Navigation Links
In Time, Cream Might Prevent Herpes Transmission
Date:1/21/2009

Harvard researchers say treatment involving genes works in mice,,

WEDNESDAY, Jan. 21 (HealthDay News) -- A topical treatment that disables genes that play a key role in the transmission of the herpes virus has been developed by U.S. researchers.

The treatment uses RNA interference (RNAi) to fight the virus in two ways: by disabling its ability to replicate and by blocking the host cell's ability to take up the virus. In mice, the treatment is effective when used from one week before to a few hours after exposure to the herpes virus.

"As far as we could tell, the treatment caused no adverse effects, such as inflammation or any kind of autoimmune response," Judy Lieberman, a professor of pediatrics at Harvard Medical School and a senior investigator at the Immune Disease Institute, said in a Harvard news release. In addition, there was no indication that the treatment interfered with normal cellular function.

The research was published in the Jan. 22 issue of the journal Cell Host & Microbe.

"People have been trying to make a topical agent that can prevent transmission, a microbicide, for many years," Lieberman said. "But one of the main obstacles for this is compliance. One of the attractive features of the compound we developed is that it creates in the tissue a state that's resistant to infection, even if applied up to a week before sexual exposure. This aspect has a real practicality to it."

If the findings can be reproduced in people, she said, "this could have a powerful impact on preventing transmission."

According to the World Health Organization, about 536 million people worldwide are infected with herpes simplex virus type 2 (HSV-2), the most common strain of this sexually transmitted disease.

Women are much more likely than men to be infected with HSV-2, and the virus can easily pass from mother to child during birth. Infants with untreated HSV-2 infection can suffer brain damage and death.

In adults, HSV-2 infection isn't life-threatening but does increase vulnerability to other viruses, such as HIV.

More information

The American Social Health Association has more about herpes.



-- Robert Preidt



SOURCE: Harvard Medical School, news release, Jan. 21, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Daytime, Nighttime Blood Pressure Both Important
2. New heart test to save time, money -- and lives
3. Two Little Hands Productions, Creators of Popular Childrens TV Series Signing Time, Debuts Second Season at This Years Toy Fair 2008
4. Choice Hotels Selects PAI as Qualified Vendor to Offer Health Benefits to Part-Time, Hourly Workers in Its Franchisee Base
5. Real Time, Face-to-Face Doctor Visits Now Available Online
6. The DataTrace(R) RF System, the Latest High Performance Radio Data Logger for Real-Time, Process Data Collection, Reporting, and Analysis Is Launched
7. Exclusive Resort Community Looks to MedeFile to Provide Members With Access to Medical Records Anytime, Anywhere
8. BioTime, Inc. and Embryome Sciences, Inc. Launch Embryome.com and the International Embryome Initiative
9. Customers Now Able to Receive Real Time, Online Assistance during Health Insurance Quote Process
10. Scent To Sleep Offers Help for Companies Losing Time, Money to Microsleep
11. Once upon a time, scales were displayed in parlors, not hidden in bathrooms
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
In Time, Cream Might Prevent Herpes Transmission
(Date:7/21/2017)... ... July 21, 2017 , ... Fresh Wave® IAQ today announced the launch ... for colleges and universities at the APPA 2017 Annual Conference and Exhibition ... tobacco smoke odors without the use of harsh chemicals, Fresh Wave IAQ Smoke Away ...
(Date:7/21/2017)... (PRWEB) , ... July 21, 2017 , ... The Margarian ... falsely advertising the contents of its ginger ale for allegedly containing no ginger. Dr. ... Dr. Pepper Snapple Group, Inc., plaintiff Gegham Margaryan alleges Canada Dry Ginger Ale claims ...
(Date:7/21/2017)... ... 21, 2017 , ... “Kids aren't born knowing how to regulate their emotions ... Tucker, Founder of St. Louis-based positive education company Generation Mindful. To help with that ... July 21st. , The kit uses colorful, engaging and educational illustrations and games ...
(Date:7/21/2017)... ... July 21, 2017 , ... ... ligament (ACL) offer patients improved quality of life five years after injury, according ... Annual Meeting in Toronto, Ontario, Canada. The study followed patients for five ...
(Date:7/20/2017)... Boston, MA (PRWEB) , ... July 20, 2017 ... ... aggressive form of blood and bone marrow cancer that progresses rapidly without treatment. ... often recommended to reduce the chance of reoccurrence and relapse. With such ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... 13, 2017  Centurion Medical Products, a leader in medical product ... fecal impaction removal device for hospice patient care. ... Centurion Medical Products ... Patient pain management and emotional comfort are part ... alleviate patient pain while preventing unneeded emergency department admission due to ...
(Date:7/11/2017)... IRVINE, Calif. , July 11, 2017 Zymo Research Corp., ... new service that can quantify biological aging in a precise manner using ... Dr. Steve Horvath , a professor of human genetics and biostatistics ... Fielding School of Public Health , Zymo Research,s proprietary DNAge ™ ... loci. ...
(Date:7/11/2017)... July 11, 2017 Oramed Pharmaceuticals Inc. (NASDAQ: ... pharmaceutical company focused on the development of oral drug ... Drug Administration (FDA) has agreed to schedule an End-of-Phase ... IIb trial of its oral insulin capsule ORMD-0801 in ... trial met primary and secondary endpoints by indicating a ...
Breaking Medicine Technology: