vs. USWNT at Legion Field 2Health News:Healthpointe Announces Newly Redesigned Website 2Health News:NYDNRehab Is the First Clinic in NYC to Provide APOS Therapy Based on Results of Complete Gait Analysis 2Health News:NYDNRehab Is the First Clinic in NYC to Provide APOS Therapy Based on Results of Complete Gait Analysis 3Health News:Dermatologists Discuss Rise in Unqualified Practitioners of Cosmetic Dermatology 2Health News:Dermatologists Discuss Rise in Unqualified Practitioners of Cosmetic Dermatology 3
... PORTLAND, Ore., Oct. 20 When Regence member Adrianne Johnson ... friends for recommendations, and then logged on to myRegence.com to ... were patients of those doctors. Based on the Member Reviews ... just a PCP she was comfortable with, but specialists, as ...
... Oct. 20 /PRNewswire-FirstCall/ - MDS Inc. (TSX: MDS; NYSE: ... the global life sciences markets, today announced that Company shareholders ... a leading global supplier of drug discovery and life sciences ... in cash. , A Special Meeting of Shareholders was held ...
... Speaker Nancy Pelosi, House Majority Leader Steny Hoyer, ... held a press availability this afternoon in the Capitol with ... insurance reform for children with pre-existing conditions. Shannon Saunders Eaton ... Texas told their personal stories as ...
... Oct. 20 Justin Timberlake; Sam, Younes and David Nazarian; ... Cedars-Sinai Board of Governors at their annual Gala on ... in Los Angeles, California. The event, sponsored by Lexus, ... As the event sponsor, Lexus donated a 2010 Lexus LS ...
... prostate cancer the most diagnosed cancer for women and ... from these diseases, argue experts from the University of California, ... at San Antonio in an opinion piece published in the ... overall cancer rates are higher, many more patients are being ...
... ... Information and Support , ... Philadelphia, PA (Vocus) October 20, 2009 -- Keystone Mercy Health Plan, the largest ... mammography and pap smear exams, to more than 2,100 women through its Gift for ...
Cached Medicine News:Health News:Regence Takes Community Approach to Provider 'Reviews' 2Health News:Regence Takes Community Approach to Provider 'Reviews' 3Health News:MDS Inc. Announces Shareholder Approval of Sale of MDS Analytical Technologies 2Health News:MDS Inc. Announces Shareholder Approval of Sale of MDS Analytical Technologies 3Health News:Pelosi Remarks at Press Availability with Easter Seals on Benefits of Health Reform for Children 2Health News:Pelosi Remarks at Press Availability with Easter Seals on Benefits of Health Reform for Children 3Health News:Justin Timberlake, Sam Nazarian, Younes Nazarian, David Nazarian, Larry and Sandy Post to Be Honored at 2009 Cedars-Sinai Board of Governors Gala Sponsored By Lexus 2Health News:Experts issue call to reconsider screening for breast cancer and prostate cancer 2Health News:Experts issue call to reconsider screening for breast cancer and prostate cancer 3Health News:Experts issue call to reconsider screening for breast cancer and prostate cancer 4Health News:Experts issue call to reconsider screening for breast cancer and prostate cancer 5Health News:Keystone Mercy Health Plan Initiative Brings Cancer Screenings to Underserved Women in Their Communities 2Health News:Keystone Mercy Health Plan Initiative Brings Cancer Screenings to Underserved Women in Their Communities 3Health News:Keystone Mercy Health Plan Initiative Brings Cancer Screenings to Underserved Women in Their Communities 4
(Date:7/31/2015)... July 31, 2015  Boston Children,s Hospital physicians ... 3D printing of their anatomy before undergoing high-risk ... malformations (abnormalities in the brain,s blood vessels) that ... today in the Journal of Neurosurgery: Pediatrics ... printing and synthetic resins to create custom, high-fidelity ...
(Date:7/31/2015)... , July 31, 2015 According ... by Product (Moist Heat, Dry Heat, Ethylene Oxide, Filtration, E-beam, ... End User (Hospitals, Pharmaceuticals) - Global Forecast to 2020", published ... around USD 6.1 Billion by 2020, at a CAGR of ... 242 market data T ables and ...
(Date:7/31/2015)... 31, 2015  Xcelience, a contract development and ... made a structured cash investment in Powdersize, a ... milling, micronization and powder size classification within the ... business while simultaneously adding a complete set of ... capabilities. "As we continue to ...
Breaking Medicine Technology:3D Printing Helps Doctors Rehearse Complex Brain Procedures 23D Printing Helps Doctors Rehearse Complex Brain Procedures 33D Printing Helps Doctors Rehearse Complex Brain Procedures 4Sterilization Equipment Market is Expected to Reach USD 6.1 Billion by 2020 2Sterilization Equipment Market is Expected to Reach USD 6.1 Billion by 2020 3Sterilization Equipment Market is Expected to Reach USD 6.1 Billion by 2020 4Xcelience Makes Structured Cash Investment in Powdersize 2Xcelience Makes Structured Cash Investment in Powdersize 3
... key role in treatment discovery, MELBOURNE, Australia, ... Cytopia Limited (ASX: CYT) announced today that its ... in cells,isolated from patients with myeloproliferative disorders (MPDs)., ... there is over-production of,particular cells within the blood ...
... Tigris Pharmaceuticals,Inc., a privately held drug development company, ... study of aminoflavone,pro-drug (AFP-464) for the treatment of ... and enrollment is ongoing., The primary objectives ... limiting,toxicity (DLT) and maximum tolerated dose (MTD) of ...
Cached Medicine Technology:JAK2 Inhibitor Shows Potent Activity in Cells From MPD Patients 2Tigris Pharmaceuticals Initiates Phase I Study of AFP-464 in Patients with Solid Tumors 2Tigris Pharmaceuticals Initiates Phase I Study of AFP-464 in Patients with Solid Tumors 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: