Navigation Links
In Time, Cream Might Prevent Herpes Transmission
Date:1/21/2009

Harvard researchers say treatment involving genes works in mice,,

WEDNESDAY, Jan. 21 (HealthDay News) -- A topical treatment that disables genes that play a key role in the transmission of the herpes virus has been developed by U.S. researchers.

The treatment uses RNA interference (RNAi) to fight the virus in two ways: by disabling its ability to replicate and by blocking the host cell's ability to take up the virus. In mice, the treatment is effective when used from one week before to a few hours after exposure to the herpes virus.

"As far as we could tell, the treatment caused no adverse effects, such as inflammation or any kind of autoimmune response," Judy Lieberman, a professor of pediatrics at Harvard Medical School and a senior investigator at the Immune Disease Institute, said in a Harvard news release. In addition, there was no indication that the treatment interfered with normal cellular function.

The research was published in the Jan. 22 issue of the journal Cell Host & Microbe.

"People have been trying to make a topical agent that can prevent transmission, a microbicide, for many years," Lieberman said. "But one of the main obstacles for this is compliance. One of the attractive features of the compound we developed is that it creates in the tissue a state that's resistant to infection, even if applied up to a week before sexual exposure. This aspect has a real practicality to it."

If the findings can be reproduced in people, she said, "this could have a powerful impact on preventing transmission."

According to the World Health Organization, about 536 million people worldwide are infected with herpes simplex virus type 2 (HSV-2), the most common strain of this sexually transmitted disease.

Women are much more likely than men to be infected with HSV-2, and the virus can easily pass from mother to child during birth. Infants with untreated HSV-2 infection can suffer brain damage and death.

In adults, HSV-2 infection isn't life-threatening but does increase vulnerability to other viruses, such as HIV.

More information

The American Social Health Association has more about herpes.



-- Robert Preidt



SOURCE: Harvard Medical School, news release, Jan. 21, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Daytime, Nighttime Blood Pressure Both Important
2. New heart test to save time, money -- and lives
3. Two Little Hands Productions, Creators of Popular Childrens TV Series Signing Time, Debuts Second Season at This Years Toy Fair 2008
4. Choice Hotels Selects PAI as Qualified Vendor to Offer Health Benefits to Part-Time, Hourly Workers in Its Franchisee Base
5. Real Time, Face-to-Face Doctor Visits Now Available Online
6. The DataTrace(R) RF System, the Latest High Performance Radio Data Logger for Real-Time, Process Data Collection, Reporting, and Analysis Is Launched
7. Exclusive Resort Community Looks to MedeFile to Provide Members With Access to Medical Records Anytime, Anywhere
8. BioTime, Inc. and Embryome Sciences, Inc. Launch Embryome.com and the International Embryome Initiative
9. Customers Now Able to Receive Real Time, Online Assistance during Health Insurance Quote Process
10. Scent To Sleep Offers Help for Companies Losing Time, Money to Microsleep
11. Once upon a time, scales were displayed in parlors, not hidden in bathrooms
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
In Time, Cream Might Prevent Herpes Transmission
(Date:6/24/2016)... ... 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out of ... verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all ... brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary ...
(Date:6/24/2016)... ... , ... People across the U.S. are sharpening their pencils and honing their ... in which patients and their families pay tribute to a genetic counselor by nominating ... of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, ...
(Date:6/24/2016)... Las Vegas, Nevada (PRWEB) , ... June 24, ... ... their Las Vegas client, The Grove Investment Group (TGIG), has initiated cultivation and ... The Grove, in Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer ...
(Date:6/24/2016)... ... 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s Wings ... 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... service members that have been wounded in battle and their families. Venture Construction Group ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research ... MEMS Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data ... analysis. Assessment of major trends with potential impact on the ... analysis of market segmentation which comprises of sub markets, regional ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 If ... Leaders Scholarship is any indication, the future is in ... at www.diabetesscholars.org by the Diabetes Scholars Foundation ... the way of academic and community service excellence. ... since 2012, and continues to advocate for people with ...
(Date:6/23/2016)... -- Research and Markets has announced the ... (United States, China, Japan, Brazil, United Kingdom, Germany, France, ... Surgical Procedure Volumes: ... provides surgical procedure volume data in a geographic context. ... analysis of growth drivers and inhibitors, including world population ...
Breaking Medicine Technology: