Navigation Links
In Landmark Phase III Head-to-Head Study, Prasugrel Statistically Superior to Clopidogrel in Reducing Risk of Heart Attack
Date:11/4/2007

overall events (12.2 vs. 13.9, p=0.004). In the subpopulations defined as being at greater risk of bleeding, the net clinical benefit was not different between prasugrel- and clopidogrel-treated patients (p=0.43). Without the subpopulations defined as being at greater bleeding risk, the net clinical benefit was 20 percent (10.2 vs. 12.5, p<0.001).

Overall, for every 1,000 people treated with prasugrel compared to clopidogrel in the study, there were 23 fewer heart attacks and an additional six major bleeding complications.

"Our study provides compelling evidence that the prasugrel regimen tested is superior to standard dose clopidogrel as an antiplatelet therapy to support patients undergoing coronary stenting," said Elliott Antman, M.D., senior investigator with the TIMI Study Group at Harvard Medical School and director of the Samuel A. Levine Cardiac Unit at Brigham and Women's Hospital in Boston. "With the data from TRITON and other studies, we expect to define populations at particular bleeding risk to help establish clear guidance for using this promising therapy."

Antman announced the initial study results today at the American Heart Association's 2007 Scientific Sessions in Orlando, Florida (abstract 07-LBCT- 20660-AHA). Prasugrel is being co-developed by Daiichi Sankyo Company, Limited (TSE: 4568) and Eli Lilly and Company (NYSE: LLY).

"The TRITON data demonstrate the statistical superiority of this new antiplatelet therapy to prevent heart attacks, and validate our decision to test prasugrel head to head against clopidogrel," said J. Anthony Ware, M.D., Lilly cardiovascular platform leader for prasugrel. "We are very pleased with the trial's outcome and are excited by the potential for these
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. South Africa Wins landmark case against pharmaceutical giants
2. Kolkata: Landmark Health City on the Cards
3. Heart Center at Sinai Conducts Landmark Study on Aspirin Resistance
4. Scientists Map Key Landmarks in Human Genome
5. Landmark Study Prompts Rethink of Genetic Code
6. FDA approves Phase 0 trial which tests experimental drugs on humans
7. SARS-Free Taiwan to Mark End Phase of Global Fight
8. S. Africa AIDS in death phase
9. Spray on contraceptive clears Phase I trial
10. Phase 3 trials of two multi-kinase inhibitors against cancer
11. Antigenics Pharmaceuticals plans for Phase III trial of its Melanoma vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... Casinos in Australia have grown ... international and online casinos. Revenue is estimated to increase ... through 2014-15. Greater per capita gambling expenditure has assisted ... in discretionary income levels have also assisted revenue growth, ... such as casino gambling services. Revenue is estimated to ...
(Date:7/12/2014)... July 12, 2014 “After my mom’s stroke, she ... a stroke and loss the use of his left side. Eating ... a way to help people like them enjoy eating again,” said ... prototype for the PATRICIA CAROL HALL PLATE (P C H PLATE). ... a more ergonomic way to eat for individuals who suffer from ...
(Date:7/12/2014)... OH (PRWEB) July 12, 2014 Wright & ... against DePuy Orthopedics , Inc., a subsidiary of Johnson & ... he suffers chronic pain after receiving a metal-on-metal DePuy Pinnacle ... later to remove the artificial hip implant. The DePuy hip ... Court, Northern District of Texas (Case No. 3:14-cv-2427) where ...
(Date:7/12/2014)... July 12, 2014 Dubai is buzzing ... legend is heading to the UAE. The National ... will be in the UAE from 28-31 October to ... support of diabetes awareness. The event is being organized ... and event management company based in Dubai. The announcement ...
(Date:7/12/2014)... 12, 2014 Floor-grade instrument ... 4.1 out of 5. This above-average score represents ... underpinning buyer negotiation power over the three years ... Son, “during the period, surging demand for healthcare ... with new product development, have placed upward pressure ...
Breaking Medicine News(10 mins):Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 4Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 2Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 3Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 4Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 5Health News:Los Angeles Basketball Legend Headed to Dubai 2Health News:Los Angeles Basketball Legend Headed to Dubai 3Health News:Floor-Grade Instruments Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Floor-Grade Instruments Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:Floor-Grade Instruments Procurement Category Market Research Report from IBISWorld has Been Updated 4
... successfully respond to drugs that combat the AIDS virus can ... level enjoyed by people without HIV, a study published ... sheds light on poorly understood conditions as to why some ... immune cells, others see a slower increase in these key ...
... unwanted baby girls have been drowned in milk, burned alive in ... these days it is much easier to kill them in the ... in a new book on how a traditional preference for sons ... ,India has only 927 females for every 1,000 males ...
... a gene variant that raises a childs risk of ... attributed to inflammation of the gastrointestinal tract . ... a German study that identified the same gene variant ... is a chronic and painful condition attributed to inflammation ...
... a 58-year-old Texan, went for a swim only to ... surgeries, he is still in danger of losing a ... is fighting necrotizing fasciitis, a tissue-destroying disease caused by ... marketing consultant also is suffering from multiple organ failure ...
... than a thousand prisoners has failed to solve the ... rehabilitation programmes, said the BMA today. ,The ... Ministry of Justices introduction of emergency measures designed to ... A key element of the Government strategy was an ...
... belief that male circumcision can reduce HIV infection rates ... will be told next week . ,David ... conference to be held in Sydney from July 22-25, ... in HIV prevention. ,"We always knew that ...
Cached Medicine News:Health News:HIV Drug Combo can Boost Immune Marker in Long-term Patients: Study 2Health News:New Book Gives Gruesome Account of India Girl Killings 2Health News:New Book Gives Gruesome Account of India Girl Killings 3Health News:Gene Variants for Crohn's Disease Identified 2Health News:Gene Variants for Crohn's Disease Identified 3Health News:Texan Battles Flesh-eating Bacteria Contracted While Swimming 2Health News:Prison Healthcare Continues to Fail Despite Emergency Measures, Warns BMA 2Health News:Male Circumcision can Cut HIV Infection, Studies Show 2
(Date:7/10/2014)...  The U.S. Department of Health and Human Services ... (UH) Case Medical Center Seidman Cancer Center totaling $4.7 ... improving care for patients with complex cancer. ... a unique model developed at UH to enhance care ... or demonstrated need for high health care utilization.  ...
(Date:7/10/2014)... Yesterday, former Congressman Patrick Kennedy ... facility. Rep. Kennedy and Dick Moberg ... research in neurological disease and treatment. ... Garen Staglin , created One Mind, a ... that will radically accelerate the development and implementation ...
(Date:7/10/2014)... 2014  Decision Resources Group finds that while ... specialists are willing to prescribe Durata,s Dalvance (dalbavancin) ... as OPAT, approximately two-thirds of the respondents reported ... hospital inpatients. However, our findings indicate that nearly ... on OPAT following hospital discharge, and most are ...
Breaking Medicine Technology:University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4Representative Patrick Kennedy visits Moberg's medical device facility to discuss improvement in brain injury care 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 3
... (LSE: SHP, NASDAQ: SHPGY ), the global ... agreement with the Center for Drug Evaluation and Research ... to conduct additional clinical trials to confirm the clinical ... 1996 under Subpart H (an accelerated approval process) for ...
...   Remedi SeniorCare , one of the nation,s ... executive Corey Gauff as its new senior vice ... In his new position, Gauff will be responsible ... driving growth via Remedi,s innovative offerings, including the ...
Cached Medicine Technology:ProAmatine® (midodrine HCl) Update: Path Forward Agreed 2ProAmatine® (midodrine HCl) Update: Path Forward Agreed 3ProAmatine® (midodrine HCl) Update: Path Forward Agreed 4Remedi SeniorCare® Appoints Corey Gauff SVP of Sales and Account Management 2
... Nanopipetting System Genesis NPS based on the ... you to miniaturize your assays for high ... and direct dilutions., Furthermore it is ... including gene expression analysis, gene mapping, SNP ...
... is a reagent dispensing system designed to ... microplates. This dispenser can be equipped with ... orifice nozzle heads. Precise plate positioning and ... to a variety of plate types including ...
... Dispenses volumes down to 0.5ul for 384 ... less than 30 seconds per plate significantly ... user interface that provides one-button dispensing. It ... suspensions, beads, or cells, with high precision ...
... QFill2 is the ideal system for fast, accurate ... pressure driven, pinch valve controlled dispensing mechanism, ensures ... all of the components that come into contact ... clean, and autoclave. The unique compact design saves ...
Medicine Products: