Navigation Links
In Landmark Phase III Head-to-Head Study, Prasugrel Statistically Superior to Clopidogrel in Reducing Risk of Heart Attack
Date:11/4/2007

overall events (12.2 vs. 13.9, p=0.004). In the subpopulations defined as being at greater risk of bleeding, the net clinical benefit was not different between prasugrel- and clopidogrel-treated patients (p=0.43). Without the subpopulations defined as being at greater bleeding risk, the net clinical benefit was 20 percent (10.2 vs. 12.5, p<0.001).

Overall, for every 1,000 people treated with prasugrel compared to clopidogrel in the study, there were 23 fewer heart attacks and an additional six major bleeding complications.

"Our study provides compelling evidence that the prasugrel regimen tested is superior to standard dose clopidogrel as an antiplatelet therapy to support patients undergoing coronary stenting," said Elliott Antman, M.D., senior investigator with the TIMI Study Group at Harvard Medical School and director of the Samuel A. Levine Cardiac Unit at Brigham and Women's Hospital in Boston. "With the data from TRITON and other studies, we expect to define populations at particular bleeding risk to help establish clear guidance for using this promising therapy."

Antman announced the initial study results today at the American Heart Association's 2007 Scientific Sessions in Orlando, Florida (abstract 07-LBCT- 20660-AHA). Prasugrel is being co-developed by Daiichi Sankyo Company, Limited (TSE: 4568) and Eli Lilly and Company (NYSE: LLY).

"The TRITON data demonstrate the statistical superiority of this new antiplatelet therapy to prevent heart attacks, and validate our decision to test prasugrel head to head against clopidogrel," said J. Anthony Ware, M.D., Lilly cardiovascular platform leader for prasugrel. "We are very pleased with the trial's outcome and are excited by the potential for these
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. South Africa Wins landmark case against pharmaceutical giants
2. Kolkata: Landmark Health City on the Cards
3. Heart Center at Sinai Conducts Landmark Study on Aspirin Resistance
4. Scientists Map Key Landmarks in Human Genome
5. Landmark Study Prompts Rethink of Genetic Code
6. FDA approves Phase 0 trial which tests experimental drugs on humans
7. SARS-Free Taiwan to Mark End Phase of Global Fight
8. S. Africa AIDS in death phase
9. Spray on contraceptive clears Phase I trial
10. Phase 3 trials of two multi-kinase inhibitors against cancer
11. Antigenics Pharmaceuticals plans for Phase III trial of its Melanoma vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... August 21, 2014 Today, Zane Benefits, ... on the premium tax credits in 2015. , According ... As part of the Affordable Care Act (ACA), premium ... purchase individual health insurance through the Health Insurance Marketplaces. ... eligibility and the amount of the tax credits, updated ...
(Date:8/21/2014)... 21, 2014 An increasing amount of ... that their federal tax payment is being returned by ... come from the IRS, “tax@irs.gov”, it’s actually a phishing ... and financial information. , While similar scams have been ... in phishing activity is occurring right now. , ...
(Date:8/21/2014)... Using heart-lung support technology, the University of Michigan,s ... kidneys, livers and pancreases available for transplant by about ... journal Transplantation and detail the impact of ... or ECMO, to improve the quality and viability of ... transplant is limited by the number of donated organs ...
(Date:8/21/2014)... many people, finding motivation to exercise is a challenge. Thankfully, ... approach of Zombies, Run!one of more than 31,000 health and ... growing number of apps that use games to increase physical ... fitness app makers looking to cash in to help people ... exercise remains to be seen. , "It,s just been assumed ...
(Date:8/21/2014)... Spring, Md. (PRWEB) August 21, 2014 ... to Houston with an Education Forum for PH ... disease. , Who:    The Pulmonary Hypertension Association ... works to find ways to prevent and cure ... lungs that affects the functioning of the heart ...
Breaking Medicine News(10 mins):Health News:Beware Of Phony “Tax Payment Rejected” IRS Emails 2Health News:Extracorporeal support can significantly increase number of organs for transplant 2Health News:Playing hunger games: Are gamified health apps putting odds in your favor? 2Health News:Pulmonary Hypertension Association Goes On the Road to Houston With an Education Forum for PH Patients and Families to Help Fight Rare Lung Disease 2Health News:Pulmonary Hypertension Association Goes On the Road to Houston With an Education Forum for PH Patients and Families to Help Fight Rare Lung Disease 3
... MYL ) announced today that it will host ... 2009, at 10:00 a.m. ET to review the company,s financial ... 2009. Mylan will release its financial results on April ... April 30 call is 877-440-5788 or 719-325-4858 for international callers. ...
... DENVER Genetic variations in the inflammation pathway may ... who might experience a recurrence among patients with non-muscle ... American Association for Cancer Research 100th Annual Meeting 2009. ... like this to create a genetic blueprint for this ...
... symptoms of xerostomia - severe dry mouth - among ... researchers from The University of Texas M. D. Anderson ... Head & Neck . , Xerostomia develops after ... of therapeutic radiation. People who have cancers of the ...
... HUNTINGDON VALLEY, Pa., April 20 They,re young, brave and ... their lives and leave too many with permanent neurological and ... a cure. Teeing up for a cure are former ... who invite golfers to join them, May 4, for the ...
... education program at FDICINDIANAPOLIS, April 20 Continuing in ... nation,s fire service the People,s Burn Foundation is pleased ... Hell and Back burn prevention and safety series. ... participants inside the body through advanced 3-D visualizations to ...
... Fit by Sara and Susan G. Komen for the Cure, San ... April 20 Word is spreading about YOGA 4 THE CURE. ... gathered together to stretch, deep breathe and meditate. Along with ... in donations for breast cancer. Susan G. Komen for the Cure, ...
Cached Medicine News:Health News:Acupuncture eases radiation-induced dry mouth in cancer patients 2Health News:Acupuncture eases radiation-induced dry mouth in cancer patients 3Health News:Vince Papale and Eagles Fly for Leukemia Tee Up for a Cure at May 4, 2009 Celebrity Golf Classic and Auction 2Health News:Discover the Deadly Toxic Twins: Hydrogen Cyanide and Carbon Monoxide 2Health News:Discover the Deadly Toxic Twins: Hydrogen Cyanide and Carbon Monoxide 3Health News:Discover the Deadly Toxic Twins: Hydrogen Cyanide and Carbon Monoxide 4Health News:YOGA 4 THE CURE Raises $1,000 for Breast Cancer 2Health News:YOGA 4 THE CURE Raises $1,000 for Breast Cancer 3
(Date:8/21/2014)... Aug. 21, 2014  Seventy-one percent of Americans believe the ... a serious public health and safety issue in ... survey released today by Repass & Partners, a ... "Americans understand the severity of the prescription medication abuse problem ... this very serious health situation facing our country," Rex ...
(Date:8/21/2014)... 2014  Henry Schein, Inc. (NASDAQ: HSIC ), ... to office-based dental, animal health and medical practitioners, announced today ... September: , September 4, 2014 – Baird 2014 ... 12:50 p.m. ET , September 8, 2014 – ... York , NY at 1:25 p.m. ET ...
(Date:8/21/2014)... , Aug. 21, 2014 CVS Caremark Corporation ... results, applicable Reference Yields and consideration payable in connection with ... on August 7, 2014 for (1) any and all of ... Notes") and (2) up to a maximum amount of its ... and 5.750% Senior Notes due 2017 (collectively, the "Maximum Tender ...
Breaking Medicine Technology:Consumers Desperate For Measures To Curb Prescription Drug Abuse 2Consumers Desperate For Measures To Curb Prescription Drug Abuse 3Henry Schein To Present At Two Investor Conferences In September 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 3CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 4CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 5CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 6
... to complement the active lifestyle, ... contemporary--and comfortable--eyewear for men, women ... offers a wide variety of ... with a young, relaxed attitude, ...
... Whisper NG Erbium YAG Extended Ablation laser ... true laser peel with outstanding results and no ... a proprietary fluence level with an extra long ... skin. Peeling is spread over 3-5 days, ...
... Biomedics EP is the first and only ... are just beginning to have difficulty reading ... ,While everyone wants to enjoy the best ... bifocals or reading glasses. Fortunately, Biomedics EPs ...
... The table-mounted hip ... hands-free exposure for total ... to accommodate individual surgeon ... of any size. Hand-held ...
Medicine Products: